Chapter 11 Caveolin Proteins in Cardiopulmonary Disease and Lung Cancers (Q57364644)

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7 January 2021

Up-regulation of caveolin expression by cytotoxic agents in drug-sensitive cancer cells

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7 January 2021

The basic helix-loop-helix transcription factors myogenin and Id2 mediate specific induction of caveolin-3 gene expression during embryonic development

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7 January 2021

Alterations in nitric oxide production in 8-week-old lambs with increased pulmonary blood flow

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7 January 2021

The cardiac sodium-calcium exchanger associates with caveolin-3.

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7 January 2021

In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation

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7 January 2021

Caveolin-1 expression and caveolae biogenesis during cell transdifferentiation in lung alveolar epithelial primary cultures

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7 January 2021

Senescent phenotype can be reversed by reduction of caveolin status

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7 January 2021

Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts

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7 January 2021

Up-regulation of cardiac nitric oxide synthase 1-derived nitric oxide after myocardial infarction in senescent rats.

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7 January 2021

Increased neuronal nitric oxide synthase-derived NO production in the failing human heart

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7 January 2021

Type B atrial natriuretic peptide receptor in cardiac myocyte caveolae

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7 January 2021

Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice

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7 January 2021

Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers

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7 January 2021

Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines

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7 January 2021

Endothelial nitric oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells

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7 January 2021

Modulation of the endothelial nitric-oxide synthase-caveolin interaction in cardiac myocytes. Implications for the autonomic regulation of heart rate.

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7 January 2021

Dynamic targeting of the agonist-stimulated m2 muscarinic acetylcholine receptor to caveolae in cardiac myocytes

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7 January 2021

Impaired NO signaling in small pulmonary arteries of chronically hypoxic newborn piglets

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7 January 2021

Accumulation of molecules involved in alpha1-adrenergic signal within caveolae: caveolin expression and the development of cardiac hypertrophy

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7 January 2021

Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

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7 January 2021

Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism.

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7 January 2021

Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1

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7 January 2021

Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling

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7 January 2021

Specific binding sites for albumin restricted to plasmalemmal vesicles of continuous capillary endothelium: receptor-mediated transcytosis

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7 January 2021

Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1.

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7 January 2021

Selective inhibition of tumor microvascular permeability by cavtratin blocks tumor progression in mice

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7 January 2021

Overexpression of the sarcolemmal calcium pump in the myocardium of transgenic rats

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7 January 2021

Contribution of caveolin protein abundance to augmented nitric oxide signaling in conscious dogs with pacing-induced heart failure

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7 January 2021

Identification and functional analysis of a caveolin-3 mutation associated with familial hypertrophic cardiomyopathy

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7 January 2021

Up-regulated caveolin-1 accentuates the metastasis capability of lung adenocarcinoma by inducing filopodia formation

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7 January 2021

The cyclin D1 gene is transcriptionally repressed by caveolin-1.

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7 January 2021

Lung remodeling and pulmonary hypertension after myocardial infarction: pathogenic role of reduced caveolin expression.

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7 January 2021

Increased expression of caveolin-1 and microvessel density correlates with metastasis and poor prognosis in clear cell renal cell carcinoma

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7 January 2021

Loss of caveolin expression in type I pneumocytes as an indicator of subcellular alterations during lung fibrogenesis

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7 January 2021

Early signs of lung fibrosis after in vitro treatment of rat lung slices with CdCl2 and TGF-beta1

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7 January 2021

Transcription of the caveolin-1 gene is differentially regulated in lung type I epithelial and endothelial cell lines. A role for ETS proteins in epithelial cell expression

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7 January 2021

Overexpression of caveolin-1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage

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7 January 2021

Changes in caveolin subtype protein expression in aging rat organs.

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7 January 2021

TCV-116 stimulates eNOS and caveolin-1 expression and improves coronary microvascular remodeling in normotensive and angiotensin II-induced hypertensive rats

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7 January 2021

Adenovirus-mediated overexpression of caveolin-3 inhibits rat cardiomyocyte hypertrophy

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7 January 2021

Cell type-specific occurrence of caveolin-1alpha and -1beta in the lung caused by expression of distinct mRNAs.

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7 January 2021

A new rat type I-like alveolar epithelial cell line R3/1: bleomycin effects on caveolin expression

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7 January 2021

Activated cardiac adenosine A(1) receptors translocate out of caveolae

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7 January 2021

Up-regulation of caveolae and caveolar constituents in multidrug-resistant cancer cells

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7 January 2021

Upregulation of caveolin in multidrug resistant cancer cells: functional implications

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7 January 2021

Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells

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7 January 2021

Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases

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7 January 2021

Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease

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7 January 2021

Caveolin-1 expression enhances endothelial capillary tubule formation

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7 January 2021

Role of caveolae in signal-transducing function of cardiac Na+/K+-ATPase.

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7 January 2021

Tissue factor pathway inhibitor in endothelial cells colocalizes with glycolipid microdomains/caveolae. Regulatory mechanism(s) of the anticoagulant properties of the endothelium

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7 January 2021

Decreased endothelial nitric-oxide synthase (eNOS) activity resulting from abnormal interaction between eNOS and its regulatory proteins in hypoxia-induced pulmonary hypertension

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7 January 2021

Pulmonary lipid phosphate phosphohydrolase in plasma membrane signalling platforms

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7 January 2021

Caveolin and its cellular and subcellular immunolocalisation in lung alveolar epithelium: implications for alveolar epithelial type I cell function.

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7 January 2021

Segregation of heterotrimeric G proteins in cell surface microdomains. G(q) binds caveolin to concentrate in caveolae, whereas G(i) and G(s) target lipid rafts by default

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7 January 2021

Overexpression of P104L mutant caveolin-3 in mice develops hypertrophic cardiomyopathy with enhanced contractility in association with increased endothelial nitric oxide synthase activity

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7 January 2021

Downregulation of caveolin by chronic beta-adrenergic receptor stimulation in mice.

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7 January 2021

Caveolar compartmentation of caspase-3 in cardiac endothelial cells

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7 January 2021

Compositional changes in lipid microdomains of air-blood barrier plasma membranes in pulmonary interstitial edema

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7 January 2021

Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype.

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7 January 2021

Up-regulation of caveolin attenuates epidermal growth factor signaling in senescent cells

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7 January 2021

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7 January 2021

Differential regulation of nitric oxide synthases and their allosteric regulators in heart and vessels of hypertensive rats

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7 January 2021

Decreased expression of myocardial eNOS and caveolin in dogs with hypertrophic cardiomyopathy

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7 January 2021

Reduction of caveolin 1 gene expression in lung carcinoma cell lines

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7 January 2021

The alpha-isoform of caveolin-1 is a marker of vasculogenesis in early lung development

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7 January 2021

Caveolin-1 and -3 dissociations from caveolae to cytosol in the heart during aging and after myocardial infarction in rat

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7 January 2021

Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae

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7 January 2021

In situ flow activates endothelial nitric oxide synthase in luminal caveolae of endothelium with rapid caveolin dissociation and calmodulin association

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7 January 2021

Recruitment of endothelial caveolae into mechanotransduction pathways by flow conditioning in vitro

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7 January 2021

Differential targeting of beta -adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae. A mechanism to functionally regulate the cAMP signaling pathway

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7 January 2021

Activated protein kinase C isoforms target to cardiomyocyte caveolae : stimulation of local protein phosphorylation

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7 January 2021

Endothelial caveolae have the molecular transport machinery for vesicle budding, docking, and fusion including VAMP, NSF, SNAP, annexins, and GTPases

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7 January 2021

Aquaporin-1 in plasma membrane and caveolae provides mercury-sensitive water channels across lung endothelium

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7 January 2021

Caveolae from luminal plasmalemma of rat lung endothelium: microdomains enriched in caveolin, Ca(2+)-ATPase, and inositol trisphosphate receptor

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7 January 2021

Caveolae-deficient Endothelial Cells Show Defects in the Uptake and Transport of Albuminin Vivo

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7 January 2021

Microvascular hyperpermeability in caveolin-1 (-/-) knock-out mice. Treatment with a specific nitric-oxide synthase inhibitor, L-NAME, restores normal microvascular permeability in Cav-1 null mice

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7 January 2021

Interactions of STAT3 with caveolin-1 and heat shock protein 90 in plasma membrane raft and cytosolic complexes. Preservation of cytokine signaling during fever

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7 January 2021

Chronic myocardial hypoxia increases nitric oxide synthase and decreases caveolin-3.

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7 January 2021

Unexpectedly strong binding of a large metal ion (Bi3+) to human serum transferrin

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7 January 2021

Different roles for caveolin-1 in the development of non-small cell lung cancer versus small cell lung cancer

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7 January 2021

Impact of caveolin-1 expression on prognosis of pancreatic ductal adenocarcinoma

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7 January 2021

Caveolin-1 is regulated by c-myc and suppresses c-myc-induced apoptosis

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7 January 2021

Gp60 Activation Mediates Albumin Transcytosis in Endothelial Cells by Tyrosine Kinase-dependent Pathway

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7 January 2021

Mechanical unloading increases caveolin expression in the failing human heart.

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7 January 2021

Caveolin-1 is down-regulated in human ovarian carcinoma and acts as a candidate tumor suppressor gene

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7 January 2021

Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomas

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7 January 2021

Identification of differentially expressed genes in pulmonary adenocarcinoma by using cDNA array

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7 January 2021

Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice

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7 January 2021

Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade

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7 January 2021

Caveolar localization dictates physiologic signaling of beta 2-adrenoceptors in neonatal cardiac myocytes

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7 January 2021

Caveolin is an inhibitor of platelet-derived growth factor receptor signaling

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7 January 2021

Upregulation of caveolin-1 and caveolae organelles in Taxol-resistant A549 cells

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7 January 2021

Localization of cardiac sodium channels in caveolin-rich membrane domains: regulation of sodium current amplitude

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7 January 2021

Expression of caveolin-1 is associated with poor prognosis of patients with squamous cell carcinoma of the lung

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7 January 2021

Caveolin-1 peptide exerts cardioprotective effects in myocardial ischemia-reperfusion via nitric oxide mechanism

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7 January 2021

Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1.

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7 January 2021

Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice

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7 January 2021

Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide

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7 January 2021