Mutation of Ha-Ras C Terminus Changes Effector Pathway Utilization (Q57371882)

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Regulation of interaction of ras p21 with RalGDS and Raf-1 by cyclic AMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Mammalian Ras interacts directly with the serine/threonine kinase Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Increasing complexity of Ras signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Signal transduction from multiple Ras effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Protein prenylation: molecular mechanisms and functional consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

N-terminally myristoylated Ras proteins require palmitoylation or a polybasic domain for plasma membrane localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Palmitoylation of Ha-Ras facilitates membrane binding, activation of downstream effectors, and meiotic maturation in Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Cysteine-rich region of Raf-1 interacts with activator domain of post-translationally modified Ha-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Two distinct Raf domains mediate interaction with Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Farnesylation of Ras is important for the interaction with phosphoinositide 3-kinase gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Ras membrane targeting is essential for glucose signaling but not for viability in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

The effect of posttranslational modifications on the interaction of Ras2 with adenylyl cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

A non-farnesylated Ha-Ras protein can be palmitoylated and trigger potent differentiation and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Rho family GTPases and neuronal growth cone remodelling: relationship between increased complexity induced by Cdc42Hs, Rac1, and acetylcholine and collapse induced by RhoA and lysophosphatidic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Activation of the cellular proto-oncogene product p21Ras by addition of a myristylation signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Angiotensin II stimulates ERK via two pathways in epithelial cells: protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Activated N-ras gene induces neuronal differentiation of PC12 rat pheochromocytoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Simplified proteins: minimalist solutions to the 'protein folding problem'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

An essential role for Rac in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

A role for Rho in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Identification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: control of neuronal morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

The structural basis of the activation of Ras by Sos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

The isolation and characterization of cDNA encoding human and rat brain inositol polyphosphate 4-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Lipid-dependent Targeting of G Proteins into Rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Role of lipid modifications in targeting proteins to detergent-resistant membrane rafts. Many raft proteins are acylated, while few are prenylated.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Binding of basic peptides to membranes produces lateral domains enriched in the acidic lipids phosphatidylserine and phosphatidylinositol 4,5-bisphosphate: an electrostatic model and experimental results

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Signalling through the lipid products of phosphoinositide-3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Bioorganic synthesis of lipid-modified proteins for the study of signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Transient palmitoylation supports H-Ras membrane binding but only partial biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

The strength of interaction at the Raf cysteine-rich domain is a critical determinant of response of Raf to Ras family small GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Activity of plasma membrane-recruited Raf-1 is regulated by Ras via the Raf zinc finger

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Cholesterol and sphingolipid enhance the Triton X-100 insolubility of glycosylphosphatidylinositol-anchored proteins by promoting the formation of detergent-insoluble ordered membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Phosphoinositide 3-kinase-dependent and -independent activation of the small GTPase Rac2 in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200

Localization of epidermal growth factor-stimulated Ras/Raf-1 interaction to caveolae membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001368200