The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family (Q24292365)

P21 (RAC1) activated kinase 1

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Rho guanine nucleotide exchange factor 7

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Protein phosphatase, Mg2+/Mn2+ dependent 1F

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positive regulation of stress fiber assembly

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author name string

Cheng-Gee Koh

1

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E-Jean Tan

2

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Edward Manser

3

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Louis Lim

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

4

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language of work or name

English

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publication date

19 February 2002

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published in

Current Biology

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volume

12

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issue

4

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page(s)

317-21

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7 January 2021

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

Protein phosphatase 2Calpha inhibits the human stress-responsive p38 and JNK MAPK pathways

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

Ptc1, a type 2C Ser/Thr phosphatase, inactivates the HOG pathway by dephosphorylating the mitogen-activated protein kinase Hog1

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

A novel protein phosphatase that dephosphorylates and regulates Ca2+/calmodulin-dependent protein kinase II.

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

Substrate specificity of Ca(2+)/calmodulin-dependent protein kinase phosphatase: kinetic studies using synthetic phosphopeptides as model substrates

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

Regulation of postsynaptic structure and protein localization by the Rho-type guanine nucleotide exchange factor dPix

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

Coupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassembly

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

Neutrophils stimulated with a variety of chemoattractants exhibit rapid activation of p21-activated kinases (Paks): separate signals are required for activation and inactivation of paks

1 reference

https://api.crossref.org/works/10.1016%2FS0960-9822%2802%2900652-8

7 January 2021

10.1016/S0960-9822(02)00652-8

Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

2049270

2049270

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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