Long-read sequencing unveils IGH-DUX4 translocation into the silenced IGH allele in B-cell acute lymphoblastic leukemia (Q93052882)

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3 May 2020

title

Long-read sequencing unveils IGH-DUX4 translocation into the silenced IGH allele in B-cell acute lymphoblastic leukemia (English)

1 reference

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B-cell acute lymphoblastic leukemia

3 May 2020

main subject

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1

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3 May 2020

Beisi Xu

5

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3 May 2020

Scott Newman

10

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3 May 2020

Jinghui Zhang

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3 May 2020

author name string

Ying Shao

2

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3 May 2020

Stephanie Nance

3

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3 May 2020

Jinjun Dang

4

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3 May 2020

Xiaotu Ma

6

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3 May 2020

Yongjin Li

7

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3 May 2020

Bensheng Ju

8

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3 May 2020

Li Dong

9

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3 May 2020

Xin Zhou

11

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3 May 2020

Patrick Schreiner

12

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3 May 2020

Elizabeth Tseng

13

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3 May 2020

Ting Hon

14

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3 May 2020

Meredith Ashby

15

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3 May 2020

Chunliang Li

16

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3 May 2020

John Easton

17

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3 May 2020

Tanja A Gruber

18

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3 May 2020

publication date

26 June 2019

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3 May 2020

published in

Nature Communications

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3 May 2020

volume

10

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3 May 2020

issue

1

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3 May 2020

page(s)

2789

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Protein kinase A activation inhibits DUX4 gene expression in myotubes from patients with facioscapulohumeral muscular dystrophy

3 May 2020

cites work

1 reference

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Structural basis of DUX4/IGH-driven transactivation.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

Direct determination of diploid genome sequences

11 February 2021

1 reference

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AMKL chimeric transcription factors are potent inducers of leukemia

11 February 2021

1 reference

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Deregulation of DUX4 and ERG in acute lymphoblastic leukemia

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

Juicer Provides a One-Click System for Analyzing Loop-Resolution Hi-C Experiments

11 February 2021

1 reference

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Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

Sequential activation and distinct functions for distal and proximal modules within the IgH 3' regulatory region

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

Exploring genomic alteration in pediatric cancer using ProteinPaint

11 February 2021

1 reference

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Oncogene Overdose: Too Much of a Bad Thing for Oncogene-Addicted Cancer Cells

11 February 2021

1 reference

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HiC-Pro: an optimized and flexible pipeline for Hi-C data processing

11 February 2021

1 reference

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Multiplexed analysis of chromosome conformation at vastly improved sensitivity

11 February 2021

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Long-Range Regulation of V(D)J Recombination

11 February 2021

1 reference

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Replication stress and cancer

11 February 2021

1 reference

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Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

ATAC-seq: A Method for Assaying Chromatin Accessibility Genome-Wide

11 February 2021

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Epigenetic regulation of monoallelic rearrangement (allelic exclusion) of antigen receptor genes

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

The Hitchhiker's guide to Hi-C analysis: practical guidelines

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

HTSeq--a Python framework to work with high-throughput sequencing data

11 February 2021

1 reference

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Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

IGH@ translocations are prevalent in teenagers and young adults with acute lymphoblastic leukemia and are associated with a poor outcome.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

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11 February 2021

1 reference

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Understanding MYC-driven aggressive B-cell lymphomas: pathogenesis and classification

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

Role of the Igh intronic enhancer Eμ in clonal selection at the pre-B to immature B cell transition

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

Characterization of IGH locus breakpoints in multiple myeloma indicates a subset of translocations appear to occur in pregerminal center B cells.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

STAR: ultrafast universal RNA-seq aligner

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

DUX4 activates germline genes, retroelements, and immune mediators: implications for facioscapulohumeral dystrophy.

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

Enhancer-promoter communication and transcriptional regulation of Igh

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

Facioscapulohumeral muscular dystrophy and DUX4: breaking the silence

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

Integrative genomics viewer

11 February 2021

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Allelic exclusion of immunoglobulin genes: models and mechanisms

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

BSMAP: whole genome bisulfite sequence MAPping program

11 February 2021

1 reference

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11 February 2021

1 reference

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Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD).

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

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11 February 2021

1 reference

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11 February 2021

1 reference

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Cis-regulatory elements and epigenetic changes control genomic rearrangements of the IgH locus

11 February 2021

1 reference

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11 February 2021

1 reference

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11 February 2021

1 reference

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A stepwise epigenetic process controls immunoglobulin allelic exclusion

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

Hypomethylation of D4Z4 in 4q-linked and non-4q-linked facioscapulohumeral muscular dystrophy

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma

11 February 2021

1 reference

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BLAT—The BLAST-Like Alignment Tool

11 February 2021

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

11 February 2021

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6594946

10.1038/S41467-019-10637-8

11 February 2021

Identifiers

DOI

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3 May 2020

0 references

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3 May 2020

PubMed publication ID

31243274

1 reference