PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt (Q24309413)

Pleckstrin homology like domain family A member 3

GOA release 2020-03-11

1 reference

phosphatidylinositol-3,5-bisphosphate binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

9

Hiroyuki Aburatani

Hiroyuki

Aburatani

1 reference

26 November 2023

3

Tatsuhiro Shibata

Tatsuhiro

Shibata

1 reference

26 November 2023

Tatsuya Kawase

1

Tatsuya

Kawase

1 reference

26 November 2023

Rieko Ohki

2

Rieko

Ohki

1 reference

26 November 2023

Shuichi Tsutsumi

4

Shuichi

Tsutsumi

1 reference

26 November 2023

Naoko Kamimura

5

Naoko

Kamimura

1 reference

26 November 2023

Johji Inazawa

6

Johji

Inazawa

1 reference

26 November 2023

Tsutomu Ohta

7

Tsutomu

Ohta

1 reference

26 November 2023

Hitoshi Ichikawa

8

Hitoshi

Ichikawa

1 reference

26 November 2023

Fumio Tashiro

10

Fumio

Tashiro

1 reference

26 November 2023

Yoichi Taya

11

Yoichi

Regulation of the p53 transcriptional activity.

Taya

1 reference

26 November 2023

language of work or name

English

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publication date

6 February 2009

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published in

Cell

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volume

136

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page(s)

535-50

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issue

3

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cites work

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p53 ubiquitination: Mdm2 and beyond

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Specificity in pleckstrin homology (PH) domain membrane targeting: a role for a phosphoinositide-protein co-operative mechanism.

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Targeting the PI3K-Akt pathway in human cancer: rationale and promise

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Surfing the p53 network

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Histone H3 lysine 4 methylation patterns in higher eukaryotic genes

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Post-translational modification of p53 in tumorigenesis

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Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis

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p53 target gene AEN is a nuclear exonuclease required for p53-dependent apoptosis

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Decision making by p53: life, death and cancer

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Modulation of cellular apoptotic potential: contributions to oncogenesis

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The p53 pathway: positive and negative feedback loops

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A p53-dominant transcriptional response to cisplatin in testicular germ cell tumor-derived human embryonal carcinoma.

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Signal-dependent membrane targeting by pleckstrin homology (PH) domains

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Placental overgrowth in mice lacking the imprinted gene Ipl

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Interleukin 3-dependent survival by the Akt protein kinase

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Reprimo, a new candidate mediator of the p53-mediated cell cycle arrest at the G2 phase

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Phosphoinositide binding by the pleckstrin homology domains of Ipl and Tih1

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Array-based comparative genomic hybridization analysis of high-grade neuroendocrine tumors of the lung.

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Dissecting functional roles of p53 N-terminal transactivation domains by microarray expression analysis

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

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Identification of novel p53 target genes in ionizing radiation response.

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Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells

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Selective cellular effects of overexpressed pleckstrin-homology domains that recognize PtdIns(3,4,5)P3 suggest their interaction with protein binding partners.

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