Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol. (Q54462984)

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25 December 2019

title

Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol (English)

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25 December 2019

4

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25 December 2019

Kei-ichi Takata

series ordinal

1

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25 December 2019

author name string

Tatsuhiko Shimizu

series ordinal

2

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25 December 2019

Shigenori Iwai

series ordinal

3

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25 December 2019

language of work or name

English

0 references

publication date

19 June 2006

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Journal of Biological Chemistry

25 December 2019

published in

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25 December 2019

volume

281

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25 December 2019

issue

33

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25 December 2019

page(s)

23445-23455

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Eukaryotic DNA Polymerases

25 December 2019

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POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308

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The Drosophila mus 308 gene product, implicated in tolerance of DNA interstrand crosslinks, is a nuclear protein found in both ovaries and embryos.

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High-efficiency bypass of DNA damage by human DNA polymerase Q

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A conserved Tyr residue is required for sugar selectivity in a Pol alpha DNA polymerase

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Synthesis and characterization of a substrate for T4 endonuclease V containing a phosphorodithioate linkage at the thymine dimer site

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Preferential formation of (5S,6R)-thymine glycol for oligodeoxyribonucleotide synthesis and analysis of drug binding to thymine glycol-containing DNA.

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An intrastrand d(GpG) platinum crosslink in duplex M13 DNA is refractory to repair by human cell extracts

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Translesion synthesis by human DNA polymerase eta across thymine glycol lesions

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Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

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Novel non-templated nucleotide addition reactions catalyzed by procaryotic and eucaryotic DNA polymerases

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A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M604317200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16787914%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference