The Proteins of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2 or n-COV19), the Cause of COVID-19 (Q95649329)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32447571%20AND%20SRC:MED&resulttype=core&format=json

28 May 2020

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13 July 2022

22 October 2022

The Proteins of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2 or n-COV19), the Cause of COVID-19 (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32447571%20AND%20SRC:MED&resulttype=core&format=json

28 May 2020

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The Proteins of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2 or n-COV19), the Cause of COVID-19

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author

Francis K Yoshimoto

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32447571%20AND%20SRC:MED&resulttype=core&format=json

28 May 2020

publication date

23 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32447571%20AND%20SRC:MED&resulttype=core&format=json

28 May 2020

1 June 2020

2 references

13 July 2022

22 October 2022

3 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32447571%20AND%20SRC:MED&resulttype=core&format=json

28 May 2020

13 July 2022

22 October 2022

Potential of large "first generation" human-to-human transmission of 2019-nCoV

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Return of the Coronavirus: 2019-nCoV

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The establishment of reference sequence for SARS-CoV-2 and variation analysis

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Genomic characterization of a novel SARS-CoV-2

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The proximal origin of SARS-CoV-2

26 July 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Molecular Characteristics, Functions, and Related Pathogenicity of MERS-CoV Proteins

26 July 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

From SARS to MERS, Thrusting Coronaviruses into the Spotlight

26 July 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

From SARS to MERS: crystallographic studies on coronaviral proteases enable antiviral drug design

26 July 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Molecular Investigation of SARS-CoV-2 Proteins and Their Interactions with Antiviral Drugs

26 July 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Accessory proteins of SARS-CoV and other coronaviruses

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Drug targets for corona virus: A systematic review

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

A pneumonia outbreak associated with a new coronavirus of probable bat origin

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Computational inference of selection underlying the evolution of the novel coronavirus, SARS-CoV-2

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The EMBL-EBI search and sequence analysis tools APIs in 2019

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Severe acute respiratory syndrome coronavirus nonstructural protein 2 interacts with a host protein complex involved in mitochondrial biogenesis and intracellular signaling

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Two-amino acids change in the nsp4 of SARS coronavirus abolishes viral replication

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro): IMPLICATIONS FOR nsp5 REGULATION AND THE DEVELOPMENT OF ANTIVIRALS.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Coronavirus NSP6 restricts autophagosome expansion

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Severe acute respiratory syndrome coronavirus nonstructural proteins 3, 4, and 6 induce double-membrane vesicles

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The SARS-coronavirus nsp7+nsp8 complex is a unique multimeric RNA polymerase capable of both de novo initiation and primer extension

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Structure of the RNA-dependent RNA polymerase from COVID-19 virus

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The DEAD-box RNA helicase 5 positively regulates the replication of porcine reproductive and respiratory syndrome virus by interacting with viral Nsp9 in vitro

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Structural basis and functional analysis of the SARS coronavirus nsp14-nsp10 complex

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Coronavirus nsp10/nsp16 Methyltransferase Can Be Targeted by nsp10-Derived Peptide In Vitro and In Vivo To Reduce Replication and Pathogenesis

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

A high ATP concentration enhances the cooperative translocation of the SARS coronavirus helicase nsP13 in the unwinding of duplex RNA

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

In vitro reconstitution of SARS-coronavirus mRNA cap methylation

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Viral and Cellular mRNA Translation in Coronavirus-Infected Cells

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

RNA recognition and cleavage by the SARS coronavirus endoribonuclease

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Structural and functional analyses of the severe acute respiratory syndrome coronavirus endoribonuclease Nsp15

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The severe acute respiratory syndrome coronavirus Nsp15 protein is an endoribonuclease that prefers manganese as a cofactor

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

An "Old" protein with a new story: Coronavirus endoribonuclease is important for evading host antiviral defenses.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Coronavirus nonstructural protein 16 is a cap-0 binding enzyme possessing (nucleoside-2'O)-methyltransferase activity

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Crystal Structure and Functional Analysis of the SARS-Coronavirus RNA Cap 2′-O-Methyltransferase nsp10/nsp16 Complex

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Structural basis of receptor recognition by SARS-CoV-2

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Coronavirus envelope protein: current knowledge

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The missing link in coronavirus assembly. Retention of the avian coronavirus infectious bronchitis virus envelope protein in the pre-Golgi compartments and physical interaction between the envelope and membrane proteins

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The coronavirus E protein: assembly and beyond

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

A structural analysis of M protein in coronavirus assembly and morphology

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The SARS-coronavirus membrane protein induces apoptosis via interfering with PDK1-PKB/Akt signalling.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The nonstructural protein 8 (nsp8) of the SARS coronavirus interacts with its ORF6 accessory protein.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Severe acute respiratory syndrome coronavirus protein 6 is required for optimal replication

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The ORF7b protein of severe acute respiratory syndrome coronavirus (SARS-CoV) is expressed in virus-infected cells and incorporated into SARS-CoV particles

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Expression, post-translational modification and biochemical characterization of proteins encoded by subgenomic mRNA8 of the severe acute respiratory syndrome coronavirus

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Accessory proteins 8b and 8ab of severe acute respiratory syndrome coronavirus suppress the interferon signaling pathway by mediating ubiquitin-dependent rapid degradation of interferon regulatory factor 3.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The coronavirus nucleocapsid protein is ADP-ribosylated.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

SARS-CoV-2-encoded nucleocapsid protein acts as a viral suppressor of RNA interference in cells

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The nucleocapsid protein of severe acute respiratory syndrome-coronavirus inhibits the activity of cyclin-cyclin-dependent kinase complex and blocks S phase progression in mammalian cells

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Overlapping genes produce proteins with unusual sequence properties and offer insight into de novo protein creation

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Acquisition of new protein domains by coronaviruses: analysis of overlapping genes coding for proteins N and 9b in SARS coronavirus

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Genome Composition and Divergence of the Novel Coronavirus (2019-nCoV) Originating in China

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Non-canonical translation in RNA viruses

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Identification of novel subgenomic RNAs and noncanonical transcription initiation signals of severe acute respiratory syndrome coronavirus

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Identification of a severe acute respiratory syndrome coronavirus-like virus in a leaf-nosed bat in Nigeria

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

A new coronavirus associated with human respiratory disease in China

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The structure and functions of coronavirus genomic 3' and 5' ends

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Effect of Convalescent Plasma Therapy on Viral Shedding and Survival in COVID-19 Patients

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Update on treatment of COVID-19: ongoing studies between promising and disappointing results

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Race to find COVID-19 treatments accelerates

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Rethinking the role of hydroxychloroquine in the treatment of COVID-19

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Of chloroquine and COVID-19

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Hydroxychloroquine cardiotoxicity presenting as a rapidly evolving biventricular cardiomyopathy: key diagnostic features and literature review.

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) induce cell death via mitochondrial superoxide production and caspase activation in pancreatic cancer

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Traditional Chinese Medicine treatment of COVID-19

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Aristolochic acid-associated urothelial cancer in Taiwan

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Application of metabolomics in toxicity evaluation of traditional Chinese medicines

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Typical toxic components in traditional Chinese medicine

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

2019_nCoV/SARS-CoV-2: rapid classification of betacoronaviruses and identification of Traditional Chinese Medicine as potential origin of zoonotic coronaviruses

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Developing Covid-19 Vaccines at Pandemic Speed

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Treatment for emerging viruses: Convalescent plasma and COVID-19

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Beware of the second wave of COVID-19

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

First-wave COVID-19 transmissibility and severity in China outside Hubei after control measures, and second-wave scenario planning: a modelling impact assessment

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Genomic variance of the 2019-nCoV coronavirus

26 July 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245191

Treatment options for COVID-19: The reality and challenges

26 July 2020

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SARS-CoV-2: Recent Reports on Antiviral Therapies Based on Lopinavir/Ritonavir, Darunavir/Umifenovir, Hydroxychloroquine, Remdesivir, Favipiravir and Other Drugs for the Treatment of the New Coronavirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=7245191

A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals

10 February 2021

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Caution and clarity required in the use of chloroquine for COVID-19

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