Differential regulation of p21waf-1/cip-1 and Mdm2 by etoposide: etoposide inhibits the p53-Mdm2 autoregulatory feedback loop (Q74451669)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10023685%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Differential regulation of p21waf-1/cip-1 and Mdm2 by etoposide: etoposide inhibits the p53-Mdm2 autoregulatory feedback loop (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10023685%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

E L Arriola

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10023685%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

A R Lopez

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10023685%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

C M Chresta

series ordinal

3

1 reference

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10 November 2019

language of work or name

English

0 references

publication date

1 January 1999

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10 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10023685%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

18

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10 November 2019

issue

4

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10 November 2019

page(s)

1081-1091

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Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential

10 November 2019

cites work

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The mdm2 proto-oncogene

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Mdm2 promotes the rapid degradation of p53

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p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase-directed drugs

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A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

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Two Distinct Mechanisms Regulate the Levels of a Cellular Tumor Antigen, p53

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