The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner (Q24308947)

positive regulation of apoptotic signaling pathway

GOA release 2020-03-11

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GOA release 2020-03-11

9

Maréne Landström

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author name string

Alessandro Sorrentino

1

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Noopur Thakur

2

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Susanne Grimsby

3

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Anders Marcusson

4

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Verena von Bulow

5

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Norbert Schuster

6

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Shouting Zhang

7

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Carl-Henrik Heldin

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

8

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language of work or name

English

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publication date

October 2008

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published in

Nature Cell Biology

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volume

10

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issue

10

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page(s)

1199-207

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cites work

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7 January 2021

Non-Smad TGF-beta signals

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7 January 2021

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

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7 January 2021

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

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7 January 2021

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

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7 January 2021

Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding

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7 January 2021

TAK1 participates in c-Jun N-terminal kinase signaling during Drosophila development

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7 January 2021

TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice.

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7 January 2021

Role of TAK1 and TAB1 in BMP signaling in early Xenopus development

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7 January 2021

Ubiquitin signalling in the NF-kappaB pathway

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7 January 2021

Regulating the regulators: control of protein ubiquitination and ubiquitin-like modifications by extracellular stimuli

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7 January 2021

TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology.

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7 January 2021

Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

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7 January 2021

Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

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7 January 2021

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

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7 January 2021

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

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7 January 2021

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

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7 January 2021

A direct interaction between TGFbeta activated kinase 1 and the TGFbeta type II receptor: implications for TGFbeta signalling and cardiac hypertrophy

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7 January 2021

Switching signals on or off by receptor dimerization

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7 January 2021

Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif

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7 January 2021

CD40 signaling through tumor necrosis factor receptor-associated factors (TRAFs). Binding site specificity and activation of downstream pathways by distinct TRAFs

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7 January 2021

Structural basis for the interaction of TAK1 kinase with its activating protein TAB1.

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7 January 2021

Preferred in vivo ubiquitination sites.

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7 January 2021

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

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7 January 2021

Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3

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7 January 2021

TGFbeta1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner.

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7 January 2021

Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor

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7 January 2021

Identifiers

DOI

10.1038/NCB1780

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1083516

1023242636

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1083516

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference