Serine protease Omi/HtrA2 targets WARTS kinase to control cell proliferation. (Q53586139)

15 May 2018

title

Serine protease Omi/HtrA2 targets WARTS kinase to control cell proliferation. (English)

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15 May 2018

author name string

Kuninaka S

1

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15 May 2018

Iida SI

2

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15 May 2018

Hara T

3

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15 May 2018

Nomura M

4

1 reference

15 May 2018

Naoe H

5

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15 May 2018

Morisaki T

6

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15 May 2018

Nitta M

7

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15 May 2018

Arima Y

8

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15 May 2018

Mimori T

9

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15 May 2018

Yonehara S

10

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15 May 2018

Saya H

11

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15 May 2018

language of work or name

English

0 references

publication date

20 November 2006

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15 May 2018

published in

Oncogene

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15 May 2018

volume

26

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15 May 2018

issue

17

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15 May 2018

page(s)

2395-2406

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15 May 2018

Men and sin: what's the difference?

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Regulation of HAX-1 anti-apoptotic protein by Omi/HtrA2 protease during cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Zyxin, a regulator of actin filament assembly, targets the mitotic apparatus by interacting with h-warts/LATS1 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Tumor suppressor WARTS ensures genomic integrity by regulating both mitotic progression and G1 tetraploidy checkpoint function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

The tumor suppressor WARTS activates the Omi / HtrA2-dependent pathway of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity

21 January 2018

1 reference

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Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

21 January 2018

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Plat-E: an efficient and stable system for transient packaging of retroviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

A human homolog of Drosophila warts tumor suppressor, h-warts, localized to mitotic apparatus and specifically phosphorylated during mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Spindle checkpoint function is required for mitotic catastrophe induced by DNA-damaging agents

21 January 2018

1 reference

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The HtrA family of serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Omi/HtrA2 promotes cell death by binding and degrading the anti-apoptotic protein ped/pea-15

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

LATS1 tumour suppressor affects cytokinesis by inhibiting LIMK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210042

21 January 2018

Identifiers

DOI

10.1038/SJ.ONC.1210042

1 reference

15 May 2018

1 reference

15 May 2018