Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23 (Q62658162)

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title

Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23 (English)

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author name string

Rubén Martínez-Barricarte

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English

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publication date

1 December 2018

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volume

3

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issue

30

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Stable growth transformation of human T lymphocytes by herpesvirus saimiri

15 April 2020

page(s)

eaau6759

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cites work

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Bacillus Calmette Guérin triggers the IL-12/IFN-γ axis by an IRAK-4- and NEMO-dependent, non-cognate interaction between monocytes, NK, and T lymphocytes

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Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs

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Molecular complementation of IL-12Rbeta1 deficiency reveals functional differences between IL-12Rbeta1 alleles including partial IL-12Rbeta1 deficiency

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Whole-exome sequencing-based discovery of STIM1 deficiency in a child with fatal classic Kaposi sarcoma

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Revisiting human IL-12Rβ1 deficiency: a survey of 141 patients from 30 countries

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Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity

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IL-12Rβ1 deficiency in two of fifty children with severe tuberculosis from Iran, Morocco, and Turkey

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Accounting for genetic heterogeneity in homozygosity mapping: application to Mendelian susceptibility to mycobacterial disease

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IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung

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Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency

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Functional STAT3 deficiency compromises the generation of human T follicular helper cells.

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A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3

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An integrated map of genetic variation from 1,092 human genomes

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SnIPRE: selection inference using a Poisson random effects model

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Inherited IL-12p40 deficiency: genetic, immunologic, and clinical features of 49 patients from 30 kindreds

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IL-12Rβ1 deficiency: mutation update and description of the IL12RB1 variation database

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Differential expression and function of human IL-12Rβ2 polymorphic variants

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12 December 2020

Partial IFN-γR2 deficiency is due to protein misfolding and can be rescued by inhibitors of glycosylation

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12 December 2020

Genic intolerance to functional variation and the interpretation of personal genomes

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12 December 2020

An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis

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Clinical features of Candidiasis in patients with inherited interleukin 12 receptor β1 deficiency

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A general framework for estimating the relative pathogenicity of human genetic variants

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The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation

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MHC class I and II deficiencies

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Mendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of inborn errors of IFN-γ immunity

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Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis

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STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function

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IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases.

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IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations

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A side-by-side comparison of T cell reactivity to fifty-nine Mycobacterium tuberculosis antigens in diverse populations from five continents

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Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome

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The burgeoning family of unconventional T cells

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The human gene damage index as a gene-level approach to prioritizing exome variants

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Genomic Signatures of Selective Pressures and Introgression from Archaic Hominins at Human Innate Immunity Genes

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The mutation significance cutoff: gene-level thresholds for variant predictions

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Heterogeneity of Human CD4(+) T Cells Against Microbes

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Whole-exome sequencing to analyze population structure, parental inbreeding, and familial linkage

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Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasis.

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Evidence of innate lymphoid cell redundancy in humans

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Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency

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Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency

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Inborn errors of immunity underlying fungal diseases in otherwise healthy individuals

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Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1.

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12 December 2020

10.1126/SCIIMMUNOL.AAU6759

Identifiers

DOI

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15 April 2020

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15 April 2020

PubMed publication ID

30578351

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