The Rac1 splice form Rac1b favors mouse colonic mucosa regeneration and contributes to intestinal cancer progression (Q89472949)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29985482%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

title

The Rac1 splice form Rac1b favors mouse colonic mucosa regeneration and contributes to intestinal cancer progression (English)

1 reference

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5 April 2020

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5

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5 April 2020

author name string

Larissa Kotelevets

1

1 reference

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5 April 2020

Francine Walker

2

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5 April 2020

Godefroy Mamadou

3

1 reference

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5 April 2020

Thérèse Lehy

4

1 reference

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5 April 2020

Eric Chastre

6

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5 April 2020

publication date

9 July 2018

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5 April 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29985482%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

volume

37

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5 April 2020

issue

46

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5 April 2020

page(s)

6054-6068

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The consensus molecular subtypes of colorectal cancer

5 April 2020

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7 January 2021

Nanotechnologies for the treatment of colon cancer: From old drugs to new hope

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7 January 2021

Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors

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7 January 2021

Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways.

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7 January 2021

SPSB1-mediated HnRNP A1 ubiquitylation regulates alternative splicing and cell migration in EGF signaling.

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7 January 2021

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7 January 2021

Increased Rac1b expression sustains colorectal tumor cell survival

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7 January 2021

Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells

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7 January 2021

The 19-amino acid insertion in the tumor-associated splice isoform Rac1b confers specific binding to p120 catenin

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7 January 2021

Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition

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7 January 2021

Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson-Gilford progeria syndrome

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7 January 2021

B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival

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7 January 2021

RAC1b overexpression correlates with poor prognosis in KRAS/BRAF WT metastatic colorectal cancer patients treated with first-line FOLFOX/XELOX chemotherapy.

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7 January 2021

Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

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7 January 2021

RAC1b overexpression in papillary thyroid carcinoma: a role to unravel

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7 January 2021

R-Ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis

1 reference

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7 January 2021

Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling

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7 January 2021

Tumor cell expression of MMP3 as a prognostic factor for poor survival in pancreatic, pulmonary, and mammary carcinoma

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7 January 2021

Matrix metalloproteinase induction of Rac1b, a key effector of lung cancer progression

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7 January 2021

The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis

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7 January 2021

The Rac GTPase in Cancer: From Old Concepts to New Paradigms

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7 January 2021

Expression of Rac1b stimulates NF-kappaB-mediated cell survival and G1/S progression

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7 January 2021

Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation

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7 January 2021

Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

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7 January 2021

Ibuprofen inhibits colitis-induced overexpression of tumor-related Rac1b

1 reference

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7 January 2021

Rac1b enhances cell survival through activation of the JNK2/c-JUN/Cyclin-D1 and AKT2/MCL1 pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0389-7

7 January 2021

A Squalene-Based Nanomedicine for Oral Treatment of Colon Cancer.

1 reference

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7 January 2021

Spontaneous lesions in aging FVB/N mice

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7 January 2021

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

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7 January 2021

Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells

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7 January 2021

Visualization of a short-range Wnt gradient in the intestinal stem-cell niche.

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7 January 2021

A genetic study of the role of the Wnt/beta-catenin signalling in Paneth cell differentiation.

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7 January 2021

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

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7 January 2021

Interplay between metabolic identities in the intestinal crypt supports stem cell function

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7 January 2021

ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation

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7 January 2021

The ROS-generating oxidase Nox1 is required for epithelial restitution following colitis

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7 January 2021

Rac1b regulates NT3-stimulated Mek-Erk signaling, directing marrow-isolated adult multilineage inducible (MIAMI) cells toward an early neuronal phenotype

1 reference

https://api.crossref.org/works/10.1038%2FS41388-018-0389-7

7 January 2021

Insufficient ability of Rac1b to perturb cystogenesis

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7 January 2021

Rac1 GTPase-deficient HeLa cells present reduced DNA repair, proliferation, and survival under UV or gamma irradiation

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7 January 2021

Inactivation of JNK2 as carcinogenic factor in colitis-associated and sporadic colorectal carcinogenesis

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7 January 2021

p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium

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7 January 2021

Chronic endogenous hypergastrinemia in humans: evidence for a mitogenic effect on the colonic mucosa.

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PubMed

https://pubmed.ncbi.nlm.nih.gov/29985482

12 December 2020

inferred from PubMed ID database lookup

Rac1 mutations produce aberrant epithelial differentiation in the developing and adult mouse small intestine

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29985482

12 December 2020

inferred from PubMed ID database lookup

Rac1b recruits Dishevelled and β-catenin to Wnt target gene promoters independent of Wnt3A stimulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29985482

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41388-018-0389-7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29985482%20AND%20SRC:MED&resulttype=core&format=json

5 April 2020

1 reference