Targeting Oncogene-Induced Autophagy: A New Approach in Cancer Therapy? (Q58919591)

April 2022 Public Data File from Crossref

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April 2022 Public Data File from Crossref

cites work

Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction

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https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagy: from phenomenology to molecular understanding in less than a decade

21 January 2018

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https://api.crossref.org/works/10.1155%2F2013%2F350863

Mammalian macroautophagy at a glance

21 January 2018

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https://api.crossref.org/works/10.1155%2F2013%2F350863

Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Pathogenic lysosomal depletion in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Oncogene-induced autophagy and the Goldilocks principle

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

The dynamic nature of autophagy in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

The double-edged sword of autophagy modulation in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

RAS oncogenes: weaving a tumorigenic web

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Targeting RAS signalling pathways in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Pancreatic cancers require autophagy for tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Oncogenic Ras-induced expression of Noxa and Beclin-1 promotes autophagic cell death and limits clonogenic survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagic activity dictates the cellular response to oncogenic RAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Tumor suppressors and cell metabolism: a recipe for cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

The autophagy conundrum in cancer: influence of tumorigenic metabolic reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Deconvoluting the context-dependent role for autophagy in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagy and cancer--issues we need to digest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Targeting autophagy addiction in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

c-myc induces autophagy in rat 3Y1 fibroblast cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

MYC on the path to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagy as a therapeutic target in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagy is a therapeutic target in anticancer drug resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagy and ionizing radiation in tumors: the "survive or not survive" dilemma

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagy contributes to resistance of tumor cells to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Bortezomib blocks Bax degradation in malignant B cells during treatment with TRAIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Targeting autophagy potentiates chemotherapy-induced apoptosis and proliferation inhibition in hepatocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

AMPK inhibitor compound C suppresses cell proliferation by induction of apoptosis and autophagy in human colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signalling in human hepatocellular carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Imatinib induces autophagy through BECLIN-1 and ATG5 genes in chronic myeloid leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagy inhibition and antimalarials promote cell death in gastrointestinal stromal tumor (GIST).

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

GX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Perifosine induces protective autophagy and upregulation of ATG5 in human chronic myelogenous leukemia cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagic cell death induced by resveratrol depends on the Ca(2+)/AMPK/mTOR pathway in A549 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

The role of reactive oxygen species and autophagy in safingol-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Safingol (L-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Induction of apoptosis and autophagy by sodium selenite in A549 human lung carcinoma cells through generation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Sodium selenite-induced activation of DAPK promotes autophagy in human leukemia HL60 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Temsirolimus downregulates p21 without altering cyclin D1 expression and induces autophagy and synergizes with vorinostat in mantle cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Inhibition of autophagy as a strategy to augment radiosensitization by the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Inhibition of autophagy at a late stage enhances imatinib-induced cytotoxicity in human malignant glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Methods for monitoring autophagy using GFP-LC3 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagy: assays and artifacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Targeting autophagy during cancer therapy to improve clinical outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Targeting the mTOR signaling network for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Beyond rapalog therapy: preclinical pharmacology and antitumor activity of WYE-125132, an ATP-competitive and specific inhibitor of mTORC1 and mTORC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Akt and autophagy cooperate to promote survival of drug-resistant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Targeting the PI3K/mTOR axis, alone and in combination with autophagy blockade, for the treatment of malignant peripheral nerve sheath tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagy inhibition sensitizes colon cancer cells to antiangiogenic and cytotoxic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Obatoclax and lapatinib interact to induce toxic autophagy through NOXA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Role of autophagy in cancer prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Hydroxychloroquine concentration-response relationships in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Principles and current strategies for targeting autophagy for cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Phase I trial, pharmacokinetics, and pharmacodynamics of vandetanib and dasatinib in children with newly diagnosed diffuse intrinsic pontine glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Combination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863

Autophagy inhibition for chemosensitization and radiosensitization in cancer: do the preclinical data support this therapeutic strategy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2013%2F350863