The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA (Q24307375)

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25 January 2020

title

The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA (English)

1 reference

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25 January 2020

main subject

Casein kinase 2 alpha 1

1 reference

Small ubiquitin like modifier 1

1 reference

PML nuclear body scaffold

1 reference

Small ubiquitin like modifier 2

1 reference

Protein inhibitor of activated STAT 2

1 reference

protein phosphorylation

1 reference

Protein inhibitor of activated STAT 1

1 reference

author

Georgia Konstantinidou

3

1 reference

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25 January 2020

Alessandro Rimessi

5

1 reference

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25 January 2020

Pier Paolo Scaglioni

11

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25 January 2020

7

John V Heymach

1 reference

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25 January 2020

author name string

Andrea Rabellino

1

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25 January 2020

Brandon Carter

2

1 reference

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25 January 2020

Shwu-Yuan Wu

4

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25 January 2020

Lauren A Byers

6

1 reference

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25 January 2020

Luc Girard

8

1 reference

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25 January 2020

Cheng-Ming Chiang

9

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25 January 2020

Julie Teruya-Feldstein

10

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25 January 2020

language of work or name

English

0 references

publication date

9 March 2012

1 reference

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25 January 2020

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25 January 2020

volume

72

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25 January 2020

issue

9

1 reference

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25 January 2020

page(s)

2275-2284

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Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

25 January 2020

cites work

1 reference

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Crosstalk between sumoylation and acetylation regulates p53-dependent chromatin transcription and DNA binding

19 March 2017

1 reference

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RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

19 March 2017

1 reference

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The mechanisms of PML-nuclear body formation

19 March 2017

1 reference

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A CK2-dependent mechanism for degradation of the PML tumor suppressor

19 March 2017

1 reference

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Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity

19 March 2017

1 reference

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PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

19 March 2017

1 reference

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Concepts in sumoylation: a decade on

19 March 2017

1 reference

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Regulation of gene-activation pathways by PIAS proteins in the immune system

19 March 2017

1 reference

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PML protein isoforms and the RBCC/TRIM motif

19 March 2017

1 reference

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Involvement of PIAS1 in the sumoylation of tumor suppressor p53

19 March 2017

1 reference

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Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor alpha degradation

19 March 2017

1 reference

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Identification of three major sentrinization sites in PML

19 March 2017

1 reference

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Role of PML in cell growth and the retinoic acid pathway

19 March 2017

1 reference

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Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

19 March 2017

1 reference

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A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

7 April 2017

1 reference

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SUMOylation-regulated protein phosphorylation, evidence from quantitative phosphoproteomics analyses

7 April 2017

1 reference

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A novel proteomics approach to identify SUMOylated proteins and their modification sites in human cells

27 September 2017

1 reference

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Acute promyelocytic leukaemia: novel insights into the mechanisms of cure

27 September 2017

1 reference

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The ligase PIAS1 restricts natural regulatory T cell differentiation by epigenetic repression

27 September 2017

1 reference

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Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML.

27 September 2017

1 reference

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Enhanced identification and biological validation of differential gene expression via Illumina whole-genome expression arrays through the use of the model-based background correction methodology

27 September 2017

1 reference

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Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway

27 September 2017

1 reference

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The theory of APL revisited

27 September 2017

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Identification of a tumour suppressor network opposing nuclear Akt function

27 September 2017

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In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia.

27 September 2017

1 reference

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A sumoylation site in PML/RARA is essential for leukemic transformation.

27 September 2017

1 reference

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Loss of the tumor suppressor PML in human cancers of multiple histologic origins

27 September 2017

1 reference

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Maturation sensitive and resistant t(15;17) NB4 cell lines as tools for APL physiopathology: nomenclature of cells and repertory of their known genetic alterations and phenotypes

27 September 2017

1 reference

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PML/RARA oxidation and arsenic binding initiate the antileukemia response of As2O3.

27 September 2017

1 reference

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Phospho-regulated SUMO interaction modules connect the SUMO system to CK2 signaling

29 November 2018

1 reference

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The PML growth-suppressor has an altered expression in human oncogenesis

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22406621

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-11-3159

2 references

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25 January 2020

1 reference

2 references

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25 January 2020

2 references