Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors (Q90539299)

PubMed ID

32198201

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32198201%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

title

Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors (English)

1 reference

PubMed ID

32198201

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32198201%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

main subject

Mouse hepatitis virus

0 references

molecular biology

of

Mouse hepatitis virus

1 reference

inferred from abstract

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32198201%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

Xufang Deng

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32198201%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

3

Susan C Baker

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32198201%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

publication date

20 March 2020

1 reference

PubMed ID

32198201

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32198201%20AND%20SRC:MED&resulttype=core&format=json

14 April 2020

number of pages

10

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32198201%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

volume

117

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32198201%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

page(s)

8094-8103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32198201%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

issue

14

1 reference

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Creative Commons Attribution 4.0 International

27 May 2020

copyright license

start time

20 March 2020

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Major genetic marker of nidoviruses encodes a replicative endoribonuclease

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The severe acute respiratory syndrome coronavirus Nsp15 protein is an endoribonuclease that prefers manganese as a cofactor

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New antiviral target revealed by the hexameric structure of mouse hepatitis virus nonstructural protein nsp15.

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Crystal structure and mechanistic determinants of SARS coronavirus nonstructural protein 15 define an endoribonuclease family

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Crystal Structure of a Monomeric Form of Severe Acute Respiratory Syndrome Coronavirus Endonuclease nsp15 Suggests a Role for Hexamerization as an Allosteric Switch

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Biochemical and genetic analyses of murine hepatitis virus Nsp15 endoribonuclease

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Structural and functional analyses of the severe acute respiratory syndrome coronavirus endoribonuclease Nsp15

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Murine Coronavirus Mouse Hepatitis Virus Is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/Microglia

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SARS-coronavirus replication is supported by a reticulovesicular network of modified endoplasmic reticulum

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The viral RNase E(rns) prevents IFN type-I triggering by pestiviral single- and double-stranded RNAs.

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Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity

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Biochemical characterization of arterivirus nonstructural protein 11 reveals the nidovirus-wide conservation of a replicative endoribonuclease

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Activation of MDA5 requires higher-order RNA structures generated during virus infection

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12 December 2020

Poly(A) at the 3' end of positive-strand RNA and VPg-linked poly(U) at the 5' end of negative-strand RNA are reciprocal templates during replication of poliovirus RNA.

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Murine coronavirus delays expression of a subset of interferon-stimulated genes

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Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3' to 5' exonuclease activity essential for immune suppression

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Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology

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Uridine composition of the poly-U/UC tract of HCV RNA defines non-self recognition by RIG-I.

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Pathogenic influenza viruses and coronaviruses utilize similar and contrasting approaches to control interferon-stimulated gene responses.

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Timing Is Everything: Coordinated Control of Host Shutoff by Influenza A Virus NS1 and PA-X Proteins

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The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication Sites

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Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice.

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Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation.

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Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses

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In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins.

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12 December 2020

Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication

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12 December 2020

Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages

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12 December 2020

An "Old" protein with a new story: Coronavirus endoribonuclease is important for evading host antiviral defenses.

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Combination and inducible adjuvants targeting nucleic acid sensors

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Coronavirus Endoribonuclease Activity in Porcine Epidemic Diarrhea Virus Suppresses Type I and Type III Interferon Responses

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Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection

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Identification and Characterization of a Human Coronavirus 229E Nonstructural Protein 8-Associated RNA 3'-Terminal Adenylyltransferase Activity

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1921485117

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32198201%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

27 May 2020

COVIDWHO ID

covidwho-11430

0 references

1125795813

1 reference

Dimensions COVID-19 publications, datasets and clinical trials

DOI

10.6084/M9.FIGSHARE.11961063

28 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32198201%20AND%20SRC:MED&resulttype=core&format=json

27 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32198201%20AND%20SRC:MED&resulttype=core&format=json