Mitogen-activated protein kinase-activated protein kinase 2 (MK2) contributes to secondary damage after spinal cord injury. (Q54643471)

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15 February 2020

title

Mitogen-activated protein kinase-activated protein kinase 2 (MK2) contributes to secondary damage after spinal cord injury (English)

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1

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Ruben Lopez-vales

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Matthias Gaestel

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Danuta Radzioch

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author name string

Claude Lachance

3

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Thusanth Thuraisingam

4

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Samuel David

7

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language of work or name

English

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publication date

1 October 2010

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15 February 2020

published in

Journal of Neuroscience

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volume

30

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issue

41

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15 February 2020

page(s)

13750-13759

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15 February 2020

ImageQuant

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inferred from PubMed Central ID database lookup

cites work

Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury

1 reference

12 December 2020

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism.

1 reference

12 December 2020

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

1 reference

12 December 2020

KEGG: kyoto encyclopedia of genes and genomes

1 reference

12 December 2020

Activation of locomotion in adult chronic spinal rats is achieved by transplantation of embryonic raphe cells reinnervating a precise lumbar level

1 reference

12 December 2020

The role of reactive nitrogen species in secondary spinal cord injury: formation of nitric oxide, peroxynitrite, and nitrated protein

1 reference

12 December 2020

SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung

1 reference

12 December 2020

Hsp27-induced MMP-9 expression is influenced by the Src tyrosine protein kinase yes.

1 reference

12 December 2020

Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability

1 reference

12 December 2020

A neutrophil elastase inhibitor (ONO-5046) reduces neurologic damage after spinal cord injury in rats

1 reference

12 December 2020

MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels

1 reference

12 December 2020

Mitogen-activated protein kinase-activated protein kinase 2-deficient mice show increased susceptibility to Listeria monocytogenes infection

1 reference

12 December 2020

Distinct cellular functions of MK2.

1 reference

12 December 2020

The neuropathological and behavioral consequences of intraspinal microglial/macrophage activation.

1 reference

12 December 2020

Locomotor recovery in the chronic spinal rat: effects of long-term treatment with a 5-HT2 agonist.

1 reference

12 December 2020

Matrix metalloproteinases limit functional recovery after spinal cord injury by modulation of early vascular events.

1 reference

12 December 2020

Mitogen-activated protein kinase-activated protein (MAPKAP) kinase 2 deficiency protects brain from ischemic injury in mice.

1 reference

12 December 2020

Summaries of Affymetrix GeneChip probe level data

1 reference

12 December 2020

Increased production of tumor necrosis factor-alpha induces apoptosis after traumatic spinal cord injury in rats

1 reference

12 December 2020

Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system

1 reference

12 December 2020

p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.

1 reference

12 December 2020

Rats and mice exhibit distinct inflammatory reactions after spinal cord injury

1 reference

12 December 2020

Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice

1 reference

12 December 2020

Differential temporal expression of matrix metalloproteinases after spinal cord injury: relationship to revascularization and wound healing

1 reference

12 December 2020

Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins

1 reference

12 December 2020

Continuous intrathecal infusion of SB203580, a selective inhibitor of p38 mitogen-activated protein kinase, reduces the damage of hind-limb function after thoracic spinal cord injury in rat

1 reference

12 December 2020

An Adverse Role for Matrix Metalloproteinase 12 after Spinal Cord Injury in Mice

1 reference

12 December 2020

MAPKAP kinase 2 phosphorylates tristetraprolin on in vivo sites including Ser178, a site required for 14-3-3 binding

1 reference

12 December 2020

GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies

1 reference

12 December 2020

Minocycline treatment reduces delayed oligodendrocyte death, attenuates axonal dieback, and improves functional outcome after spinal cord injury.

1 reference

12 December 2020

Early anti-inflammatory treatment reduces lipid peroxidation and protein nitration after spinal cord injury in rats.

1 reference

12 December 2020

Transient blockade of the CD11d/CD18 integrin reduces secondary damage after spinal cord injury, improving sensory, autonomic, and motor function.

1 reference

12 December 2020

Early expression and cellular localization of proinflammatory cytokines interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in human traumatic spinal cord injury.

1 reference

12 December 2020

ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

1 reference

12 December 2020

The p38 MAP kinase pathway as a therapeutic target in inflammatory disease

1 reference

12 December 2020

Anti-CD11d integrin antibody treatment restores normal serotonergic projections to the dorsal, intermediate, and ventral horns of the injured spinal cord.

1 reference

12 December 2020

MIP-1alpha[CCL3] acting on the CCR1 receptor mediates neutrophil migration in immune inflammation via sequential release of TNF-alpha and LTB4

1 reference

12 December 2020

BABELOMICS: a suite of web tools for functional annotation and analysis of groups of genes in high-throughput experiments.

1 reference

12 December 2020

Tissue displacement and impact force are important contributors to outcome after spinal cord contusion injury.

1 reference

12 December 2020

Strategies to promote neural repair and regeneration after spinal cord injury

1 reference

12 December 2020

Matrix metalloproteinase-2 and -9 are induced differently by doxorubicin in H9c2 cells: The role of MAP kinases and NAD(P)H oxidase.

1 reference

12 December 2020

Comparative analysis of lesion development and intraspinal inflammation in four strains of mice following spinal contusion injury

1 reference

12 December 2020

MAPKAPK2 and HSP27 are downstream effectors of p38 MAP kinase-mediated matrix metalloproteinase type 2 activation and cell invasion in human prostate cancer

1 reference

12 December 2020

MAPKAP kinases - MKs - two's company, three's a crowd

1 reference

12 December 2020

New approaches to the treatment of inflammatory disorders small molecule inhibitors of p38 MAP kinase.

1 reference

12 December 2020

Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element

1 reference

12 December 2020

CXCL12 and C5a trigger cell migration via a PAK1/2-p38α MAPK-MAPKAP-K2-HSP27 pathway

1 reference

12 December 2020

Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains.

1 reference

12 December 2020

MAPK-activated protein kinase 2 deficiency in microglia inhibits pro-inflammatory mediator release and resultant neurotoxicity. Relevance to neuroinflammation in a transgenic mouse model of Alzheimer disease

1 reference

12 December 2020

IL-12, but not IL-18, is critical to neutrophil activation and resistance to polymicrobial sepsis induced by cecal ligation and puncture

1 reference

12 December 2020

Functions of the MAPK family in vertebrate-development

1 reference

12 December 2020

ERK1/2 and p38 mitogen-activated protein kinase mediate iNOS-induced spinal neuron degeneration after acute traumatic spinal cord injury

1 reference

12 December 2020

Matrix metalloproteinase-2 facilitates wound healing events that promote functional recovery after spinal cord injury

1 reference

12 December 2020

Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved.

1 reference

12 December 2020

Role of peroxynitrite in secondary oxidative damage after spinal cord injury.

1 reference

12 December 2020

Heat shock protein 27 functions in inflammatory gene expression and transforming growth factor-beta-activated kinase-1 (TAK1)-mediated signaling.

1 reference

12 December 2020

Characterization of the early neuroinflammation after spinal cord injury in mice.

1 reference

12 December 2020

Distinct role of MAPKAPK-2 in the regulation of TNF gene expression by Toll-like receptor 7 and 9 ligands

1 reference

12 December 2020

Inhibiting epidermal growth factor receptor improves structural, locomotor, sensory, and bladder recovery from experimental spinal cord injury.

1 reference

12 December 2020

Minocycline alleviates death of oligodendrocytes by inhibiting pro-nerve growth factor production in microglia after spinal cord injury.

1 reference

12 December 2020

Inflammation and its role in neuroprotection, axonal regeneration and functional recovery after spinal cord injury

1 reference

12 December 2020

Systemic Deficiency of the MAP Kinase–Activated Protein Kinase 2 Reduces Atherosclerosis in Hypercholesterolemic Mice

1 reference

12 December 2020

Targeting MMPs in acute and chronic neurological conditions

1 reference

12 December 2020

MAPKAP kinase 2-deficiency prevents neurons from cell death by reducing neuroinflammation – relevance in a mouse model of Parkinson’s disease

1 reference

12 December 2020

P2Y12 receptor upregulation in activated microglia is a gateway of p38 signaling and neuropathic pain

1 reference

12 December 2020

A molecular platform in neurons regulates inflammation after spinal cord injury

1 reference

12 December 2020

Dynamics of the inflammatory response after murine spinal cord injury revealed by flow cytometry

1 reference

12 December 2020

Can the immune system be harnessed to repair the CNS?

1 reference

12 December 2020

SB203580, a p38 mitogen-activated protein kinase inhibitor, fails to improve functional outcome following a moderate spinal cord injury in rat

1 reference

12 December 2020

Activation of p38 MAP kinase is involved in central neuropathic pain following spinal cord injury

1 reference

12 December 2020

Ceruloplasmin protects injured spinal cord from iron-mediated oxidative damage.

1 reference

12 December 2020

Matrix metalloproteinase-9 facilitates glial scar formation in the injured spinal cord

1 reference

12 December 2020

Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome.

1 reference

12 December 2020

Inhibition of HSP27 phosphorylation by a cell-permeant MAPKAP Kinase 2 inhibitor

1 reference

12 December 2020

Phosphorylation dependence of hsp27 multimeric size and molecular chaperone function

1 reference

12 December 2020

Targeting innate immunity protein kinase signalling in inflammation

1 reference

12 December 2020

Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord

1 reference

12 December 2020

Inhibition of mononuclear phagocytes reduces ischemic injury in the spinal cord

1 reference

12 December 2020

TNF-alpha mediates recruitment of neutrophils and eosinophils during airway inflammation

1 reference

12 December 2020

Tumor necrosis factor-alpha expression in ischemic neurons.

1 reference

12 December 2020

Effects of silica on the outcome from experimental spinal cord injury: implication of macrophages in secondary tissue damage

1 reference

12 December 2020

Effects of exogenous transforming growth factor-beta 1 on spinal cord injury in rats

1 reference

12 December 2020

Role of neutrophils in spinal cord injury in the rat

1 reference

12 December 2020

Expression of pro-inflammatory cytokine and chemokine mRNA upon experimental spinal cord injury in mouse: an in situ hybridization study.

1 reference

12 December 2020

Selective chemokine mRNA accumulation in the rat spinal cord after contusion injury.

1 reference

12 December 2020

Possible involvement of interleukin-1 in cyclooxygenase-2 induction after spinal cord injury in rats

1 reference

12 December 2020

10.1523/JNEUROSCI.2998-10.2010

Identifiers

DOI

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