DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1 (Q24307525)

flap-structured DNA binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Agata Smogorzewska

5

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Stephen Elledge

6

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Ouathek Ouerfelli

object named as

Ouathek Ouerfelli

4

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author name string

Renjing Wang

1

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Nicole S Persky

2

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Barney Yoo

3

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Nikola P Pavletich

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair

7

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language of work or name

English

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publication date

28 November 2014

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published in

Science

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volume

346

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issue

6213

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page(s)

1127-30

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cites work

1 reference

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Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents

19 March 2017

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Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2

19 March 2017

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Human Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 Superfamily

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Advances in understanding the complex mechanisms of DNA interstrand cross-link repair

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Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair

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Generation, representation and flow of phase information in structure determination: recent developments in and around SHARP 2.0

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The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast

22 April 2017

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The differences between ICL repair during and outside of S phase

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FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair

27 September 2017

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KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents

27 September 2017

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FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair

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