IL-21 Enhances Antitumor Responses without Stimulating Proliferation of Malignant T Cells of Patients with Sézary Syndrome (Q60711900)

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3 January 2020

title

IL-21 enhances antitumor responses without stimulating proliferation of malignant T cells of patients with Sézary syndrome (English)

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3 January 2020

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Maria Wysocka

3

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3 January 2020

Monika Kasprzycka

9

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Jessica S Yoon

1

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3 January 2020

Sarah M Newton

2

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3 January 2020

Stephen D Hess

5

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3 January 2020

Stephen K Richardson

6

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Julie H Lin

7

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Bernice M Benoit

8

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3 January 2020

Alain H Rook

11

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language of work or name

English

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publication date

23 August 2007

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Journal of Investigative Dermatology

3 January 2020

published in

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volume

128

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3 January 2020

issue

2

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page(s)

473-480

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A clonal CD4-positive T-cell line established from the blood of a patient with Sézary syndrome

3 January 2020

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IL-21 sustains CD28 expression on IL-15-activated human naive CD8+ T cells.

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Circulating natural killer lymphocytes are potential cytotoxic effectors against autologous malignant cells in sezary syndrome patients

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IL-21 induces the functional maturation of murine NK cells

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IL-21 activates both innate and adaptive immunity to generate potent antitumor responses that require perforin but are independent of IFN-gamma

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