PKC-θ: hitting the bull's eye (Q57961999)

Three-dimensional segregation of supramolecular activation clusters in T cells

21 January 2018

1 reference

Protein kinase C theta is critical for the development of in vivo T helper (Th)2 cell but not Th1 cell responses

21 January 2018

1 reference

PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice

21 January 2018

1 reference

A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28

21 January 2018

1 reference

The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells

21 January 2018

1 reference

CARMA1, BCL-10 and MALT1 in lymphocyte development and activation.

21 January 2018

1 reference

Protein kinase C-theta mediates negative feedback on regulatory T cell function

21 January 2018

1 reference

Antigen-independent signalosome of CARMA1, PKCθ, and TNF receptor-associated factor 2 (TRAF2) determines NF-κB signaling in T cells

21 January 2018

1 reference

CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse

21 January 2018

1 reference

Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation

21 January 2018

1 reference

T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase C theta

21 January 2018

1 reference

The SH2 domain is required for stable phosphorylation of p56lck at tyrosine 505, the negative regulatory site

21 January 2018

1 reference

Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines

21 January 2018

1 reference

A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation

21 January 2018

1 reference

Dynamics of subsynaptic vesicles and surface microclusters at the immunological synapse

21 January 2018

1 reference

PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation

21 January 2018

1 reference

Signaling by the germinal center kinase family of protein kinases

21 January 2018

1 reference

Ste20-type kinases: evolutionarily conserved regulators of ion transport and cell volume.

21 January 2018

1 reference

The Gads (GrpL) adaptor protein regulates T cell homeostasis

21 January 2018

1 reference

A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling

21 January 2018

1 reference

Differential requirement of PKC-theta in the development and function of natural regulatory T cells

21 January 2018

1 reference

Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling

21 January 2018

1 reference

T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

21 January 2018

1 reference

Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster

21 January 2018

1 reference

Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response

21 January 2018

1 reference

Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells

21 January 2018

1 reference

12 December 2020

The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity

1 reference

12 December 2020

Novel redistribution of an intracellular pool of CD45 accompanies T cell activation

1 reference

12 December 2020

Differential expression of a novel protein kinase in human B lymphocytes. Preferential localization in the germinal center

1 reference

12 December 2020

Mice deficient in PKC theta demonstrate impaired in vivo T cell activation and protection from T cell-mediated inflammatory diseases

1 reference

12 December 2020

Phosphorylation of the protein kinase C-theta activation loop and hydrophobic motif regulates its kinase activity, but only activation loop phosphorylation is critical to in vivo nuclear-factor-kappaB induction

1 reference

12 December 2020