Eph receptors and ephrin ligands: important players in angiogenesis and tumor angiogenesis (Q21328694)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224755%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

review article

1 reference

title

Eph receptors and ephrin ligands: important players in angiogenesis and tumor angiogenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224755%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

1 reference

3

Christin Neuber

Christin

Neuber

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224755%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

4

Jens Pietzsch

Jens

Pietzsch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224755%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Birgit Mosch

1

Birgit

Mosch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224755%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

Bettina Reissenweber

series ordinal

2

author given names

Bettina

author last names

Reissenweber

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224755%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

language of work or name

English

0 references

publication date

10 March 2010

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19 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224755%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

volume

2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224755%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

page(s)

135285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224755%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

19 January 2020

copyright license

start time

1 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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The role of Ephs, Ephrins, and growth factors in Kaposi sarcoma and implications of EphrinB2 blockade

12 September 2017

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12 September 2017

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Comparative 3'UTR analysis allows identification of regulatory clusters that drive Eph/ephrin expression in cancer cell lines

12 September 2017

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EphA2 overexpression promotes ovarian cancer growth

12 September 2017

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12 September 2017

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12 September 2017

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The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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Receptor tyrosine kinase EphB4 is a survival factor in breast cancer

12 September 2017

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Anti-EphA2 antibodies decrease EphA2 protein levels in murine CT26 colorectal and human MDA-231 breast tumors but do not inhibit tumor growth

12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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12 September 2017

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The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration.

12 September 2017

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Ephrin-B2 selectively marks arterial vessels and neovascularization sites in the adult, with expression in both endothelial and smooth-muscle cells

12 September 2017

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Eph receptors and ephrin ligands: embryogenesis to tumorigenesis

12 September 2017

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HuR binding to cytoplasmic mRNA is perturbed by heat shock

12 September 2017

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Bidirectional signals establish boundaries

12 September 2017

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Vascular channel formation by human melanoma cells in vivo and in vitro: vasculogenic mimicry

12 September 2017

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Tumor plasticity allows vasculogenic mimicry, a novel form of angiogenic switch. A rose by any other name?

12 September 2017

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Surface densities of ephrin-B1 determine EphB1-coupled activation of cell attachment through alphavbeta3 and alpha5beta1 integrins

12 September 2017

1 reference

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ELK and LERK-2 in developing kidney and microvascular endothelial assembly

12 September 2017

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Fighting cancer by attacking its blood supply

12 September 2017

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12 September 2017

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A potent inhibitor of endothelial cell proliferation is generated by proteolytic cleavage of the chemokine platelet factor 4.

21 January 2018

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Dasatinib synergizes with doxorubicin to block growth, migration, and invasion of breast cancer cells

12 September 2017

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Transcriptional switch of dormant tumors to fast-growing angiogenic phenotype

27 September 2017

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Downregulation of EphA1 in colorectal carcinomas correlates with invasion and metastasis

27 September 2017

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Aberrant methylation of EphA7 in human prostate cancer and its relation to clinicopathologic features

27 September 2017

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The EphA3 receptor is expressed in a subset of rhabdomyosarcoma cell lines and suppresses cell adhesion and migration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Signaling through ephrin-A ligand leads to activation of Src-family kinases, Akt phosphorylation, and inhibition of antigen receptor-induced apoptosis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

EphB4 provides survival advantage to squamous cell carcinoma of the head and neck

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

EphB4 controls blood vascular morphogenesis during postnatal angiogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Impaired tumor microenvironment in EphA2-deficient mice inhibits tumor angiogenesis and metastatic progression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Hypoxia up-regulates expression of Eph receptors and ephrins in mouse skin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Concurrent binding of anti-EphA3 antibody and ephrin-A5 amplifies EphA3 signaling and downstream responses: potential as EphA3-specific tumor-targeting reagents

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

EphB2 as a therapeutic antibody drug target for the treatment of colorectal cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Loss of EphB6 expression in metastatic melanoma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Regulation of vasculogenesis and angiogenesis by EphB/ephrin-B2 signaling between endothelial cells and surrounding mesenchymal cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Ephrin-A1 is expressed at sites of vascular development in the mouse

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Murine epidermal growth factor (EGF) fragment (33-42) inhibits both EGF- and laminin-dependent endothelial cell motility and angiogenesis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

VE-cadherin regulates EphA2 in aggressive melanoma cells through a novel signaling pathway: implications for vasculogenic mimicry

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Tyrosine phosphorylation of transmembrane ligands for Eph receptors

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Heparin-binding fragments of fibronectin are potent inhibitors of endothelial cell growth

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Overexpression confers an oncogenic potential upon the eph gene.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

The 16K Fragment of Prolactin Specifically Inhibits Basal or Fibroblast Growth Factor Stimulated Growth of Capillary Endothelial Cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Eph-ephrin promiscuity is now crystal clear

30 May 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Tissue transglutaminase clusters soluble A-type ephrins into functionally active high molecular weight oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Eph receptors and ephrins restrict cell intermingling and communication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Modulation of EphA receptor function by coexpressed ephrinA ligands on retinal ganglion cell axons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Over-expression of EphB3 enhances cell-cell contacts and suppresses tumor growth in HT-29 human colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Liver cancer: EphrinA2 promotes tumorigenicity through Rac1/Akt/NF-kappaB signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Eph B4 receptor signaling mediates endothelial cell migration and proliferation via the phosphatidylinositol 3-kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Ephrin B1 is expressed on human luteinizing granulosa cells in corpora lutea of the early luteal phase: the possible involvement of the B class Eph-ephrin system during corpus luteum formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Retinoic acid modulates the ability of macrophages to participate in the induction of the angiogenic phenotype in head and neck squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Role of receptor tyrosine kinase in the angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularization

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Expression of EphA2 and VEGF in squamous cell carcinoma of the tongue: correlation with the angiogenesis and clinical outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Soluble forms of EphrinB2 and EphB4 reduce retinal neovascularization in a model of proliferative retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Structure and thermodynamic characterization of the EphB4/Ephrin-B2 antagonist peptide complex reveals the determinants for receptor specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

An ephrin mimetic peptide that selectively targets the EphA2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

RNA interference targeting EphA2 inhibits proliferation, induces apoptosis, and cooperates with cytotoxic drugs in human glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Fibroblast growth factors are present in the extracellular matrix produced by endothelial cells invitro: Implications for a role of heparinase-like enzymes in the neovascular response

21 January 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F135285

Soluble form of ephrinB2 inhibits xenograft growth of squamous cell carcinoma of the head and neck.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Differential EphA2 epitope display on normal versus malignant cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Antibody targeting of the EphA2 tyrosine kinase inhibits malignant cell behavior

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation: role of epithelial cell kinase (Eck/EphA2).

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2836134

Immunotherapy of murine colon cancer using receptor tyrosine kinase EphA2-derived peptide-pulsed dendritic cell vaccines

29 November 2018

1 reference

12 December 2020

E-cadherin regulates the function of the EphA2 receptor tyrosine kinase

1 reference

12 December 2020

Hypoxia-inducible transcription factor-2alpha in endothelial cells regulates tumor neovascularization through activation of ephrin A1

1 reference

12 December 2020

Angiogenesis: a dynamic balance of stimulators and inhibitors

1 reference

12 December 2020

Identifiers

DOI

10.1155/2010/135285

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224755%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20224755%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

2 references