Localizations of Na(+)-D-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart (Q85748720)

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scientific article published on 11 October 2014

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English	Localizations of Na(+)-D-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart	scientific article published on 11 October 2014

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21 February 2020

Localizations of Na(+)-D-glucose cotransporters SGLT1 and SGLT2 in human kidney and of SGLT1 in human small intestine, liver, lung, and heart (English)

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21 February 2020

Thorsten Walles

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Thorsten Walles

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21 February 2020

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Ivana Vrhovac

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Daniela Balen Eror

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Dirk Klessen

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Christa Burger

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Davorka Breljak

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Ognjen Kraus

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Nikola Radović

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Stipe Jadrijević

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Ivan Aleksic

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Christoph Sauvant

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21 February 2020

Ivan Sabolić

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Hermann Koepsell

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11 October 2014

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1881-1898

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21 February 2020

https://scigraph.springernature.com/pub.10.1007/s00424-014-1619-7

0 references

SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

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Novel hypothesis to explain why SGLT2 inhibitors inhibit only 30-50% of filtered glucose load in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

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Apical sodium-sugar transport in pulmonary epithelium in situ

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

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Electron microscopic immunohistochemical localization of components of Na+-cotransporters along the rat nephron

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficacy and safety of empagliflozin for type 2 diabetes: a systematic review and meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for Na+-glucose cotransporter in type I alveolar epithelium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrahepatic bile ducts transport water in response to absorbed glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium/glucose cotransporter 1 (SGLT1)-mediated absorption of intestinal glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

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The human kidney low affinity Na+/glucose cotransporter SGLT2. Delineation of the major renal reabsorptive mechanism for D-glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SGLT2 mediates glucose reabsorption in the early proximal tubule.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RS1 (RSC1A1) regulates the exocytotic pathway of Na+-D-glucose cotransporter SGLT1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose-transporter-mediated positive inotropic effects in human myocardium of diabetic and nondiabetic patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization and histochemical localization of the rat intestinal Na(+)-D-glucose cotransporter by monoclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The high affinity Na+/glucose cotransporter. Re-evaluation of function and distribution of expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Maintenance and repair of the bronchiolar epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional distribution of SGLT activity in rat brain in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The SLC2 family of facilitated hexose and polyol transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutrient-dependent secretion of glucose-dependent insulinotropic polypeptide from primary murine K cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered pulmonary response to hyperoxia in Clara cell secretory protein deficient mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mucin is produced by clara cells in the proximal airways of antigen-challenged mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A glucose sensor hiding in a family of transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biology of human sodium glucose transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose depletion in the airway surface liquid is essential for sterility of the airways

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for electrogenic Na-glucose cotransport in tracheal epithelium.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of Na+-D-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LX4211, a dual SGLT1/SGLT2 inhibitor, improved glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Why Do SGLT2 inhibitors inhibit only 30-50% of renal glucose reabsorption in humans?

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clara cell: progenitor for the bronchiolar epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac aquaporins

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Na(+)-D-glucose cotransporter in muscle capillaries increases glucose permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

More than apical: Distribution of SGLT1 in Caco-2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative PCR tissue expression profiling of the human SGLT2 gene and related family members

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluid absorption by rat lung in situ: pathways for sodium entry in the luminal membrane of alveolar epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell-specific localization of glucose transporter proteins in mammalian lung.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathways for glucose transport in type II pneumocytes freshly isolated from adult guinea pig lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aquaporin-1 in cardiac endothelial cells is downregulated in ischemia, hypoxia and cardioplegia

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunohistochemical localization of Na+-dependent glucose transporter in rat jejunum

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of arterial-portal glucose gradients and phloridzin on bile glucose levels in perfused rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics, pharmacodynamics and safety of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, in subjects with renal impairment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic and molecular identification of sodium-dependent glucose transporter in normal rat cholangiocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rat renal glucose transporter SGLT1 exhibits zonal distribution and androgen-dependent gender differences

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KGA-2727, a novel selective inhibitor of a high-affinity sodium glucose cotransporter (SGLT1), exhibits antidiabetic efficacy in rodent models.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Empagliflozin: a new sodium-glucose co-transporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose reabsorption from bile. Evidence for a biliohepatic circulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clara cells and Clara cell 10 kD protein (CC10)

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Revised immunolocalization of the Na+-D-glucose cotransporter SGLT1 in rat organs with an improved antibody.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of the CHIP28 water channel in rat kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SGLT1 is a novel cardiac glucose transporter that is perturbed in disease states

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of the Na+-D-glucose cotransporter SGLT1 in the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the Na+-D-glucose cotransporter SGLT1 in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human cardiomyocytes express high level of Na+/glucose cotransporter 1 (SGLT1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose transporter gene expression in freshly isolated and cultured rat pneumocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression profiling of the solute carrier gene family in the mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose sensing in L cells: a primary cell study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25304002

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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