Nucleophosmin interacts with and inhibits the catalytic function of eukaryotic initiation factor 2 kinase PKR (Q24311493)

Nucleophosmin 1

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negative regulation of translation

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Eukaryotic translation initiation factor 2-alpha kinase 2

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Nucleophosmin 1

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author name string

Qishen Pang

1

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Tracy A Christianson

2

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Tara Koretsky

3

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Hanqian Carlson

4

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Larry David

5

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Winifred Keeble

6

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Gregory R Faulkner

7

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Ashley Speckhart

8

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Grover C Bagby

Journal of Biological Chemistry

9

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language of work or name

English

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publication date

24 October 2003

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published in

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volume

278

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issue

43

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page(s)

41709-17

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cites work

Translational control: the cancer connection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

PKR, apoptosis and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Impact of virus infection on host cell protein synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Antiviral actions of interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Phosphorylation of eukaryotic translation initiation factor 2 mediates apoptosis in response to activation of the double-stranded RNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Binding of double-stranded RNA to protein kinase PKR is required for dimerization and promotes critical autophosphorylation events in the activation loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Host defense, viruses and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Dominant negative function by an alternatively spliced form of the interferon-inducible protein kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Double-stranded RNA-dependent protein kinase mediates c-Myc suppression induced by type I interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

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21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Endoplasmic reticulum stress-induced cysteine protease activation in cortical neurons: effect of an Alzheimer's disease-linked presenilin-1 knock-in mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Involvement of double-stranded RNA-dependent protein kinase and phosphorylation of eukaryotic initiation factor-2alpha in neuronal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Selective pressure as an essential force in molecular evolution of myeloid leukemic clones: a view from the window of Fanconi anemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Characterization of the cDNA encoding human nucleophosmin and studies of its role in normal and abnormal growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Decrease in nucleophosmin/B23 mRNA and telomerase activity during indomethacin-induced apoptosis of gastric KATO-III cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

The Fanconi anemia protein FANCC binds to and facilitates the activation of STAT1 by gamma interferon and hematopoietic growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Expression of unphosphorylated form of human double-stranded RNA-activated protein kinase in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

DNA cloning and amino acid sequence determination of a major constituent protein of mammalian nucleoli. Correspondence of the nucleoplasmin-related protein NO38 to mammalian protein B23.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Identification of double-stranded RNA-binding domains in the interferon-induced double-stranded RNA-activated p68 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

PKR; a sentinel kinase for cellular stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

FANCC interacts with Hsp70 to protect hematopoietic cells from IFN-gamma/TNF-alpha-mediated cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

An essential role for the interferon-inducible, double-stranded RNA-activated protein kinase PKR in the tumor necrosis factor-induced apoptosis in U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Identification of mRNAs that show modulated expression during colon carcinoma cell differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

The anti-apoptotic function of Hsp70 in the interferon-inducible double-stranded RNA-dependent protein kinase-mediated death signaling pathway requires the Fanconi anemia protein, FANCC

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

The Fanconi anemia group C gene product: signaling functions in hematopoietic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Bone marrow failure syndromes in children

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Congenital bone marrow failure syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

The human ribosomal protein L6 gene in a critical region for Noonan syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Increased expression of Hsp40 chaperones, transcriptional factors, and ribosomal protein Rpp0 can cure yeast prions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Involvement of ribosomal proteins in regulating cell growth and apoptosis: translational modulation or recruitment for extraribosomal activity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

The nuclear lamina and inherited disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

Abrogation of translation initiation factor eIF-2 phosphorylation causes malignant transformation of NIH 3T3 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

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Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

7 January 2021

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

7 January 2021

Nucleophosmin/B23 regulates the susceptibility of human leukemia HL-60 cells to sodium butyrate-induced apoptosis and inhibition of telomerase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

7 January 2021

Interaction of nucleolar phosphoprotein B23 with nucleic acids

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

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Mortalization of human promyelocytic leukemia HL-60 cells to be more susceptible to sodium butyrate-induced apoptosis and inhibition of telomerase activity by down-regulation of nucleophosmin/B23

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

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Reduced numatrin/B23/nucleophosmin labeling in apoptotic Jurkat T-lymphoblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

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Mapping the functional domains of nucleolar protein B23

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

7 January 2021

Role of double-stranded RNA-dependent protein kinase in mediating hypersensitivity of Fanconi anemia complementation group C cells to interferon gamma, tumor necrosis factor-alpha, and double-stranded RNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

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Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301392200

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