Inhibition of Ubiquitin-Specific Proteases as a Novel Anticancer Therapeutic Strategy (Q57490982)

2

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Meidan Ying

3

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Ji Cao

4

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Qiaojun He

5

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Hong Zhu

6

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Bo Yang

Frontiers in Pharmacology

7

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language of work or name

English

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publication date

2018

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published in

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volume

9

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page(s)

1080

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copyright license

Creative Commons Attribution 4.0 International

start time

27 September 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models

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USP14 de-ubiquitinates vimentin and miR-320a modulates USP14 and vimentin to contribute to malignancy in gastric cancer cells

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Decision for cell fate: deubiquitinating enzymes in cell cycle checkpoint

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Downregulation of ubiquitin-specific protease 14 (USP14) inhibits breast cancer cell proliferation and metastasis, but promotes apoptosis

2 November 2018

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Inhibition of proteasome deubiquitinase activity: a strategy to overcome resistance to conventional proteasome inhibitors?

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Ubiquitin-specific proteases as therapeutic targets for the treatment of breast cancer

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Deubiquitinases and the new therapeutic opportunities offered to cancer

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USP7 overexpression predicts a poor prognosis in lung squamous cell carcinoma and large cell carcinoma

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Deubiquitinase inhibition as a cancer therapeutic strategy

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Parkin-mediated K63-polyubiquitination targets ubiquitin C-terminal hydrolase L1 for degradation by the autophagy-lysosome system

2 November 2018

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A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance

2 November 2018

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USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis

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Over-expression of deubiquitinating enzyme USP14 in lung adenocarcinoma promotes proliferation through the accumulation of β-catenin

2 November 2018

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Expression of HAUSP in gliomas correlates with disease progression and survival of patients

2 November 2018

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A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance

2 November 2018

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2 November 2018

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The ubiquitin-specific protease USP2a enhances tumor progression by targeting cyclin A1 in bladder cancer

2 November 2018

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USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma

2 November 2018

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Inhibition of proteasome deubiquitinating activity as a new cancer therapy

2 November 2018

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Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13

2 November 2018

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USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma

2 November 2018

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DUB-le Trouble for Cell Survival

2 November 2018

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USP10 regulates p53 localization and stability by deubiquitinating p53

2 November 2018

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Emerging roles of deubiquitinases in cancer-associated pathways

2 November 2018

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2 November 2018

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Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells

2 November 2018

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Breaking the chains: structure and function of the deubiquitinases

2 November 2018

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2 November 2018

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A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway

2 November 2018

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Regulation of monoubiquitinated PCNA by DUB autocleavage

2 November 2018

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2 November 2018

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The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway

2 November 2018

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