Phosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinase (Q24296672)

X-ray repair cross complementing 4

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DNA ligase 4

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Ligase IV, DNA, ATP-dependent

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Protein kinase, DNA activated, catalytic polypeptide

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X-ray repair complementing defective repair in Chinese hamster cells 4

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author

Mauro Modesti

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author name string

Yu-Gang Wang

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Chinonye Nnakwe

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William S Lane

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Karen M Frank

Journal of Biological Chemistry

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language of work or name

English

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publication date

3 September 2004

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published in

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volume

279

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page(s)

37282-90

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issue

36

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cites work

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The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation

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Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions

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The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit

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7 January 2021