BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase. (Q53633362)

16 May 2018

title

BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase. (English)

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16 May 2018

main subject

protein ubiquitination

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7

Sung Hee Baek

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16 May 2018

Chin-Ha Chung

12

object named as

Chin Ha Chung

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16 May 2018

author name string

Jeong Eun Kwon

1

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16 May 2018

Muhnho La

2

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16 May 2018

Kyu Hee Oh

3

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16 May 2018

Young Mi Oh

4

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16 May 2018

Gi Ryang Kim

5

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16 May 2018

Jae Hong Seol

6

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16 May 2018

Tomoki Chiba

8

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16 May 2018

Keiji Tanaka

9

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16 May 2018

Ok Sun Bang

10

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16 May 2018

Cheol O Joe

11

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16 May 2018

language of work or name

English

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publication date

8 March 2006

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16 May 2018

Journal of Biological Chemistry

published in

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16 May 2018

volume

281

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16 May 2018

issue

18

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16 May 2018

page(s)

12664-12672

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16 May 2018

https://api.crossref.org/works/10.1074%2FJBC.M600204200

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Ubiquitin-dependent protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

How proteolysis drives the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

SCF and Cullin/Ring H2-based ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Mechanisms underlying ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Targeting of protein ubiquitination by BTB–Cullin 3–Roc1 ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Daxx, a novel Fas-binding protein that activates JNK and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Daxx Silencing Sensitizes Cells to Multiple Apoptotic Pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Ultraviolet radiation-induced apoptosis is mediated by Daxx

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Regulation of Pax3 transcriptional activity by SUMO-1-modified PML

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

EAP1/Daxx interacts with ETS1 and represses transcriptional activation of ETS1 target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Negative regulation of p53 functions by Daxx and the involvement of MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Daxx-mediated transcriptional repression of MMP1 gene is reversed by SPOP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Identification of a novel nuclear speckle-type protein, SPOP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Covalent modification of all members of human cullin family proteins by NEDD8

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Ets1 is an effector of the transforming growth factor beta (TGF-beta ) signaling pathway and an antagonist of the profibrotic effects of TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Ets factors and regulation of the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

PUMA, a novel proapoptotic gene, is induced by p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

BID regulation by p53 contributes to chemosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

Neddylation and deneddylation of CUL-3 is required to target MEI-1/Katanin for degradation at the meiosis-to-mitosis transition in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M600204200

21 January 2018

Identifiers

DOI

10.1074/JBC.M600204200

1 reference

16 May 2018

PubMed ID

16524876

1 reference

16 May 2018