Cell cycle control of wnt receptor activation (Q24294429)

Cyclin Y

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Cyclin dependent kinase 14

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regulation of canonical Wnt signaling pathway

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Cyclin Y Dmel_CG14939

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author name string

Gary Davidson

1

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Jinlong Shen

2

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Ya-Lin Huang

3

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Yi Su

4

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Emil Karaulanov

5

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Kerstin Bartscherer

6

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Christine Hassler

7

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Peter Stannek

8

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Michael Boutros

9

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Christof Niehrs

Antagonizing the Spemann organizer: role of the homeobox gene Xvent-1.

10

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language of work or name

English

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publication date

December 2009

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published in

Developmental Cell

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volume

17

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page(s)

788-99

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issue

6

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cites work

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Beta-catenin signaling activity dissected in the early Xenopus embryo: a novel antisense approach

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The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos

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Genetic control of cell division patterns in the Drosophila embryo

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cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2.

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The role of the Ser/Thr cluster in the phosphorylation of PPPSP motifs in Wnt coreceptors

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Wnt/beta-catenin signaling in cancer stemness and malignant behavior

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Secretion of Wnt ligands requires Evi, a conserved transmembrane protein

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Wnt/beta-catenin signaling in development and disease

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Transcription under the control of nuclear Arm/beta-catenin.

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Mechanisms underlying differential responses to FGF signaling

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Apc tumor suppressor gene is the "zonation-keeper" of mouse liver

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Multiple PPPS/TP motifs act in a combinatorial fashion to transduce Wnt signaling through LRP6.

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Cyclin Y, a novel membrane-associated cyclin, interacts with PFTK1

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Wnt-dependent spindle polarization in the early C. elegans embryo

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Ciliary margin transdifferentiation from neural retina is controlled by canonical Wnt signaling.

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Studying nuclear disassembly in vitro using Xenopus egg extract.

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OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways

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Recycling the Cell Cycle

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Mitotic repression of the transcriptional machinery.

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A mechanism for Wnt coreceptor activation

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

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arrow encodes an LDL-receptor-related protein essential for Wingless signalling

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An LDL-receptor-related protein mediates Wnt signalling in mice

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Forkhead transcription factors contribute to execution of the mitotic programme in mammals

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Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

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A new member of the frizzled family from Drosophila functions as a Wingless receptor

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Genome-wide survey of protein kinases required for cell cycle progression.

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Wnt signalling in stem cells and cancer

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Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction

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A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

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System-level identification of transcriptional circuits underlying mammalian circadian clocks

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Regionally specific induction by the Spemann-Mangold organizer

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WNT and beta-catenin signalling: diseases and therapies

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A novel role of phospho-beta-catenin in microtubule regrowth at centrosome

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Retrograde signalling at the synapse: a role for Wnt proteins

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Cytoskeletal reorganization by soluble Wnt-3a protein signalling

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Aberrant Wnt/beta-catenin signaling can induce chromosomal instability in colon cancer

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Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo.

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R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6

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Functional characterization of human PFTK1 as a cyclin-dependent kinase

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LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin

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Response of small intestinal epithelial cells to acute disruption of cell division through CDC25 deletion

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Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt-1 transgenic mice by insertional activation of int-2/Fgf-3 and hst/Fgf-4.

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Identification of a role for beta-catenin in the establishment of a bipolar mitotic spindle

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Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6.

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Analysis of the signaling activities of localization mutants of beta-catenin during axis specification in Xenopus

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Exogenous expression of beta-catenin regulates contact inhibition, anchorage-independent growth, anoikis, and radiation-induced cell cycle arrest

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Novel members of the cdc2-related kinase family in Drosophila: cdk4/6, cdk5, PFTAIRE, and PITSLRE kinase

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Beta-catenin regulation during the cell cycle: implications in G2/M and apoptosis

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The Spemann organizer and embryonic head induction

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E-RNAi: a web application to design optimized RNAi constructs

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beta-Catenin is a Nek2 substrate involved in centrosome separation

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The protein kinase complement of the human genome

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7 January 2021

Genome-wide RNAi analysis of growth and viability in Drosophila cells

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Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation

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7 January 2021

Identification of c-MYC as a target of the APC pathway

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7 January 2021

Analysis of endogenous LRP6 function reveals a novel feedback mechanism by which Wnt negatively regulates its receptor

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7 January 2021

Cyclin-dependent kinases: engines, clocks, and microprocessors

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7 January 2021

Mechanisms of Wnt signaling in development

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7 January 2021

The Wnt signaling pathway in development and disease

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A Drosophila protein-interaction map centered on cell-cycle regulators

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7 January 2021

Kremen is required for neural crest induction in Xenopus and promotes LRP6-mediated Wnt signaling.

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7 January 2021

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Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

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7 January 2021

FoxM1-driven cell division is required for neuronal differentiation in early Xenopus embryos.

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7 January 2021

Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development

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7 January 2021

Adenomatous polyposis coli (APC): a multi-functional tumor suppressor gene

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Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling

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7 January 2021

Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6.

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Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections

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Glycogen synthase kinase-3--an overview of an over-achieving protein kinase

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Cross-talk of WNT and FGF signaling pathways at GSK3beta to regulate beta-catenin and SNAIL signaling cascades

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7 January 2021