TNF receptor superfamily member 1A (Q21110955)

http://www.ebi.ac.uk/interpro/protein/P19438

Death-like domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19438

Tumor necrosis factor receptor 1A, N-terminal domain, protein family

1 reference

Tumor necrosis factor receptor 1A, death domain, protein family

1 reference

Death domain, protein family

1 reference

TNFR/NGFR cysteine-rich region, protein family

1 reference

A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway

1 reference

13 November 2019

1 reference

13 November 2019

29 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Effect of antibodies to rat and human cerebral cortex and white matter on heterologous T- and B-cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

A novel role for the apoptosis inhibitor ARC in suppressing TNFα-induced regulated necrosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

SH3RF2 functions as an oncogene by mediating PAK4 protein stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

RAIDD is a new 'death' adaptor molecule

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Progranulin directly binds to the CRD2 and CRD3 of TNFR extracellular domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Proteinase-activated receptor-2 mediated inhibition of TNFalpha-stimulated JNK activation - A novel paradigm for G(q/11) linked GPCRs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Competitive control of independent programs of tumor necrosis factor receptor-induced cell death by TRADD and RIP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Riboflavin kinase couples TNF receptor 1 to NADPH oxidase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

The seventh zinc finger motif of A20 is required for the suppression of TNF-α-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Human tumor necrosis factor-alpha receptor. Purification by immunoaffinity chromatography and initial characterization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

tumor necrosis factor-activated receptor activity

IPI

3 references

21 June 2018

Molecular cloning and expression of a receptor for human tumor necrosis factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

tumor necrosis factor binding

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

identical protein binding

4 references

21 June 2018

TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

21 June 2018

A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

21 June 2018

Toward an understanding of the protein interaction network of the human liver

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

21 June 2018

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

tumor necrosis factor-activated receptor activity

IPI

4 references

8 April 2019

Molecular cloning and expression of a receptor for human tumor necrosis factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

integral component of membrane

cell component

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

1 reference

21 June 2018

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

2 references

integral component of plasma membrane

1 reference

8 April 2019

Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Identification of ARTS-1 as a novel TNFR1-binding protein that promotes TNFR1 ectodomain shedding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

1 reference

8 April 2019

Heterogeneity among patients with tumor necrosis factor receptor-associated periodic syndrome phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

tumor necrosis factor receptor superfamily complex

IDA

1 reference

8 April 2019

Tumor necrosis factor alpha: a link between neuroinflammation and excitotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

The shedding activity of ADAM17 is sequestered in lipid rafts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

regulation of apoptotic process

biological process

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

prostaglandin metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

positive regulation of ceramide biosynthetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

regulation of tumor necrosis factor-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

tumor necrosis factor-mediated signaling pathway

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Tumor necrosis factor alpha: a link between neuroinflammation and excitotoxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

response to lipopolysaccharide

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

cellular response to mechanical stimulus

1 reference

8 April 2019

Expression of the Bcl-2 protein BAD promotes prostate cancer growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

death-inducing signaling complex assembly

IEP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

regulation of cell population proliferation

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

defense response to bacterium

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19438&geneProductId=UniProtKB:P19438

intrinsic apoptotic signaling pathway in response to DNA damage

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

positive regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

8 April 2019

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

I-kappaB kinase/NF-kappaB signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

negative regulation of inflammatory response

1 reference

8 April 2019

Heterogeneity among patients with tumor necrosis factor receptor-associated periodic syndrome phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

regulation of establishment of endothelial barrier

1 reference

8 April 2019

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

extrinsic apoptotic signaling pathway via death domain receptors

1 reference

8 April 2019

TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

positive regulation of transcription by RNA polymerase II

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Signal pathways in astrocytes activated by cross-talk between of astrocytes and mast cells through CD40-CD40L

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

inflammatory response

cell surface receptor signaling pathway

ISS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

positive regulation of tyrosine phosphorylation of STAT protein

1 reference

8 April 2019

Signal pathways in astrocytes activated by cross-talk between of astrocytes and mast cells through CD40-CD40L

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

protein localization to plasma membrane

1 reference

8 April 2019

Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

cytokine-mediated signaling pathway

negative regulation of cardiac muscle hypertrophy

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

inflammatory response

4 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19438

D12.776.543.750.705.852.760.597

Identifiers

MeSH descriptor ID

D047888

subject named as

Receptors, Tumor Necrosis Factor, Type I

0 references

MeSH tree code

D12.776.543.750.690.750

0 references

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

0 references

Microsoft Academic ID

0 references

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016