IL-15-dependent CD8+ CD122+ T cells ameliorate experimental autoimmune encephalomyelitis by modulating IL-17 production by CD4+ T cells (Q87628131)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25142300%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

IL-15-dependent CD8+ CD122+ T cells ameliorate experimental autoimmune encephalomyelitis by modulating IL-17 production by CD4+ T cells (English)

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experimental autoimmune encephalomyelitis

13 March 2020

main subject

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Ping Yu

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25142300%20AND%20SRC:MED&resulttype=core&format=json

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25142300%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Richard N Bamford

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25142300%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Thomas A Waldmann

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25142300%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

publication date

1 November 2014

1 reference

European Journal of Immunology

13 March 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25142300%20AND%20SRC:MED&resulttype=core&format=json

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25142300%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

volume

44

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25142300%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

page(s)

3330-3341

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25142300%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

issue

11

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Murine CD8+ T cells that specifically delete autologous CD4+ T cells expressing V beta 8 TCR: a role of the Qa-1 molecule

13 March 2020

cites work

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12 December 2020

Preclinical and phase I clinical trial of blockade of IL-15 using Mikbeta1 monoclonal antibody in T cell large granular lymphocyte leukemia

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The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design

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CD8+ T regulatory cells express the Ly49 Class I MHC receptor and are defective in autoimmune prone B6-Yaa mice

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Inhibition of TGF-β Signaling by IL-15: A New Role for IL-15 in the Loss of Immune Homeostasis in Celiac Disease

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Targeting the IL-15 receptor with an antagonist IL-15 mutant/Fc gamma2a protein blocks delayed-type hypersensitivity

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IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice

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12 December 2020

Cutting edge: CD8+CD122+ regulatory T cells produce IL-10 to suppress IFN-gamma production and proliferation of CD8+ T cells.

1 reference

12 December 2020

Phase 1 trial of IL-15 trans presentation blockade using humanized Mikβ1 mAb in patients with T-cell large granular lymphocytic leukemia

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Two discreet subsets of CD8 T cells modulate PLP(91-110) induced experimental autoimmune encephalomyelitis in HLA-DR3 transgenic mice

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12 December 2020

Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes

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A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis

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12 December 2020

T cells in multiple sclerosis and experimental autoimmune encephalomyelitis.

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12 December 2020

Increased numbers of interleukin-15-expressing cells in active ulcerative colitis

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12 December 2020

Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis

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12 December 2020

Simultaneous blockade of multiple immune system inhibitory checkpoints enhances antitumor activity mediated by interleukin-15 in a murine metastatic colon carcinoma model

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12 December 2020

Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes

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A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127

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Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model

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IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

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12 December 2020

Cutting edge: programmed death-1 defines CD8+CD122+ T cells as regulatory versus memory T cells.

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12 December 2020

Murine CXCR3+CD27bright NK cells resemble the human CD56bright NK-cell population

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12 December 2020

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

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12 December 2020

IL-15 mRNA expression is up-regulated in blood and cerebrospinal fluid mononuclear cells in multiple sclerosis (MS)

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12 December 2020

Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice

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12 December 2020

IL-15 is elevated in serum patients with type 1 diabetes mellitus

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12 December 2020

Functional subsets of mouse natural killer cells

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12 December 2020

CD8+CD28- T suppressor cells and the induction of antigen-specific, antigen-presenting cell-mediated suppression of Th reactivity

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12 December 2020

Characterization of the interleukin 2 receptor beta chain using three distinct monoclonal antibodies

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12 December 2020

Regulatory T cells and immune tolerance

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12 December 2020

Interleukin 15: biology and relevance to human disease

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12 December 2020

Insulin-dependent diabetes induced by pancreatic beta cell expression of IL-15 and IL-15Rα

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12 December 2020

The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells

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12 December 2020

A novel monoclonal antibody against murine IL-2 receptor beta-chain. Characterization of receptor expression in normal lymphoid cells and EL-4 cells

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12 December 2020

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

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12 December 2020

IL-15 is elevated in sera of patients with relapsing-remitting multiple sclerosis

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12 December 2020

Targeting interleukin-15 in patients with rheumatoid arthritis: a proof-of-concept study

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12 December 2020

Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-α production in rheumatoid arthritis

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12 December 2020

Essential role of CD8+CD122+ regulatory T cells in the recovery from experimental autoimmune encephalomyelitis

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12 December 2020

Essential roles of CD8+CD122+ regulatory T cells in the maintenance of T cell homeostasis

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12 December 2020

Multiple sclerosis: a coordinated immunological attack against myelin in the central nervous system

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12 December 2020

Increased levels of IL-15 mRNA in relapsing--remitting multiple sclerosis attacks

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12 December 2020

IL-15 exacerbates collagen-induced arthritis with an enhanced CD4+ T cell response to produce IL-17.

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12 December 2020

IL-15 is highly expressed in inflammatory bowel disease and regulates local T cell-dependent cytokine production

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12 December 2020

Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis.

1 reference

12 December 2020

Humanized Mik beta 1, a humanized antibody to the IL-2 receptor beta-chain that acts synergistically with humanized anti-TAC.

1 reference

12 December 2020

Regulatory functions of CD8+CD28– T cells in an autoimmune disease model

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12 December 2020

CD11b and CD27 reflect distinct population and functional specialization in human natural killer cells.

1 reference

12 December 2020

The multifaceted regulation of interleukin-15 expression and the role of this cytokine in NK cell differentiation and host response to intracellular pathogens

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12 December 2020

Reprogramming of CTLs into natural killer-like cells in celiac disease

1 reference

12 December 2020