NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B4 in a murine model of gout (Q56797722)

Raphael S. Peres

12

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Dario S. Zamboni

Dario S. Zamboni

10

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Fernando Queiroz Cunha

Fernando Q. Cunha

14

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Bernhard Ryffel

15

Bernhard Ryffel

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Thiago Mattar Cunha

13

Thiago M. Cunha

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Mauro M Teixeira

17

Mauro M. Teixeira

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Frederico M Soriani

7

Frederico M. Soriani

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Larissa Cunha

9

Larissa D. Cunha

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Daniela Sachs

4

Daniela Sachs

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Flavio A Amaral

1

Flávio A. Amaral

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author name string

Livia D. Tavares

3

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Fernanda M. Coelho

5

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Caio T. Fagundes

6

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Tatiana N. Silveira

8

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Valerie Quesniaux

11

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Daniele G. Souza

Altered uric acid levels and disease states

16

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publication date

27 January 2012

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published in

Arthritis and Rheumatism

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volume

64

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page(s)

474-484

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issue

2

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cites work

1 reference

Developments in the scientific and clinical understanding of gout

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Mechanisms of uric acid crystal-mediated autoinflammation

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Immunochemical and ultrastructural characterization of serum proteins associated with monosodium urate crystals (MSU) in synovial fluid cells from patients with gout

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A role of IgM antibodies in monosodium urate crystal formation and associated adjuvanticity

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Receptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells

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NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

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Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.

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Gout-associated uric acid crystals activate the NALP3 inflammasome

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Crystals of monosodium urate monohydrate enhance lipopolysaccharide-induced release of interleukin 1 beta by mononuclear cells through a caspase 1-mediated process

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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

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Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

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Production of mice deficient in genes for interleukin (IL)-1alpha, IL-1beta, IL-1alpha/beta, and IL-1 receptor antagonist shows that IL-1beta is crucial in turpentine-induced fever development and glucocorticoid secretion

21 January 2018

1 reference

MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals

21 January 2018

1 reference

Cooperative role of tumour necrosis factor-α, interleukin-1β and neutrophils in a novel behavioural model that concomitantly demonstrates articular inflammation and hypernociception in mice

21 January 2018

1 reference

The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature

21 January 2018

1 reference

The critical role of leukotriene B4 in antigen-induced mechanical hyperalgesia in immunised rats

21 January 2018

1 reference

Resident macrophages initiating and driving inflammation in a monosodium urate monohydrate crystal-induced murine peritoneal model of acute gout

21 January 2018

1 reference

Crystal-induced neutrophil activation

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1 reference

The murine homolog of the interleukin-8 receptor CXCR-2 is essential for the occurrence of neutrophilic inflammation in the air pouch model of acute urate crystal-induced gouty synovitis.

21 January 2018

1 reference

In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand flies.

21 January 2018

1 reference

Crucial role of neutrophils in the development of mechanical inflammatory hypernociception

21 January 2018

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1 reference

Adverse effects of the classic antioxidant uric acid in adipocytes: NADPH oxidase-mediated oxidative/nitrosative stress

21 January 2018

1 reference

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

21 January 2018

1 reference

Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis

21 January 2018

1 reference

Caspase 1-independent activation of interleukin-1beta in neutrophil-predominant inflammation

21 January 2018

1 reference

Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis

21 January 2018

1 reference

Silica Crystals and Aluminum Salts Regulate the Production of Prostaglandin in Macrophages via NALP3 Inflammasome-Independent Mechanisms

21 January 2018

1 reference

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

21 January 2018

1 reference

Lysosomal release of cathepsins causes ischemic damage in the rat hippocampal slice and depends on NMDA-mediated calcium influx, arachidonic acid metabolism, and free radical production.

21 January 2018

1 reference

Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration

21 January 2018

1 reference

ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages

21 January 2018

1 reference

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

21 January 2018

1 reference

Neutrophil oxygen radical generation. Synergistic responses to tumor necrosis factor and mono/polyunsaturated fatty acids

21 January 2018

1 reference