Induction of heme oxygenase-1 (HO-1) and NAD[P]H: quinone oxidoreductase 1 (NQO1) by a phenolic antioxidant, butylated hydroxyanisole (BHA) and its metabolite, tert-butylhydroquinone (tBHQ) in primary-cultured human and rat hepatocytes (Q79264289)

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scientific article published on 18 October 2006

Language	Label	Description	Also known as
English	Induction of heme oxygenase-1 (HO-1) and NAD[P]H: quinone oxidoreductase 1 (NQO1) by a phenolic antioxidant, butylated hydroxyanisole (BHA) and its metabolite, tert-butylhydroquinone (tBHQ) in primary-cultured human and rat hepatocytes	scientific article published on 18 October 2006

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scholarly article

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20 December 2019

Induction of heme oxygenase-1 (HO-1) and NAD[P]H: quinone oxidoreductase 1 (NQO1) by a phenolic antioxidant, butylated hydroxyanisole (BHA) and its metabolite, tert-butylhydroquinone (tBHQ) in primary-cultured human and rat hepatocytes (English)

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20 December 2019

Celine Valeria Liew

3

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author name string

Young-Sam Keum

1

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20 December 2019

Yong-Hae Han

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20 December 2019

Changjiang Xu

5

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20 December 2019

Xiaoling Yuan

6

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20 December 2019

Michael P Shakarjian

7

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20 December 2019

Saeho Chong

8

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20 December 2019

Ah-Ng Kong

9

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publication date

18 October 2006

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Pharmaceutical Research

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23

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11

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20 December 2019

2586-2594

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20 December 2019

Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

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Safety assessment of butylated hydroxyanisole and butylated hydroxytoluene as antioxidant food additives

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heme activates the heme oxygenase-1 gene in renal epithelial cells by stabilizing Nrf2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygen radical formation during prostaglandin H synthase-mediated biotransformation of butylated hydroxyanisole.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heme oxygenase-1 in tissue pathology: the Yin and Yang

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

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The peroxidase-dependent activation of butylated hydroxyanisole and butylated hydroxytoluene (BHT) to reactive intermediates. Formation of BHT-quinone methide via a chemical-chemical interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

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Biliverdin reductase: a major physiologic cytoprotectant

1 reference

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12 December 2020

based on heuristic

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Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

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Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

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Cancer chemoprevention with dietary phytochemicals

1 reference

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12 December 2020

based on heuristic

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In vivo studies on butylated hydroxyanisole

1 reference

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12 December 2020

based on heuristic

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Effect of various levels of dietary butylated hydroxyanisole on methylazoxymethanol acetate-induced colon carcinogenesis in CF1 mice.

1 reference

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12 December 2020

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Molecular mechanisms of butylated hydroxylanisole-induced toxicity: induction of apoptosis through direct release of cytochrome c

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Products of heme oxygenase and their potential therapeutic applications

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of NAD(P)H:quinone oxidoreductase 1 to protection against carcinogenesis, and regulation of its gene by the Nrf2 basic-region leucine zipper and the arylhydrocarbon receptor basic helix-loop-helix transcription factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

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Disposition of single oral doses of butylated hydroxyanisole in man and rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

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Inhibition of Chemical Carcinogen-Induced Pulmonary Neoplasia by Butylated Hydroxyanisole

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention by isothiocyanates and their underlying molecular signaling mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

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Akt inactivation is a key event in indole-3-carbinol-induced apoptosis in PC-3 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of butylated hydroxyanisole on the tumorigenicity and metabolism of N-nitrosodimethylamine and N-nitrosopyrrolidine in A/J mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nrf2 as a novel molecular target for chemoprevention

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of reactive oxygen species due to metabolic activation of butylated hydroxyanisole

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

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Inhibition of the hepatocarcinogenicity of aflatoxin B1 in rats by low levels of the phenolic antioxidants butylated hydroxyanisole and butylated hydroxytoluene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

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Haem oxygenase-1 prevents cell death by regulating cellular iron.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Butylated hydroxyanisole in perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of deguelin on the phosphatidylinositol 3-kinase/Akt pathway and apoptosis in premalignant human bronchial epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

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Vasoactive properties of CORM-3, a novel water-soluble carbon monoxide-releasing molecule

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heme oxygenase-1: unleashing the protective properties of heme

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term culture of murine epidermal keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinone reductases multitasking in the metabolic world

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carbon monoxide produced by heme oxygenase-1 suppresses T cell proliferation via inhibition of IL-2 production

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effects of phenolic compounds on benzo(a)pyrene-induced neoplasia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary chemopreventive compounds and ARE/EpRE signaling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of (-)-epigallocatechin-3-gallate elicited liver and small intestine gene expression profiles between C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

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Nrf2: a potential molecular target for cancer chemoprevention by natural compounds

1 reference

https://pubmed.ncbi.nlm.nih.gov/17048120

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11095-006-9094-2

1 reference

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20 December 2019

1 reference

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20 December 2019

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