Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide (Q64379397)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301943%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301943%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301943%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Minna Woo

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301943%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

Y J Park

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301943%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

S Lee

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301943%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

T J Kieffer

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301943%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

G L Warnock

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301943%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

M Speck

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301943%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Z Hao

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301943%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

L Marzban

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301943%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

1 February 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301943%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22301943%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00125-012-2451-2

22 January 2020

exact match

0 references

cites work

Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.

1 reference

12 December 2020

Islet amyloid polypeptide, islet amyloid, and diabetes mellitus

1 reference

12 December 2020

Widespread amyloid deposition in transplanted human pancreatic islets

1 reference

12 December 2020

Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis

1 reference

12 December 2020

β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency

1 reference

12 December 2020

IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.

1 reference

12 December 2020

Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture

1 reference

12 December 2020

Rapid deposition of amyloid in human islets transplanted into nude mice.

1 reference

12 December 2020

Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts

1 reference

12 December 2020

Amylin-induced cytotoxicity is associated with activation of caspase-3 and MAP kinases

1 reference

12 December 2020

Islet amyloid polypeptide: pinpointing amino acid residues linked to amyloid fibril formation

1 reference

12 December 2020

Purification and characterization of a peptide from amyloid-rich pancreases of type 2 diabetic patients

1 reference

12 December 2020

Human islet amyloid polypeptide oligomers disrupt cell coupling, induce apoptosis, and impair insulin secretion in isolated human islets.

1 reference

12 December 2020

Aberrant processing of human proislet amyloid polypeptide results in increased amyloid formation

1 reference

12 December 2020

Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death

1 reference

12 December 2020

Insulitis in human type 1 diabetes

1 reference

12 December 2020

The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells

1 reference

12 December 2020

Amyloid formation results in recurrence of hyperglycaemia following transplantation of human IAPP transgenic mouse islets

1 reference

12 December 2020

Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

1 reference

12 December 2020

Deletion of Fas in the pancreatic beta-cells leads to enhanced insulin secretion

1 reference

12 December 2020

β-cell loss and β-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition

1 reference

12 December 2020

Glucose- and time-dependence of islet amyloid formation in vitro

1 reference

12 December 2020

The dual role of Fas-ligand as an injury effector and defense strategy in diabetes and islet transplantation

1 reference

12 December 2020

Donor islet endothelial cells participate in formation of functional vessels within pancreatic islet grafts

1 reference

12 December 2020

Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1.

1 reference

12 December 2020

Successful versus failed adaptation to high-fat diet-induced insulin resistance: the role of IAPP-induced beta-cell endoplasmic reticulum stress

1 reference

12 December 2020

Processing of pro-islet amyloid polypeptide in the constitutive and regulated secretory pathways of beta cells

1 reference

12 December 2020

Amyloid ion channels: a common structural link for protein-misfolding disease

1 reference

12 December 2020

Islet amyloid polypeptide demonstrates a persistent capacity to disrupt membrane integrity

1 reference

12 December 2020

1 reference

12 December 2020

Fas-associated death receptor signaling evoked by human amylin in islet beta-cells

1 reference

12 December 2020

Fas and Fas ligand expression in inflamed islets in pancreas sections of patients with recent-onset Type I diabetes mellitus

1 reference

12 December 2020

Calcium elevation in mouse pancreatic beta cells evoked by extracellular human islet amyloid polypeptide involves activation of the mechanosensitive ion channel TRPV4.

1 reference

12 December 2020

High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated beta-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes

1 reference

12 December 2020

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

1 reference

12 December 2020

Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets

1 reference

12 December 2020

Localization of the basement membrane heparan sulfate proteoglycan in islet amyloid deposits in type II diabetes mellitus

1 reference

12 December 2020

Prolonged exposure of pancreatic beta cells to raised glucose concentrations results in increased cellular content of islet amyloid polypeptide precursors

1 reference

12 December 2020

Serum levels of proamylin and amylin in normal subjects and patients with impaired glucose regulation and type 2 diabetes mellitus

1 reference

12 December 2020

Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis

1 reference

12 December 2020

Amyloid fibrils in human insulinoma and islets of Langerhans of the diabetic cat are derived from a neuropeptide-like protein also present in normal islet cells

1 reference

12 December 2020

Impaired proinsulin processing is a characteristic of transplanted islets

1 reference

12 December 2020

Regulation of CD95/APO-1/Fas-induced apoptosis by protein phosphatases

1 reference

12 December 2020

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

1 reference

12 December 2020

The role of Fas in autoimmune diabetes

1 reference

12 December 2020

Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets

1 reference

12 December 2020

Identification of a heparin binding domain in the N-terminal cleavage site of pro-islet amyloid polypeptide. Implications for islet amyloid formation

1 reference

12 December 2020

Differences between amyloid toxicity in alpha and beta cells in human and mouse islets and the role of caspase-3.

1 reference

12 December 2020

Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions

1 reference

12 December 2020

Differences in amyloid deposition in islets of transgenic mice expressing human islet amyloid polypeptide versus human islets implanted into nude mice

1 reference

12 December 2020