Genetic background effects of keratin 8 and 18 in a DDC-induced hepatotoxicity and Mallory-Denk body formation mouse model (Q83746814)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

title

Genetic background effects of keratin 8 and 18 in a DDC-induced hepatotoxicity and Mallory-Denk body formation mouse model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Heimo Müller

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

11

Kurt Zatloukal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

10

Michael Trauner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

8

Oleksiy Tsybrovskyy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

3

Andrea Thueringer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

2

Cornelia Stumptner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

12

Helmut Denk

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1

Johannes Haybaeck

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

author name string

Thomas Kolbe

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Thomas M Magin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Michael Hesse

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

publication date

26 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

published in

Laboratory Investigation

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

volume

92

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

page(s)

857-867

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22449798%20AND%20SRC:MED&resulttype=core&format=json

Intermediate filaments: from cell architecture to nanomechanics

27 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Structural and regulatory functions of keratins.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

A mutation of keratin 18 within the coil 1A consensus motif causes widespread keratin aggregation but cell type-restricted lethality in mice

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Cytoplasmic intermediate filaments revealed as dynamic and multipurpose scaffolds

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Mid-gestational lethality in mice lacking keratin 8

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Keratins regulate protein biosynthesis through localization of GLUT1 and -3 upstream of AMP kinase and Raptor

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Cytokeratins 8 and 19 in the mouse placental development

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Genome-wide analysis of hepatic fibrosis in inbred mice identifies the susceptibility locus Hfib1 on chromosome 15.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Keratins: guardians of the liver.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Keratins as susceptibility genes for end-stage liver disease

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Keratins let liver live: Mutations predispose to liver disease and crosslinking generates Mallory-Denk bodies.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Intermediate filament cytoskeleton of the liver in health and disease

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Hepatocyte cytokeratins are hyperphosphorylated at multiple sites in human alcoholic hepatitis and in a mallory body mouse model

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Keratin 8 and 18 hyperphosphorylation is a marker of progression of human liver disease

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

A disease- and phosphorylation-related nonmechanical function for keratin 8.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

"Heads and tails" of intermediate filament phosphorylation: multiple sites and functional insights.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Keratin mutation in transgenic mice predisposes to Fas but not TNF-induced apoptosis and massive liver injury.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Dual roles of intermediate filaments in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Mallory bodies revisited

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

From Mallory to Mallory-Denk bodies: what, how and why?

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

The genetic background modulates susceptibility to mouse liver Mallory-Denk body formation and liver injury.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

"IF-pathies": a broad spectrum of intermediate filament-associated diseases.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Mallory-Denk-bodies: lessons from keratin-containing hepatic inclusion bodies

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

In vitro production of Mallory bodies and intracellular hyaline bodies: the central role of sequestosome 1/p62.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Mallory body--a disease-associated type of sequestosome

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Bile acid-induced Mallory body formation in drug-primed mouse liver

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Disturbances in hepatic cell-cycle regulation in mice with assembly-deficient keratins 8/18

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Osteopontin: role in cell signaling and cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Osteopontin expression in normal and fibrotic liver. altered liver healing in osteopontin-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Nuclear factor inducing kinase: a key regulator in osteopontin- induced MAPK/IkappaB kinase dependent NF-kappaB-mediated promatrix metalloproteinase-9 activation

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Effects and regulation of osteopontin in rat hepatic stellate cells

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Intermediate filaments as signaling platforms

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Lessons from keratin 18 knockout mice: formation of novel keratin filaments, secondary loss of keratin 7 and accumulation of liver-specific keratin 8-positive aggregates

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Keratin 8 overexpression promotes mouse Mallory body formation

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Keratin 18 overexpression but not phosphorylation or filament organization blocks mouse Mallory body formation

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Cross β-sheet conformation of keratin 8 is a specific feature of Mallory-Denk bodies compared with other hepatocyte inclusions.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

p62 at the crossroads of autophagy, apoptosis, and cancer

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

p62 is involved in the mechanism of Mallory body formation.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Transglutaminase 2 regulates mallory body inclusion formation and injury-associated liver enlargement

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

To aggregate or not to aggregate? A new role for p62.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Keratin 8 mutations in patients with cryptogenic liver disease

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis.

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021

Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2012.49

7 January 2021