Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. (Q54217790)

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26 March 2020

title

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses (English)

1 reference

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26 March 2020

16

1 reference

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26 March 2020

Peter T. Hraber

19

1 reference

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26 March 2020

Daniel A. Balikov

23

1 reference

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26 March 2020

Florian Krammer

27

1 reference

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26 March 2020

Norbert Pardi

1

1 reference

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26 March 2020

Michael J Hogan

2

1 reference

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26 March 2020

Kaela Parkhouse

4

1 reference

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26 March 2020

Letitia Jones

6

1 reference

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26 March 2020

M Anthony Moody

7

1 reference

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26 March 2020

Celia C LaBranche

11

1 reference

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26 March 2020

Hua-Xin Liao

15

1 reference

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26 March 2020

Laura L Sutherland

17

1 reference

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26 March 2020

Richard M Scearce

18

1 reference

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26 March 2020

Katalin Karikó

28

1 reference

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26 March 2020

Barton Haynes

38

1 reference

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26 March 2020

Drew Weissman

39

1 reference

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26 March 2020

21

Hiromi Muramatsu

1 reference

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26 March 2020

25

Barbara L Mui

1 reference

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26 March 2020

36

Scott E Hensley

1 reference

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26 March 2020

37

Michael P Cancro

1 reference

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26 March 2020

12

David C Montefiori

1 reference

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26 March 2020

3

Martin S Naradikian

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26 March 2020

5

Derek W Cain

1 reference

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26 March 2020

9

Arpita Myles

1 reference

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26 March 2020

10

Elinor Willis

1 reference

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26 March 2020

14

Kevin O Saunders

1 reference

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26 March 2020

20

István Tombácz

1 reference

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26 March 2020

29

Patricia Polacino

1 reference

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26 March 2020

31

Thomas D Madden

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26 March 2020

35

Shiu-Lok Hu

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26 March 2020

author name string

Hans P Verkerke

8

1 reference

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26 March 2020

Jenna L Lobby

13

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26 March 2020

Houping Ni

22

1 reference

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26 March 2020

Charles Li

24

1 reference

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26 March 2020

Ying K Tam

26

1 reference

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26 March 2020

Laurence C Eisenlohr

30

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26 March 2020

Michael J Hope

32

1 reference

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26 March 2020

Kelly K Lee

34

1 reference

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26 March 2020

Mark G Lewis

33

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26 March 2020

language of work or name

English

0 references

publication date

8 May 2018

1 reference

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Journal of Experimental Medicine

26 March 2020

published in

1 reference

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26 March 2020

volume

215

1 reference

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26 March 2020

page(s)

1571-1588

1 reference

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26 March 2020

issue

6

1 reference

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mRNA vaccines - a new era in vaccinology.

26 March 2020

cites work

1 reference

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Unmodified mRNA in LNPs constitutes a competitive technology for prophylactic vaccines.

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Induction of Robust B Cell Responses after Influenza mRNA Vaccination Is Accompanied by Circulating Hemagglutinin-Specific ICOS+ PD-1+ CXCR3+ T Follicular Helper Cells.

29 September 2018

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Efficient Targeting and Activation of Antigen-Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques

29 September 2018

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Safety and immunogenicity of a mRNA rabies vaccine in healthy adults: an open-label, non-randomised, prospective, first-in-human phase 1 clinical trial

29 September 2018

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Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

29 September 2018

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Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses

29 September 2018

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Modified mRNA Vaccines Protect against Zika Virus Infection

29 September 2018

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Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination

29 September 2018

1 reference

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Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem

29 September 2018

1 reference

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Water-in-Oil-Only Adjuvants Selectively Promote T Follicular Helper Cell Polarization through a Type I IFN and IL-6-Dependent Pathway.

29 September 2018

1 reference

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Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination

29 September 2018

1 reference

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Activin A programs the differentiation of human TFH cells

29 September 2018

1 reference

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An mRNA Vaccine Encoding Rabies Virus Glycoprotein Induces Protection against Lethal Infection in Mice and Correlates of Protection in Adult and Newborn Pigs

29 September 2018

1 reference

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Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique

29 September 2018

1 reference

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Progress in developing virus-like particle influenza vaccines.

29 September 2018

1 reference

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Designing therapeutic cancer vaccines by mimicking viral infections

29 September 2018

1 reference

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Novel universal influenza virus vaccine approaches

29 September 2018

1 reference

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Materials for non-viral intracellular delivery of messenger RNA therapeutics

29 September 2018

1 reference

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Functional Specialization of Skin Dendritic Cell Subsets in Regulating T Cell Responses

29 September 2018

1 reference

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Germinal center selection and the antibody response to influenza

29 September 2018

1 reference

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N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice

29 September 2018

1 reference

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Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (TFH) in Simian Immunodeficiency Virus-Infected Rhesus Macaques May Contribute to Accumulation of TFH in Chronic Infection

29 September 2018

1 reference

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Expression kinetics of nucleoside-modified mRNA delivered in lipid nanoparticles to mice by various routes

29 September 2018

1 reference

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Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection

29 September 2018

1 reference

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Targeting Antigen to Clec9A Primes Follicular Th Cell Memory Responses Capable of Robust Recall

29 September 2018

1 reference

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Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals

29 September 2018

1 reference

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Skin dendritic cells induce follicular helper T cells and protective humoral immune responses

29 September 2018

1 reference

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MF59 Mediates Its B Cell Adjuvanticity by Promoting T Follicular Helper Cells and Thus Germinal Center Responses in Adult and Early Life.

29 September 2018

1 reference

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T follicular helper cell differentiation, function, and roles in disease

29 September 2018

1 reference

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Lymphatic-targeted cationic liposomes: a robust vaccine adjuvant for promoting long-term immunological memory.

29 September 2018

1 reference

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Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains

29 September 2018

1 reference

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Toll-like receptor agonist augments virus-like particle-mediated protection from Ebola virus with transient immune activation

29 September 2018

1 reference

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Broadly neutralizing antibodies and the search for an HIV-1 vaccine: the end of the beginning

29 September 2018

1 reference

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The use of self-adjuvanting nanofiber vaccines to elicit high-affinity B cell responses to peptide antigens without inflammation

29 September 2018

1 reference

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A novel, disruptive vaccination technology: self-adjuvanted RNActive(®) vaccines

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987916

Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987916

Purification of recombinant vaccinia virus-expressed monomeric HIV-1 gp120 to apparent homogeneity

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987916

Synthetic DNA vaccine strategies against persistent viral infections

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987916

HPLC purification of in vitro transcribed long RNA.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987916

In vitro transcription of long RNA containing modified nucleosides

29 September 2018

1 reference

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Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies

29 September 2018

1 reference

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Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987916

Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5987916

29 September 2018

1 reference

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Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA.

29 September 2018

1 reference

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Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype.

29 September 2018

1 reference

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Cross-reactive monoclonal antibodies to multiple HIV-1 subtype and SIVcpz envelope glycoproteins

29 September 2018

1 reference

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Type I interferon signaling in dendritic cells stimulates the development of lymph-node-resident T follicular helper cells

29 September 2018

1 reference

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Measuring HIV neutralization in a luciferase reporter gene assay

29 September 2018

1 reference

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Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability

29 September 2018

1 reference

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Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs

29 September 2018

1 reference

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Characterization of a thymus-tropic HIV-1 isolate from a rapid progressor: role of the envelope

29 September 2018

1 reference

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Immunogenicity and protective efficacy of influenza vaccination

29 September 2018

1 reference

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Induction of virus-specific cytotoxic T lymphocytes in vivo by liposome-entrapped mRNA.

29 September 2018

1 reference

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29 September 2018

Identifiers

DOI

10.1084/JEM.20171450

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29739835%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29739835%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference