A CRISPR knockout screen identifies SETDB1-target retroelement silencing factors in embryonic stem cells (Q59348999)

Retroelement silencing factor 1

GOA release 2020-03-11

1 reference

Histone-lysine N-methyltransferase SETDB1

GOA release 2020-03-11

1 reference

Versatile retroviral vectors for potential use in gene therapy

GOA release 2020-03-11

1 reference

Kei Fukuda

1

0 references

Akihiko Okuda

series ordinal

2

0 references

Kosuke Yusa

series ordinal

3

0 references

Yoichi Shinkai

series ordinal

4

0 references

language of work or name

English

0 references

publication date

June 2018

0 references

published in

Genome Research

0 references

volume

28

0 references

issue

6

0 references

page(s)

846-858

0 references

cites work

1 reference

12 December 2020

Cell cycle-dependent localization of macroH2A in chromatin of the inactive X chromosome

1 reference

12 December 2020

Initial sequencing and comparative analysis of the mouse genome

1 reference

12 December 2020

mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression

1 reference

12 December 2020

Mobile elements: drivers of genome evolution

1 reference

12 December 2020

Shelterin: the protein complex that shapes and safeguards human telomeres

1 reference

12 December 2020

Retroviral elements and their hosts: insertional mutagenesis in the mouse germ line

1 reference

12 December 2020

FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin

1 reference

12 December 2020

Transposable elements and the epigenetic regulation of the genome

1 reference

12 December 2020

PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing

1 reference

12 December 2020

How shelterin protects mammalian telomeres

1 reference

12 December 2020

The telosome/shelterin complex and its functions

1 reference

12 December 2020

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

1 reference

12 December 2020

SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity

1 reference

12 December 2020

Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells

1 reference

12 December 2020

Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells

1 reference

12 December 2020

KAP1 controls endogenous retroviruses in embryonic stem cells

1 reference

12 December 2020

Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX.

1 reference

12 December 2020

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.

1 reference

12 December 2020

Mobilizing diversity: transposable element insertions in genetic variation and disease

1 reference

12 December 2020

DNA methylation and SETDB1/H3K9me3 regulate predominantly distinct sets of genes, retroelements, and chimeric transcripts in mESCs

1 reference

12 December 2020

Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation.

1 reference

12 December 2020

Indefinite self-renewal of ESCs through Myc/Max transcriptional complex-independent mechanisms.

1 reference

12 December 2020

H3K9me3-binding proteins are dispensable for SETDB1/H3K9me3-dependent retroviral silencing

1 reference

12 December 2020

Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency

1 reference

12 December 2020

MORC family ATPases required for heterochromatin condensation and gene silencing.

1 reference

12 December 2020

Microarray analysis of LTR retrotransposon silencing identifies Hdac1 as a regulator of retrotransposon expression in mouse embryonic stem cells

1 reference

12 December 2020

Active transposition in genomes

1 reference

12 December 2020

MORC2 signaling integrates phosphorylation-dependent, ATPase-coupled chromatin remodeling during the DNA damage response

1 reference

12 December 2020

Multiplex genome engineering using CRISPR/Cas systems

1 reference

12 December 2020

RNA-guided human genome engineering via Cas9

1 reference

12 December 2020

BRG1 is required for formation of senescence-associated heterochromatin foci induced by oncogenic RAS or BRCA1 loss

1 reference

12 December 2020

Proviral silencing in embryonic cells is regulated by Yin Yang 1.

1 reference

12 December 2020

Genetic screens in human cells using the CRISPR-Cas9 system

1 reference

12 December 2020

Genome-scale CRISPR-Cas9 knockout screening in human cells

1 reference

12 December 2020

Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

1 reference

12 December 2020

DBTMEE: a database of transcriptome in mouse early embryos

1 reference

12 December 2020

MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens

1 reference

12 December 2020

MORC1 represses transposable elements in the mouse male germline

1 reference

12 December 2020

hnRNP K coordinates transcriptional silencing by SETDB1 in embryonic stem cells

1 reference

12 December 2020

The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses

1 reference

12 December 2020

ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes.

1 reference

12 December 2020

Histone H3.3 is required for endogenous retroviral element silencing in embryonic stem cells

1 reference

12 December 2020

Atrx promotes heterochromatin formation at retrotransposons

1 reference

12 December 2020

GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells.

1 reference

12 December 2020

By recruiting HDAC1, MORC2 suppresses p21 Waf1/Cip1 in gastric cancer

1 reference

12 December 2020

Mammalian Endogenous Retroviruses

1 reference

12 December 2020

Systematic identification of factors for provirus silencing in embryonic stem cells

1 reference

12 December 2020

Identification and characterization of essential genes in the human genome.

1 reference

12 December 2020

Histone chaperone CAF-1 mediates repressive histone modifications to protect preimplantation mouse embryos from endogenous retrotransposons

1 reference

12 December 2020

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.

1 reference

12 December 2020

Arabidopsis AtMORC4 and AtMORC7 Form Nuclear Bodies and Repress a Large Number of Protein-Coding Genes

1 reference

12 December 2020

Taz1-Shelterin Promotes Facultative Heterochromatin Assembly at Chromosome-Internal Sites Containing Late Replication Origins.

1 reference

12 December 2020

Restricting retrotransposons: a review

1 reference

12 December 2020

Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.

1 reference

12 December 2020

MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs

1 reference

12 December 2020

ATF7IP-Mediated Stabilization of the Histone Methyltransferase SETDB1 Is Essential for Heterochromatin Formation by the HUSH Complex

1 reference

12 December 2020

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.

1 reference

12 December 2020

Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2.

1 reference

12 December 2020

Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators

1 reference

12 December 2020