Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics (Q24308344)

2

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Kevin B Jones

3

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Marina Pacheco

4

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Angela Goytain

5

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Shujun Lin

6

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Neal Poulin

7

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Lin Yi

8

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Fabio M Rossi

9

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Juergen Kast

10

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Mario R Capecchi

11

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T Michael Underhill

12

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Torsten O Nielsen

PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt

13

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language of work or name

English

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publication date

20 March 2012

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published in

Cancer Cell

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volume

21

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issue

3

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page(s)

333-47

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cites work

1 reference

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CIP2A inhibits PP2A in human malignancies

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The SYT-SSX fusion protein down-regulates the cell proliferation regulator COM1 in t(x;18) synovial sarcoma

19 March 2017

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CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation

19 March 2017

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Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization

19 March 2017

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Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis

19 March 2017

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ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation

19 March 2017

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Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus

19 March 2017

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Linking genome and proteome by mass spectrometry: large-scale identification of yeast proteins from two dimensional gels

19 March 2017

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Fusions of the SYT and SSX genes in synovial sarcoma

19 March 2017

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Role of histone H3 lysine 27 methylation in Polycomb-group silencing

19 March 2017

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A functional interaction between the histone deacetylase Rpd3 and the corepressor groucho in Drosophila development

19 March 2017

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Histone methyltransferase activity of a Drosophila Polycomb group repressor complex

19 March 2017

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Immunohistochemical staining for TLE1 distinguishes synovial sarcoma from histologic mimics

7 April 2017

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Small blue round cell tumor of the interosseous membrane bearing a t(2;22)(q34;q12)/EWS-CREB1 translocation: a case report

27 September 2017

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EGR1 reactivation by histone deacetylase inhibitors promotes synovial sarcoma cell death through the PTEN tumor suppressor

27 September 2017

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Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes

27 September 2017

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Emerging roles of ATF2 and the dynamic AP1 network in cancer

27 September 2017

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A carboxy-terminal affinity tag for the purification and mass spectrometric characterization of integral membrane proteins

27 September 2017

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Histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in clear cell sarcoma models

27 September 2017

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Synovial sarcoma: from genetics to genetic-based animal modeling

27 September 2017

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Histone deacetylase inhibitors reverse SS18-SSX-mediated polycomb silencing of the tumor suppressor early growth response 1 in synovial sarcoma

27 September 2017

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ATF-2 controls transcription of Maspin and GADD45 alpha genes independently from p53 to suppress mammary tumors

27 September 2017

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A conditional mouse model of synovial sarcoma: insights into a myogenic origin

27 September 2017

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Reduced levels of ATF-2 predispose mice to mammary tumors.

27 September 2017

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Gene expression profiling of human sarcomas: insights into sarcoma biology

27 September 2017

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Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress

27 September 2017

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Analysis of transforming activity of human synovial sarcoma-associated chimeric protein SYT-SSX1 bound to chromatin remodeling factor hBRM/hSNF2 alpha

27 September 2017

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The BTB/POZ domain of the Arabidopsis disease resistance protein NPR1 interacts with the repression domain of TGA2 to negate its function

27 September 2017

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Early growth response factor-1 mediates prostaglandin E2-dependent transcriptional suppression of cytokine-induced tumor necrosis factor-alpha gene expression in human macrophages and rheumatoid arthritis-affected synovial fibroblasts

30 May 2018

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Gene Expression Profiling of Synovial Sarcoma: Distinct Signature of Poorly Differentiated Type

30 May 2018

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Prospective evaluation of TLE1 as a diagnostic immunohistochemical marker in synovial sarcoma.

29 November 2018

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TLE1 expression is not specific for synovial sarcoma: a whole section study of 163 soft tissue and bone neoplasms.

29 November 2018

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TLE1 as a diagnostic immunohistochemical marker for synovial sarcoma emerging from gene expression profiling studies.

29 November 2018

1 reference

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Significant growth suppression of synovial sarcomas by the histone deacetylase inhibitor FK228 in vitro and in vivo

29 November 2018

1 reference

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Subcellular localization of activating transcription factor 2 in melanoma specimens predicts patient survival.

29 November 2018

1 reference

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Infrequent mutations of the activating transcription factor-2 gene in human lung cancer, neuroblastoma and breast cancer.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734954

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3734954

Molecular characterisation of soft tissue tumours: a gene expression study

29 November 2018

1 reference

12 December 2020

The synovial-sarcoma-associated SS18-SSX2 fusion protein induces epigenetic gene (de)regulation

1 reference

12 December 2020

TLE1 is a robust diagnostic biomarker for synovial sarcomas and correlates with t(X;18): analysis of 319 cases

1 reference

12 December 2020

SSX and the synovial-sarcoma-specific chimaeric protein SYT-SSX co-localize with the human Polycomb group complex

1 reference

12 December 2020

10.1016/J.CCR.2012.01.010

Identifiers

DOI

1 reference

1 reference

1 reference

PubMed publication ID

22439931

1 reference