Differential graft-versus-leukaemia effect by CD28 and CD40 co-stimulatory blockade after graft-versus-host disease prophylaxis (Q74417602)

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10 November 2019

title

Differential graft-versus-leukaemia effect by CD28 and CD40 co-stimulatory blockade after graft-versus-host disease prophylaxis (English)

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10 November 2019

author name string

J Ohata

1

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10 November 2019

J Sakurai

2

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10 November 2019

K Saito

3

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10 November 2019

K Tani

4

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10 November 2019

S Asano

5

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10 November 2019

M Azuma

6

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10 November 2019

publication date

1 July 2002

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Clinical and Experimental Immunology

10 November 2019

published in

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10 November 2019

volume

129

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10 November 2019

issue

1

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10 November 2019

page(s)

61-68

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Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

10 November 2019

cites work

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12 December 2020

CD40 ligand blockade induces CD4+ T cell tolerance and linked suppression

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12 December 2020

Soluble antigen and CD40 triggering are sufficient to induce primary and memory cytotoxic T cells

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12 December 2020

Naive CD8+ T cells do not require costimulation for proliferation and differentiation into cytotoxic effector cells.

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12 December 2020

The roles of CD28 and CD40 ligand in T cell activation and tolerance

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12 December 2020

Role of antigen-presenting cells in mediating tolerance and autoimmunity

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12 December 2020

Immature dendritic cells acquire CD8(+) cytotoxic T lymphocyte priming capacity upon activation by T helper cell-independent or -dependent stimuli.

1 reference

12 December 2020

CD4(+)CD25(+) immune regulatory cells are required for induction of tolerance to alloantigen via costimulatory blockade

1 reference

12 December 2020

Requirements for the promotion of allogeneic engraftment by anti-CD154 (anti-CD40L) monoclonal antibody under nonmyeloablative conditions

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12 December 2020

Spontaneous murine B-cell leukaemia

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12 December 2020

Characterization of effector cells of graft vs leukemia following allogeneic bone marrow transplantation in mice inoculated with murine B-cell leukemia

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12 December 2020

CD28- T lymphocytes. Antigenic and functional properties.

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12 December 2020

Differential T cell costimulatory requirements in CD28-deficient mice

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12 December 2020

Spontaneous and IL-2-induced anti-leukemic and anti-host effects against tumor- and host-specific alloantigens

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12 December 2020

Tumor immunogenicity determines the effect of B7 costimulation on T cell-mediated tumor immunity

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12 December 2020

T cell costimulation by B7/BB1 induces CD8 T cell-dependent tumor rejection: an important role of B7/BB1 in the induction, recruitment, and effector function of antitumor T cells.

1 reference

12 December 2020

Interleukin-2 inhibits graft-versus-host disease-promoting activity of CD4+ cells while preserving CD4- and CD8-mediated graft-versus-leukemia effects.

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12 December 2020

In vivo blockade of CD28/CTLA4: B7/BB1 interaction with CTLA4-Ig reduces lethal murine graft-versus-host disease across the major histocompatibility complex barrier in mice

1 reference

12 December 2020

Effective graft-versus-leukemia effects independent of graft-versus-host disease after T cell-depleted allogeneic bone marrow transplantation in a murine model of B cell leukemia/lymphoma. Role of cell therapy and recombinant IL-2

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12 December 2020

Antibody to the ligand of CD40, gp39, blocks the occurrence of the acute and chronic forms of graft-vs-host disease

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12 December 2020

CTLA4Ig treatment ameliorates the lethality of murine graft-versus-host disease across major histocompatibility complex barriers

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12 December 2020

Preferential dependence of autoantibody production in murine lupus on CD86 costimulatory molecule

1 reference

12 December 2020

The role of antibodies to IL-2 receptor and Asialo GM1 on graft-versus-leukemia effects induced by bone marrow allografts in murine B cell leukemia.

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12 December 2020

B7-1 is superior to B7-2 costimulation in the induction and maintenance of T cell-mediated antileukemia immunity. Further evidence that B7-1 and B7-2 are functionally distinct

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12 December 2020

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

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12 December 2020

The differential role of CD86 and CD80 co-stimulatory molecules in the induction and the effector phases of contact hypersensitivity

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12 December 2020

Blockade of CD40 ligand-CD40 interaction impairs CD4+ T cell-mediated alloreactivity by inhibiting mature donor T cell expansion and function after bone marrow transplantation

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12 December 2020

Effect of CD80 and CD86 blockade and anti-interleukin-12 treatment on mouse acute graft-versus-host disease

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12 December 2020

The role of B7 costimulation by murine acute myeloid leukemia in the generation and function of a CD8+ T-cell line with potent in vivo graft-versus-leukemia properties.

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12 December 2020

CD40 ligand induces an antileukemia immune response in vivo.

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12 December 2020

CD28/B7 interactions are required for sustaining the graft-versus-leukemia effect of delayed post-bone marrow transplantation splenocyte infusion in murine recipients of myeloid or lymphoid leukemia cells

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12 December 2020

Blockade of CD40-CD40 ligand pathway induces tolerance in murine contact hypersensitivity

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12 December 2020

Gene transfer of CD40-ligand induces autologous immune recognition of chronic lymphocytic leukemia B cells

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12 December 2020

Purified MHC class I and peptide complexes activate naive CD8+ T cells independently of the CD28/B7 and LFA-1/ICAM-1 costimulatory interactions

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12 December 2020

Involvement of CD40 ligand-CD40 and CTLA4-B7 pathways in murine acute graft-versus-host disease induced by allogeneic T cells lacking CD28.

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12 December 2020

Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance

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12 December 2020

Antitumor effect of CD40 ligand: elicitation of local and systemic antitumor responses by IL-12 and B7.

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12 December 2020

Cutting edge: sustained expansion of CD8+ T cells requires CD154 expression by Th cells in acute graft versus host disease

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12 December 2020

A metalloproteinase inhibitor prevents acute graft-versus-host disease while preserving the graft-versus-leukaemia effect of allogeneic bone marrow transplantation

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12 December 2020

CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy

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12 December 2020

Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40

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12 December 2020

IL-11 separates graft-versus-leukemia effects from graft-versus-host disease after bone marrow transplantation.

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12 December 2020

Cutting edge: blockade of the CD28/B7 costimulatory pathway inhibits intestinal allograft rejection mediated by CD4+ but not CD8+ T cells

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12 December 2020

Blocking CD40 - CD154 and CD80/CD86 - CD28 interactions during primary allogeneic stimulation results in T cell anergy and high IL-10 production

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12 December 2020

Blockade of CTLA-4 signals inhibits Th2-mediated murine chronic graft-versus-host disease by an enhanced expansion of regulatory CD8+ T cells

1 reference

12 December 2020

10.1046/J.1365-2249.2002.01857.X

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12100023%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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