Structure and binding of Mg(II) ions and di-metal bridge complexes with biological phosphates and phosphoranes (Q80490535)

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1 January 2020

title

Structure and binding of Mg(II) ions and di-metal bridge complexes with biological phosphates and phosphoranes (English)

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3

Darrin M York

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author name string

Evelyn Mayaan

series ordinal

1

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Kevin Range

series ordinal

2

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publication date

20 August 2004

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Journal of Biological Inorganic Chemistry

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published in

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volume

9

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issue

7

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page(s)

807-817

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https://scigraph.springernature.com/pub.10.1007/s00775-004-0583-7

1 January 2020

exact match

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Ribonuclease P (RNase P) RNA is converted to a Cd(2+)-ribozyme by a single Rp-phosphorothioate modification in the precursor tRNA at the RNase P cleavage site

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Identification and characterization of a divalent metal ion-dependent cleavage site in the hammerhead ribozyme

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Solvent effects on the reaction coordinate of the hydrolysis of phosphates and sulfates: application of Hammond and anti-Hammond postulates to understand hydrolysis in solution

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The pentacovalent phosphorus intermediate of a phosphoryl transfer reaction

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The hammerhead ribozyme

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Evidence for a hydroxide ion bridging two magnesium ions at the active site of the hammerhead ribozyme

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Computer simulation of the chemical catalysis of DNA polymerases: discriminating between alternative nucleotide insertion mechanisms for T7 DNA polymerase

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Metal-phosphate interactions in the hammerhead ribozyme observed by 31P NMR and phosphorothioate substitutions

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A pH-dependent conformational change, rather than the chemical step, appears to be rate-limiting in the hammerhead ribozyme cleavage reaction

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12 December 2020

Theoretical evaluation of pK(a) in phosphoranes: implications for phosphate ester hydrolysis

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Biophysical and biochemical investigations of RNA catalysis in the hammerhead ribozyme

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Detection of a proton-transfer process by kinetic solvent isotope effects in NH(4)(+)-mediated reactions catalyzed by a hammerhead ribozyme

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Theoretical studies of enzymic reactions: dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme

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Diverse roles of metal ions in acyl-transferase ribozymes

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Outersphere and innersphere coordinated metal ions in an aminoacyl-tRNA synthetase ribozyme

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Multiple magnesium ions in the ribonuclease P reaction mechanism

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Explanation by the double-metal-ion mechanism of catalysis for the differential metal ion effects on the cleavage rates of 5'-oxy and 5'-thio substrates by a hammerhead ribozyme

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The Hydrolysis of RNA: From Theoretical Calculations to the Hammerhead Ribozyme-Mediated Cleavage of RNA

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12 December 2020

Molecular dynamics investigations of hammerhead ribozyme RNA

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12 December 2020

Observations on catalysis by hammerhead ribozymes are consistent with a two-divalent-metal-ion mechanism

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Defining the catalytic metal ion interactions in the Tetrahymena ribozyme reaction

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Does a single metal ion bridge the A-9 and scissile phosphate groups in the catalytically active hammerhead ribozyme structure?

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Theoretical examination of Mg(2+)-mediated hydrolysis of a phosphodiester linkage as proposed for the hammerhead ribozyme

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12 December 2020

10.1007/S00775-004-0583-7

Identifiers

DOI

1 reference

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