Eag1 as a cancer target (Q58212558)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18554152%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

review article

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title

Eag1 as a cancer target (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18554152%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1

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9 January 2020

author name string

Walter Sühmer

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18554152%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

English

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publication date

1 July 2008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18554152%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

9 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18554152%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

volume

12

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9 January 2020

issue

7

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9 January 2020

page(s)

837-843

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18554152%20AND%20SRC:MED&resulttype=core&format=json

Voltage-gated K+ channels in human T lymphocytes: a role in mitogenesis?

9 January 2020

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Potassium channels are a new target field in anticancer drug design

21 January 2018

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Voltage-gated ion channels, new targets in anti-cancer research.

21 January 2018

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Potassium channels as tumour markers

21 January 2018

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Ether à go-go potassium channels and cancer

21 January 2018

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Role of voltage-gated potassium channels in cancer.

21 January 2018

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21 January 2018

Ion channels and cancer

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A distinct potassium channel polypeptide encoded by the Drosophila eag locus.

21 January 2018

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Alteration of four identified K+ currents in Drosophila muscle by mutations in eag.

21 January 2018

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Ether-à-go-go encodes a voltage-gated channel permeable to K+ and Ca2+ and modulated by cAMP.

21 January 2018

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The eag family of K+ channels in Drosophila and mammals

21 January 2018

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International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels

21 January 2018

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Physiology of EAG K+ channels

21 January 2018

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Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain

21 January 2018

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Inhibition of human ether à go-go potassium channels by Ca(2+)/calmodulin

21 January 2018

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C-terminal domains implicated in the functional surface expression of potassium channels

21 January 2018

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Interaction of the K channel beta subunit, Hyperkinetic, with eag family members

21 January 2018

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Purification of an EH domain-binding protein from rat brain that modulates the gating of the rat ether-à-go-go channel

21 January 2018

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Slob, a novel protein that interacts with the Slowpoke calcium-dependent potassium channel

21 January 2018

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KCR1, a membrane protein that facilitates functional expression of non-inactivating K+ currents associates with rat EAG voltage-dependent K+ channels

21 January 2018

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Elevation of intracellular calcium by muscarinic receptor activation induces a block of voltage-activated rat ether-à-go-go channels in a stably transfected cell line

21 January 2018

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Inhibition of human ether à go-go potassium channels by Ca2+/calmodulin binding to the cytosolic N- and C-termini

21 January 2018

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Cloning and functional expression of rat eag2, a new member of the ether-à-go-go family of potassium channels and comparison of its distribution with that of eag1.

21 January 2018

1 reference

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Molecular identification and characterisation of the human eag2 potassium channel

21 January 2018

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Functional distinction of human EAG1 and EAG2 potassium channels

21 January 2018

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Extracellular Mg2+ regulates activation of rat eag potassium channel.

21 January 2018

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The roles of intracellular regions in the activation of voltage-dependent potassium channels

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.12.7.837

Glycosylation of Eag1 (Kv10.1) potassium channels: intracellular trafficking and functional consequences

21 January 2018

1 reference

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An ether -à-go-go K+ current, Ih-eag, contributes to the hyperpolarization of human fusion-competent myoblasts.

21 January 2018

1 reference

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Role of an inward rectifier K+ current and of hyperpolarization in human myoblast fusion

21 January 2018

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Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion

21 January 2018

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Oncogenic potential of EAG K(+) channels

21 January 2018

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Overexpression of Eag1 potassium channels in clinical tumours.

21 January 2018

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K+ channel expression in human breast cancer cells: involvement in cell cycle regulation and carcinogenesis

21 January 2018

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Ether à go-go potassium channel expression in soft tissue sarcoma patients

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.12.7.837

Ether a go-go potassium channels as human cervical cancer markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.7.837

Aberrant expression of Eag1 potassium channels in gastric cancer patients and cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.7.837

Functional up-regulation of HERG K+ channels in neoplastic hematopoietic cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.12.7.837

Expression of ether à go-go potassium channels in human gliomas.

21 January 2018

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Mitosis-promoting factor-mediated suppression of a cloned delayed rectifier potassium channel expressed in Xenopus oocytes

21 January 2018

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21 January 2018

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Cytoskeletal interactions determine the electrophysiological properties of human EAG potassium channels.

21 January 2018

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IGF-1 activates hEAG K(+) channels through an Akt-dependent signaling pathway in breast cancer cells: role in cell proliferation

21 January 2018

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Silencing the activity and proliferative properties of the human EagI Potassium Channel by RNA Interference

21 January 2018

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Effect of extracellular matrix on adhesion, viability, actin cytoskeleton and K+ currents of cells expressing human ether à go-go channels.

21 January 2018

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Activation of hEAG1 potassium channels by arachidonic acid

21 January 2018

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Mechanism of block of hEag1 K+ channels by imipramine and astemizole

21 January 2018

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Effects of imipramine on ion channels and proliferation of IGR1 melanoma cells

21 January 2018

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Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole

21 January 2018

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Inhibition of the current of heterologously expressed HERG potassium channels by imipramine and amitriptyline

21 January 2018

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hERG potassium channels and cardiac arrhythmia

21 January 2018

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Generation of functional ion-channel tools by E3 targeting.

21 January 2018

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Monoclonal Antibody Blockade of the Human Eag1 Potassium Channel Function Exerts Antitumor Activity

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.12.7.837

Eag1: an emerging oncological target.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.7.837

A clinical drug library screen identifies astemizole as an antimalarial agent

21 January 2018

1 reference

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Antidepressant Medications and Risk for Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.7.837

Chronic variable stress facilitates tumoral growth: reversal by imipramine administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.7.837

Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.12.7.837

10.1517/14728222.12.7.837

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18554152%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference