Safety, tolerability, pharmacokinetics, and immunogenicity of the therapeutic monoclonal antibody mAb114 targeting Ebola virus glycoprotein (VRC 608): an open-label phase 1 study (Q64360391)

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article by Martin R Gaudinski et al published 2 March 2019 in The Lancet

Language	Label	Description	Also known as
English	Safety, tolerability, pharmacokinetics, and immunogenicity of the therapeutic monoclonal antibody mAb114 targeting Ebola virus glycoprotein (VRC 608): an open-label phase 1 study	article by Martin R Gaudinski et al published 2 March 2019 in The Lancet

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scholarly article

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Safety, tolerability, pharmacokinetics, and immunogenicity of the therapeutic monoclonal antibody mAb114 targeting Ebola virus glycoprotein (VRC 608): an open-label phase 1 study (English)

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Orthoebolavirus zairense

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pharmacokinetics

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Barney S. Graham

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Barney S Graham

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Julie Ledgerwood

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Julie E Ledgerwood

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Adrian B. McDermott

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Adrian McDermott

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John R. Mascola

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John R Mascola

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Ingelise J Gordon

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Ingelise J Gordon

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Richard A Koup

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Alicia T. Widge

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Alicia Widge

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Nancy J Sullivan

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LaSonji A. Holman

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LaSonji A Holman

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Martha Nason

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Martin R Gaudinski

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Martin R Gaudinski

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Laura Novik

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Nina M. Berkowitz

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Nina Berkowitz

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Galina V Yamshchikov

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Galina Yamshchikov

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John Misasi

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Charla A Andrews

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Charla Andrews

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Edmund Capparelli

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Edmund Capparelli

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Katherine V Houser

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Katherine V Houser

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Sandra Sitar

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Carolyn Laurencot

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Carolyn Laurencot

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Emily E Coates

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Cristina A Carter

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Cristina Carter

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Kevin Carlton

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Eugeania Burch

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Grace L Chen

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Sandra Vazquez

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Frank Arnold

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Heather Lawlor

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Jason Gall

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Robert T Bailer

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publication date

2 March 2019

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393

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10174

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889-898

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Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequence analysis of the Ebola virus genome: organization, genetic elements, and comparison with the genome of Marburg virus

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https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Exotic emerging viral diseases: progress and challenges

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

7 January 2021

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Global Aspects of Emerging and Potential Zoonoses: a WHO Perspective

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https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

7 January 2021

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inferred from DOI database lookup

An outbreak of Ebola in Uganda

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Assessment of the risk of Ebola virus transmission from bodily fluids and fomites

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Treatment of Ebola hemorrhagic fever with blood transfusions from convalescent patients. International Scientific and Technical Committee

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https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of Convalescent Plasma for Ebola Virus Disease in Guinea

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of convalescent whole blood for treating Ebola Virus Disease in Freetown, Sierra Leone.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Ebola hemorrhagic fever: evaluation of passive immunotherapy in nonhuman primates

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Postexposure antibody prophylaxis protects nonhuman primates from filovirus disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

7 January 2021

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inferred from DOI database lookup

CD8+ cellular immunity mediates rAd5 vaccine protection against Ebola virus infection of nonhuman primates

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https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Reversion of advanced Ebola virus disease in nonhuman primates with ZMapp

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

7 January 2021

based on heuristic

inferred from DOI database lookup

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https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice

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7 January 2021

based on heuristic

inferred from DOI database lookup

Safety, pharmacokinetics, and immunogenicity of a co-formulated cocktail of three human monoclonal antibodies targeting Ebola virus glycoprotein in healthy adults: a randomised, first-in-human phase 1 study

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7 January 2021

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inferred from DOI database lookup

A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection

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7 January 2021

based on heuristic

inferred from DOI database lookup

Ebola Immunity: Gaining a Winning Position in Lightning Chess

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7 January 2021

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inferred from DOI database lookup

Structural and molecular basis for Ebola virus neutralization by protective human antibodies

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https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

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inferred from DOI database lookup

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https://api.crossref.org/works/10.1016%2FS0140-6736%2819%2930036-4

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Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences

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7 January 2021

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Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

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inferred from DOI database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/30686586

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inferred from PubMed ID database lookup

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https://pubmed.ncbi.nlm.nih.gov/30686586

12 December 2020

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10.1016/S0140-6736(19)30036-4

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