Thiopurine methyltransferase phenotype and genotype in relation to azathioprine therapy in autoimmune hepatitis (Q74752601)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12217596%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

title

Thiopurine methyltransferase phenotype and genotype in relation to azathioprine therapy in autoimmune hepatitis (English)

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12 November 2019

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Peter G Langley

1

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12 November 2019

James Underhill

2

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12 November 2019

J Michael Tredger

3

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12 November 2019

Suzanne Norris

4

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12 November 2019

Ian G McFarlane

5

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12 November 2019

publication date

1 October 2002

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12 November 2019

published in

Journal of Hepatology

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12 November 2019

volume

37

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12 November 2019

issue

4

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12 November 2019

page(s)

441-447

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Current and novel immunosuppressive therapy for autoimmune hepatitis

12 November 2019

cites work

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Human thiopurine methyltransferase pharmacogenetics. Kindred with a terminal exon splice junction mutation that results in loss of activity

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Genotypic and phenotypic analysis of the polymorphic thiopurine S-methyltransferase gene (TPMT) in a European population.

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Thiopurine methyltransferase genotype and the toxicity of azathioprine in Japanese

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Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia

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7 January 2021

Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance

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Clinical implications of thiopurine methyltransferase--optimization of drug dosage and potential drug interactions

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Thiopurine methyltransferase genotype predicts therapy-limiting severe toxicity from azathioprine

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Thiopurine methyltransferase alleles in British and Ghanaian populations

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The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations

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Rational dosing of azathioprine and 6-mercaptopurine

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Human erythrocyte thiopurine methyltransferase: radiochemical microassay and biochemical properties

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7 January 2021

Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy

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New developments in the immunosuppressive drug monitoring of cyclosporine, tacrolimus, and azathioprine

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Mutations that alter RNA splicing of the human HPRT gene: a review of the spectrum

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Azathioprine associated T-cell mutations in insulin-dependent diabetes mellitus

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Utilisation of erythrocyte 6-thioguanine metabolite levels to optimise azathioprine therapy in patients with inflammatory bowel disease

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7 January 2021

Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease

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7 January 2021

Randomised controlled trial of azathioprine withdrawal in autoimmune chronic active hepatitis

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7 January 2021

10.1016/S0168-8278(02)00214-3

Identifiers

DOI

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12 November 2019

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