CD200-CD200R signaling suppresses anti-tumor responses independently of CD200 expression on the tumor (Q57204153)

1

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G Karnam

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G Goverse

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A P J van der Marel

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M J Greuter

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R A van Schaarenburg

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W F Visser

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A B Brenkman

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R Molenaar

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R M Hoek

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R E Mebius

IDO activates regulatory T cells and blocks their conversion into Th17-like T cells

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language of work or name

English

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publication date

24 October 2011

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published in

Oncogene

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volume

31

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issue

24

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page(s)

2979-2988

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cites work

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Critical regulation of early Th17 cell differentiation by interleukin-1 signaling

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Murine plasmacytoid dendritic cells initiate the immunosuppressive pathway of tryptophan catabolism in response to CD200 receptor engagement

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Quantitation of early clonal expansion of two mutant 61st codon c-Ha-ras alleles in DMBA/TPA treated mouse skin by nested PCR/RFLP.

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Th17 cytokines and their emerging roles in inflammation and autoimmunity

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Down-regulation of the macrophage lineage through interaction with OX2 (CD200)

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Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

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CD200 expression on tumor cells suppresses antitumor immunity: new approaches to cancer immunotherapy

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Endogenous IL-17 contributes to reduced tumor growth and metastasis

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Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.

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Up for Mischief? IL-17/Th17 in the tumour microenvironment

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T helper 17 cells promote cytotoxic T cell activation in tumor immunity

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Antibodies selected from combinatorial libraries block a tumor antigen that plays a key role in immunomodulation

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Inhibitory feedback loop between tolerogenic dendritic cells and regulatory T cells in transplant tolerance

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Lymph node stromal cells support dendritic cell-induced gut-homing of T cells.

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CD200 is a new prognostic factor in multiple myeloma

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Effector T cell plasticity: flexibility in the face of changing circumstances

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Disruption of T cell suppression in chronic lymphocytic leukemia by CD200 blockade.

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Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis

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Modulation of lymphocyte regulation for cancer therapy: a phase II trial of tremelimumab in advanced gastric and esophageal adenocarcinoma.

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The inhibitory CD200R is differentially expressed on human and mouse T and B lymphocytes.

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Expression of CD200 on epithelial cells of the murine hair follicle: a role in tissue-specific immune tolerance?

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Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice

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Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes.

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Immune modulation by melanoma and ovarian tumor cells through expression of the immunosuppressive molecule CD200.

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Enhanced tolerance to autoimmune uveitis in CD200-deficient mice correlates with a pronounced Th2 switch in response to antigen challenge

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CD200 as a prognostic factor in acute myeloid leukaemia.

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IL-17 enhances tumor development in carcinogen-induced skin cancer

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Th17 cells in cancer: help or hindrance?

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The role of CD200 in immunity to B cell lymphoma

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The unusual distribution of the neuronal/lymphoid cell surface CD200 (OX2) glycoprotein is conserved in humans

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TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

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Immune inhibitory ligand CD200 induction by TLRs and NLRs limits macrophage activation to protect the host from meningococcal septicemia

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A critical function for CD200 in lung immune homeostasis and the severity of influenza infection

31 March 2020

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Early Events in Peripheral Regulatory T Cell Induction via the Nasal Mucosa

31 March 2020

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Nasal tolerance induces antigen-specific CD4+CD25- regulatory T cells that can transfer their regulatory capacity to naive CD4+ T cells

31 March 2020

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Blockade of IDO inhibits nasal tolerance induction

31 March 2020

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Mucosal tolerance is associated with, but independent of, up-regulation Th2 responses

31 March 2020

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Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta

31 March 2020

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