DNA damage-induced phosphorylation of p53 at serine 20 correlates with p21 and Mdm-2 induction in vivo (Q73434282)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175334%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

DNA damage-induced phosphorylation of p53 at serine 20 correlates with p21 and Mdm-2 induction in vivo (English)

1 reference

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3 November 2019

author name string

J R Jabbur

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175334%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

P Huang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175334%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

W Zhang

series ordinal

3

1 reference

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3 November 2019

language of work or name

English

0 references

publication date

1 December 2000

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3 November 2019

1 reference

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3 November 2019

volume

19

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3 November 2019

issue

54

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3 November 2019

page(s)

6203-6208

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1204017

3 November 2019

exact match

0 references

cites work

Regulation of p53 function and stability by phosphorylation

1 reference

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7 January 2021

Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

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7 January 2021

Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

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7 January 2021

Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

1 reference

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7 January 2021

mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Protein kinase CK1 is a p53-threonine 18 kinase which requires prior phosphorylation of serine 15

1 reference

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7 January 2021

Regulation of p53 downstream genes.

1 reference

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7 January 2021

The complexity of p53 modulation: emerging patterns from divergent signals

1 reference

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7 January 2021

Identification of a sequence element from p53 that signals for Mdm2-targeted degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Human p53 is phosphorylated on serines 6 and 9 in response to DNA damage-inducing agents

1 reference

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7 January 2021

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

1 reference

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7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

1 reference

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7 January 2021

RB regulates the stability and the apoptotic function of p53 via MDM2

1 reference

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7 January 2021

p38 kinase mediates UV-induced phosphorylation of p53 protein at serine 389.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

The p38MAPK inhibitor SB203580 alleviates ultraviolet-induced phosphorylation at serine 389 but not serine 15 and activation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Differential p53 phosphorylation and activation of apoptosis-promoting genes Bax and Fas/APO-1 by irradiation and ara-C treatment

1 reference

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7 January 2021

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Regulation of Mdm2-directed degradation by the C terminus of p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

1 reference

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7 January 2021

Phosphorylation of p53 serine 15 increases interaction with CBP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Human TAFII31 protein is a transcriptional coactivator of the p53 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Ultraviolet radiation, but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

p53 is phosphorylated in vitro and in vivo by an ultraviolet radiation-induced protein kinase characteristic of the c-Jun kinase, JNK1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Signaling to p53: breaking the MDM2-p53 circuit

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

DNA damage activates p53 through a phosphorylation-acetylation cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by a casein 1-like kinase. Effect on Mdm2 binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Phosphorylation of serine 392 stabilizes the tetramer formation of tumor suppressor protein p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

DNA damage induces phosphorylation of the amino terminus of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

A role for ATR in the DNA damage-induced phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

The alpha-helical FXXPhiPhi motif in p53: TAF interaction and discrimination by MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204017

7 January 2021

The p53-mdm-2 autoregulatory feedback loop

1 reference

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7 January 2021

A temperature-sensitive mutant of human p53.

1 reference

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7 January 2021