Molecular phenotyping of a UK population: defining the human serum metabolome (Q24289470)

David I Ellis

13

0 references

David I Broadhurst

David Broadhurst

3

0 references

Warwick Dunn

Warwick B Dunn

1

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Gordon C. Jayson

Gordon C Jayson

28

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Douglas Kell

Douglas B Kell

36

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Roy Goodacre

35

Royston Goodacre

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author name string

Wanchang Lin

2

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Marie Brown

5

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Eva Zelena

6

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Andrew A Vaughan

7

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Antony Halsall

8

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Nadine Harding

9

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Joshua D Knowles

10

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Sue Francis-McIntyre

11

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Andy Tseng

12

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Steve O'Hagan

14

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Gill Aarons

15

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Boben Benjamin

16

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Stephen Chew-Graham

17

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Carly Moseley

18

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Paula Potter

19

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Catherine L Winder

20

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Catherine Potts

21

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Paula Thornton

22

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Catriona McWhirter

23

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Mohammed Zubair

24

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Martin Pan

25

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Alistair Burns

26

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J Kennedy Cruickshank

27

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Nitin Purandare

29

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Frederick C W Wu

30

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Joe D Finn

31

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John N Haselden

32

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Andrew W Nicholls

33

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Ian D Wilson

Creative Commons Attribution 4.0 International

34

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language of work or name

English

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publication date

2015

1 reference

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11

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page(s)

9-26

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issue

1

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copyright license

start time

25 July 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1007/s11306-014-0707-1

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cites work

The human urine metabolome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Translational biomarker discovery in clinical metabolomics: an introductory tutorial

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

The human serum metabolome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Why most published research findings are false

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Metabolomics and systems pharmacology: why and how to model the human metabolic network for drug discovery

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

MetaboLights--an open-access general-purpose repository for metabolomics studies and associated meta-data

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Proposed minimum reporting standards for chemical analysis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Biochemistry and molecular cell biology of diabetic complications

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Human metabolic individuality in biomedical and pharmaceutical research

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Here is the evidence, now what is the hypothesis? The complementary roles of inductive and hypothesis-driven science in the post-genomic era

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Power failure: why small sample size undermines the reliability of neuroscience

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

A community-driven global reconstruction of human metabolism.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Metabolite profiles and the risk of developing diabetes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Interactome networks and human disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

A novel untargeted metabolomics correlation-based network analysis incorporating human metabolic reconstructions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

An analysis of a 'community-driven' reconstruction of the human metabolic network

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Metabolomic markers reveal novel pathways of ageing and early development in human populations

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

The prevalence of metabolic syndrome in children: a systematic review of the literature

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Redox proteomics: chemical principles, methodological approaches and biological/biomedical promises.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Genetic variation in metabolic phenotypes: study designs and applications

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Human serum metabolic profiles are age dependent

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Metabolite profiling identifies pathways associated with metabolic risk in humans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Human metabolic profiles are stably controlled by genetic and environmental variation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Metabolome-wide association study identifies multiple biomarkers that discriminate north and south Chinese populations at differing risks of cardiovascular disease: INTERMAP study

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Common and unique biological pathways associated with smoking initiation/progression, nicotine dependence, and smoking cessation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Plasma 25-hydroxyvitamin D concentration and metabolic syndrome among middle-aged and elderly Chinese individuals

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Human metabolic phenotype diversity and its association with diet and blood pressure.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Analysis of the adult human plasma metabolome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Obesity, metabolic syndrome, and type 2 diabetes: inflammatory basis of glucose metabolic disorders

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Systems biology, metabolic modelling and metabolomics in drug discovery and development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Metabolomics-based systems biology and personalized medicine: moving towards n = 1 clinical trials?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

GMD@CSB.DB: the Golm Metabolome Database

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Smoking accelerates biotin catabolism in women

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Gene selection and classification from microarray data using kernel machine

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Metabolomics and systems biology: making sense of the soup

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Fructosamine 3-kinase, an enzyme involved in protein deglycation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Elevated systolic blood pressure and risk of cardiovascular and renal disease: overview of evidence from observational epidemiologic studies and randomized controlled trials

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289517

Development and Performance of a Gas Chromatography−Time-of-Flight Mass Spectrometry Analysis for Large-Scale Nontargeted Metabolomic Studies of Human Serum

27 September 2017

1 reference

https://api.crossref.org/works/10.1007%2FS11306-014-0707-1

Identifying Important Risk Factors for Survival in Kidney Graft Failure Patients Using Random Survival Forests

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11306-014-0707-1

Statistical strategies for avoiding false discoveries in metabolomics and related experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11306-014-0707-1

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11306-014-0707-1

Proposed minimum reporting standards for data analysis in metabolomics

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1 reference

https://api.crossref.org/works/10.1007%2FS11306-014-0707-1

Comparison of effect sizes associated with biomarkers reported in highly cited individual articles and in subsequent meta-analyses

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1 reference

https://api.crossref.org/works/10.1007%2FS11306-014-0707-1

Theodor Bücher Lecture. Metabolomics, modelling and machine learning in systems biology - towards an understanding of the languages of cells. Delivered on 3 July 2005 at the 30th FEBS Congress and the 9th IUBMB conference in Budapest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11306-014-0707-1

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1 reference

https://api.crossref.org/works/10.1007%2FS11306-014-0707-1

Vitamin D, parathyroid hormone and the metabolic syndrome in middle-aged and older European men.

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1 reference

https://api.crossref.org/works/10.1007%2FS11306-014-0707-1

A pilot study of GC/MS-based serum metabolic profiling of acute rejection in renal transplantation

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1 reference

https://api.crossref.org/works/10.1007%2FS11306-014-0707-1

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1 reference

https://api.crossref.org/works/10.1007%2FS11306-014-0707-1

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1 reference

https://api.crossref.org/works/10.1007%2FS11306-014-0707-1

An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse

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1 reference

https://api.crossref.org/works/10.1007%2FS11306-014-0707-1

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1 reference

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1 reference

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1 reference

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1 reference

12 December 2020

10.1007/S11306-014-0707-1

Identifiers

DOI

1 reference

Dimensions Publication ID

587649

1024965129

0 references

587649

1 reference

1 reference

1 reference