Apolipoprotein(a) acts as a chemorepellent to human vascular smooth muscle cells via integrin αVβ3 and RhoA/ROCK-mediated mechanisms (Q24294266)

integrin subunit alpha V

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Integrin subunit beta 3

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Apolipoprotein A1

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negative chemotaxis

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4

Michelle Peckham

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Kirsten Riches

Kirsten Riches

1

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Neil A. Turner

Neil A Turner

12

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Karen E Porter

13

Karen E Porter

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Azhar Maqbool

3

Azhar Maqbool

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Philip Warburton

7

Philip Warburton

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author name string

Larissa Franklin

2

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Matthew Adams

5

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Jacquelyn Bond

6

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Nicole T Feric

8

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Marlys L Koschinsky

9

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David J O'Regan

10

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Stephen G Ball

International Journal of Biochemistry & Cell Biology

11

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language of work or name

English

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publication date

August 2013

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published in

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volume

45

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issue

8

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page(s)

1776-83

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copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731554

describes a project that uses

ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3731554/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Neuronal chemorepellent Slit2 inhibits vascular smooth muscle cell migration by suppressing small GTPase Rac1 activation

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Lipoprotein(a) in atherosclerotic plaques recruits inflammatory cells through interaction with Mac-1 integrin

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Expression profiling identifies smooth muscle cell diversity within human intima and plaque fibrous cap: loss of RGS5 distinguishes the cap

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Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia

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Molecular regulation of vascular smooth muscle cell differentiation in development and disease

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Lipoprotein(a): Cellular Effects and Molecular Mechanisms

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Absence of Akt1 reduces vascular smooth muscle cell migration and survival and induces features of plaque vulnerability and cardiac dysfunction during atherosclerosis.

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Apolipoprotein(a), through its strong lysine-binding site in KIV(10'), mediates increased endothelial cell contraction and permeability via a Rho/Rho kinase/MYPT1-dependent pathway

27 September 2017

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27 September 2017

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Lipoprotein (a) inhibits the generation of transforming growth factor beta: an endogenous inhibitor of smooth muscle cell migration

27 September 2017

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Effects of wild-type (Trp72) and mutant (Arg72) apolipoprotein(a) kringle IV-10 on the proliferation of human arterial smooth muscle cells

30 May 2018

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Impact of HMG CoA reductase inhibition on small GTPases in the heart

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Apolipoprotein(a): expression and characterization of a recombinant form of the protein in mammalian cells

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Lipoprotein(a) as a potential causal genetic risk factor of cardiovascular disease: a rationale for increased efforts to understand its pathophysiology and develop targeted therapies

30 May 2018

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Lipoprotein (a) and carotid atherosclerosis in young patients with stroke

29 November 2018

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Apoptosis, cell proliferation and modulation of cyclin-dependent kinase inhibitor p21(cip1) in vascular remodelling during vein arterialization in the rat.

29 November 2018

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Effects of atorvastatin on Lp(a) and lipoprotein profiles in hemodialysis patients

29 November 2018

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Expansive remodeling in venous bypass grafts: novel implications for vein graft disease.

29 November 2018

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Selective gene silencing of either MMP-2 or MMP-9 inhibits invasion of human saphenous vein smooth muscle cells.

29 November 2018

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The effect of six different statins on the proliferation, migration, and invasion of human smooth muscle cells

29 November 2018

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Percutaneous coronary intervention results in acute increases in oxidized phospholipids and lipoprotein(a): short-term and long-term immunologic responses to oxidized low-density lipoprotein

29 November 2018

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The apolipoprotein(a) component of lipoprotein(a) stimulates actin stress fiber formation and loss of cell-cell contact in cultured endothelial cells

29 November 2018

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Report of the National Heart, Lung, and Blood Institute Workshop on Lipoprotein(a) and Cardiovascular Disease: recent advances and future directions

29 November 2018

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Association of lipoprotein(a) excess with early vein graft occlusions in middle-aged men undergoing coronary artery bypass surgery

29 November 2018

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Temporal increases in plasma markers of oxidized low-density lipoprotein strongly reflect the presence of acute coronary syndromes

29 November 2018

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Mitogenic activity of oxidized lipoprotein (a) on human vascular smooth muscle cells

29 November 2018

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Simvastatin inhibits human saphenous vein neointima formation via inhibition of smooth muscle cell proliferation and migration

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731554

Sphingosine-1-phosphate, a platelet-derived lysophospholipid mediator, negatively regulates cellular Rac activity and cell migration in vascular smooth muscle cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731554

Oxidative stress and lipid retention in vascular grafts: comparison between venous and arterial conduits

29 November 2018

1 reference

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The immediate effect of streptokinase on serum lipoprotein(a) concentration and the effect of myocardial infarction on serum lipoprotein(a), apolipoproteins A1 and B, lipids and C-reactive protein.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731554

Serum Lp(a) level as a predictor of vein graft stenosis after coronary artery bypass surgery in patients

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731554

Differential Gene Expression in Vascular Smooth Muscle Cells in Primary Atherosclerosis and In Stent Stenosis in Humans

29 November 2018

1 reference

12 December 2020

External stenting reduces long-term medial and neointimal thickening and platelet derived growth factor expression in a pig model of arteriovenous bypass grafting

1 reference

12 December 2020

CC chemokine I-309 is the principal monocyte chemoattractant induced by apolipoprotein(a) in human vascular endothelial cells

1 reference

12 December 2020

Stimulation of vascular smooth muscle cell proliferation and migration by apolipoprotein(a) is dependent on inhibition of transforming growth factor-beta activation and on the presence of kringle IV type 9

1 reference

12 December 2020

Lipoprotein(a) in homozygous familial hypercholesterolemia

1 reference

12 December 2020

Effects of one year of treatment with pravastatin, an HMG-CoA reductase inhibitor, on lipoprotein a

1 reference

12 December 2020

Inhibition of rho-associated kinase results in suppression of neointimal formation of balloon-injured arteries

1 reference

12 December 2020

Quantitation and localization of apolipoproteins [a] and B in coronary artery bypass vein grafts resected at re-operation

1 reference

12 December 2020

HMG CoA reductase inhibitors lower LDL cholesterol without reducing Lp(a) levels

1 reference

12 December 2020

Apolipoprotein(a) stimulates vascular endothelial cell growth and migration and signals through integrin alphaVbeta3

1 reference

12 December 2020

Lipoprotein(a) is a potent chemoattractant for human peripheral monocytes

1 reference

12 December 2020