Epidermal Growth Factor-induced DNA Synthesis (Q62604103)

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15 December 2019

title

Epidermal growth factor-induced DNA synthesis. Key role for Src phosphorylation of the docking protein Gab2 (English)

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15 December 2019

2

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15 December 2019

author name string

Mei Kong

series ordinal

1

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15 December 2019

Victor Dumas

series ordinal

3

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15 December 2019

Barry I Posner

series ordinal

4

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15 December 2019

language of work or name

English

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publication date

2 December 2002

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Journal of Biological Chemistry

15 December 2019

number of pages

8

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based on heuristic

inferred from page(s)

published in

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15 December 2019

volume

278

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15 December 2019

issue

8

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15 December 2019

page(s)

5837-5844

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Signal transduction by receptors with tyrosine kinase activity

15 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

The epidermal growth factor

21 January 2018

1 reference

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Epidermal growth factor receptor-mediated motility in fibroblasts

21 January 2018

1 reference

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EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.

21 January 2018

1 reference

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Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src

21 January 2018

1 reference

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pp60c-src tyrosine kinase, myristylation, and modulatory domains are required for enhanced mitogenic responsiveness to epidermal growth factor seen in cells overexpressing c-src

21 January 2018

1 reference

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Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

The Src SH3 domain is required for DNA synthesis induced by platelet-derived growth factor and epidermal growth factor

21 January 2018

1 reference

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Gab-1-mediated IGF-1 signaling in IRS-1-deficient 3T3 fibroblasts

21 January 2018

1 reference

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Epidermal growth factor-induced phosphatidylinositol 3-kinase activation and DNA synthesis. Identification of Grb2-associated binder 2 as the major mediator in rat hepatocytes

21 January 2018

1 reference

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The IRS-signalling system: a network of docking proteins that mediate insulin action

21 January 2018

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The role of membrane-associated adaptors in T cell receptor signalling

21 January 2018

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21 January 2018

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Gab2 is phosphorylated on tyrosine upon interleukin-2/interleukin-15 stimulation in mycosis-fungoides-derived tumor T cells and associates inducibly with SHP-2 and Stat5a

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules

21 January 2018

1 reference

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Structure and function of phosphoinositide 3-kinases.

21 January 2018

1 reference

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Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

21 January 2018

1 reference

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Identification of a novel protein tyrosine kinase that phosphorylates pp60c-src and regulates its activity in neonatal rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Constitutive activation of Src family kinases in mouse embryos that lack Csk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Crystal structures of c-Src reveal features of its autoinhibitory mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Requirement of SHP2 binding to Grb2-associated binder-1 for mitogen-activated protein kinase activation in response to lysophosphatidic acid and epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Phosphotyrosines 627 and 659 of Gab1 constitute a bisphosphoryl tyrosine-based activation motif (BTAM) conferring binding and activation of SHP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

A novel positive feedback loop mediated by the docking protein Gab1 and phosphatidylinositol 3-kinase in epidermal growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

A conserved inositol phospholipid binding site within the pleckstrin homology domain of the Gab1 docking protein is required for epithelial morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Inhibition of Src family kinases blocks epidermal growth factor (EGF)-induced activation of Akt, phosphorylation of c-Cbl, and ubiquitination of the EGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Beta-adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Gab2, a new pleckstrin homology domain-containing adapter protein, acts to uncouple signaling from ERK kinase to Elk-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Synapsin I interacts with c-Src and stimulates its tyrosine kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

SH2 domains recognize specific phosphopeptide sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Cellular functions regulated by Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Src transduces erythropoietin-induced differentiation signals through phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Scaffolding protein Gab2 mediates differentiation signaling downstream of Fms receptor tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208286200

Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M208286200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12464621%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

1 reference