Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor. (Q54611050)

1 June 2018

title

Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor. (English)

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author name string

Yu-Feng Dong

1

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Do Y Soung

2

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Edward M Schwarz

3

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Regis J O'Keefe

4

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Hicham Drissi

5

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publication date

1 July 2006

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Journal of Cellular Physiology

published in

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volume

208

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issue

1

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page(s)

77-86

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beta-catenin is a target for the ubiquitin-proteasome pathway

cites work

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Interactions between Sox9 and beta-catenin control chondrocyte differentiation

21 January 2018

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Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development

21 January 2018

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Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis

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Wnt-5a and Wnt-7a are expressed in the developing chick limb bud in a manner suggesting roles in pattern formation along the proximodistal and dorsoventral axes.

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1,25-(OH)2-vitamin D3 suppresses the bone-related Runx2/Cbfa1 gene promoter

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Identification of novel protein/DNA interactions within the promoter of the bone-related transcription factor Runx2/Cbfa1.

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Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes

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Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

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The Wnt antagonist Frzb-1 regulates chondrocyte maturation and long bone development during limb skeletogenesis

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Regulation of the osteoblast-specific transcription factor, Runx2: responsiveness to multiple signal transduction pathways

21 January 2018

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Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation

21 January 2018

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Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation

21 January 2018

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Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton

21 January 2018

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Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

21 January 2018

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The Frizzled family: receptors for multiple signal transduction pathways

21 January 2018

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Maturational disturbance of chondrocytes in Cbfa1-deficient mice

21 January 2018

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RUNX transcription factors as key targets of TGF-beta superfamily signaling

21 January 2018

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Runx2 expression and action in chondrocytes are regulated by retinoid signaling and parathyroid hormone-related peptide (PTHrP).

21 January 2018

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WNT signals control FGF-dependent limb initiation and AER induction in the chick embryo.

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Secreted antagonists of the Wnt signalling pathway

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Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud.

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Regulation of chondrocyte differentiation by Cbfa1

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Runx2, a multifunctional transcription factor in skeletal development

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Regulation of skeletal development by the Runx family of transcription factors

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

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The WNT/calcium pathway: biochemical mediators, tools and future requirements

21 January 2018

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Nkx3.2-mediated repression of Runx2 promotes chondrogenic differentiation

21 January 2018

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Retinoic acid stimulates chondrocyte differentiation and enhances bone morphogenetic protein effects through induction of Smad1 and Smad5.

21 January 2018

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Parathyroid hormone-related peptide (PTHrP) inhibits Runx2 expression through the PKA signaling pathway.

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Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors

21 January 2018

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Mechanism and function of signal transduction by the Wnt/beta-catenin and Wnt/Ca2+ pathways

21 January 2018

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WNT and beta-catenin signalling: diseases and therapies

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Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

21 January 2018

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Inhibition of chondrogenesis by Wnt gene expression in vivo and in vitro.

21 January 2018

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Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development

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Role of Runx genes in chondrocyte differentiation

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Developmental regulation of Wnt/beta-catenin signals is required for growth plate assembly, cartilage integrity, and endochondral ossification.

21 January 2018

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Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes

21 January 2018

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A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling

21 January 2018

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Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation

21 January 2018

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Wnt5a and Wnt5b exhibit distinct activities in coordinating chondrocyte proliferation and differentiation.

21 January 2018

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The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner.

21 January 2018

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Identifiers

DOI

10.1002/JCP.20656

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