Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling (Q24297849)

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26 December 2019

title

Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling (English)

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8

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Daniel Krappmann

10

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26 December 2019

Jorg Tatzelt

11

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26 December 2019

Konstanze Winklhofer

12

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9

Benedikt Berninger

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26 December 2019

author name string

Iris H Henn

1

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26 December 2019

Lena Bouman

2

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26 December 2019

Julia S Schlehe

3

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Anita Schlierf

4

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Julia E Schramm

5

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26 December 2019

Elmar Wegener

6

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26 December 2019

Kazuhiro Nakaso

7

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language of work or name

English

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publication date

1 February 2007

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26 December 2019

published in

Journal of Neuroscience

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26 December 2019

volume

27

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26 December 2019

issue

8

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26 December 2019

page(s)

1868-1878

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

26 December 2019

cites work

1 reference

12 December 2020

Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients

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12 December 2020

Roles of nuclear factor kappaB in neuronal survival and plasticity

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12 December 2020

The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component.

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12 December 2020

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

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12 December 2020

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

1 reference

12 December 2020

B-cell receptor- and phorbol ester-induced NF-kappaB and c-Jun N-terminal kinase activation in B cells requires novel protein kinase C's

1 reference

12 December 2020

Geldanamycin restores a defective heat shock response in vivo

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12 December 2020

NF-kappaB at the crossroads of life and death

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12 December 2020

Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies

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12 December 2020

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

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12 December 2020

Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death.

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12 December 2020

Tetrameric oligomerization of IkappaB kinase gamma (IKKgamma) is obligatory for IKK complex activity and NF-kappaB activation

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12 December 2020

Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity

1 reference

12 December 2020

Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila

1 reference

12 December 2020

New parkin mutations and atypical phenotypes in families with autosomal recessive parkinsonism

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12 December 2020

Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age.

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12 December 2020

Inactivation of parkin by oxidative stress and C-terminal truncations: a protective role of molecular chaperones

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12 December 2020

Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival

1 reference

12 December 2020

Genetics of parkin-linked disease.

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12 December 2020

Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity

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12 December 2020

Parkin genetics: one model for Parkinson's disease

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12 December 2020

Parkin counteracts symptoms in a Drosophila model of Parkinson's disease

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12 December 2020

Parkin attenuates manganese-induced dopaminergic cell death

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12 December 2020

Parkin protects human dopaminergic neuroblastoma cells against dopamine-induced apoptosis

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12 December 2020

Signaling to NF-kappaB

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12 December 2020

NF-kappaB signaling: flipping the switch with polyubiquitin chains

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12 December 2020

Polyubiquitin chains: polymeric protein signals

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12 December 2020

Parkin phosphorylation and modulation of its E3 ubiquitin ligase activity

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12 December 2020

Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease

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12 December 2020

Pathogenic mutations inactivate parkin by distinct mechanisms.

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12 December 2020

Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains

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12 December 2020

A pervasive role of ubiquitin conjugation in activation and termination of IkappaB kinase pathways

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12 December 2020

Signaling via NF-kappaB in the nervous system

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12 December 2020

Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin.

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12 December 2020

Ubiquitin signalling in the NF-kappaB pathway

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12 December 2020

Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A

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12 December 2020

Ubiquitylation and cell signaling

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12 December 2020

Dopamine covalently modifies and functionally inactivates parkin

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12 December 2020

Impaired transcriptional upregulation of Parkin promoter variant under oxidative stress and proteasomal inhibition: clinical association

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12 December 2020

Stress-induced alterations in parkin solubility promote parkin aggregation and compromise parkin's protective function

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12 December 2020

Diverse effects of pathogenic mutations of Parkin that catalyze multiple monoubiquitylation in vitro

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12 December 2020

Detection of compound heterozygous deletions in the parkin gene of fibroblasts in patients with autosomal recessive hereditary parkinsonism (PARK2).

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12 December 2020

Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells

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12 December 2020

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

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12 December 2020

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein.

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12 December 2020

Different mechanisms control signal-induced degradation and basal turnover of the NF-kappaB inhibitor IkappaB alpha in vivo

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12 December 2020

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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12 December 2020

10.1523/JNEUROSCI.5537-06.2007

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

4370910

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17314283%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

4370910

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Consolidated OpenCitations Corpus – April 2017

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26 December 2019

PubMed publication ID

17314283

2 references

Consolidated OpenCitations Corpus – April 2017

4370910