Dominant negative function by an alternatively spliced form of the interferon-inducible protein kinase PKR. (Q43559384)

24 November 2017

Dominant negative function by an alternatively spliced form of the interferon-inducible protein kinase PKR. (English)

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24 November 2017

Li S

1

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24 November 2017

Koromilas AE

series ordinal

2

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24 November 2017

language of work or name

English

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publication date

5 February 2001

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Journal of Biological Chemistry

24 November 2017

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24 November 2017

276

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24 November 2017

17

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24 November 2017

13881-13890

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Translational control: the cancer connection

24 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

The double-stranded RNA-dependent protein kinase PKR: structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Translational control in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

The emerging role of the interferon-induced PKR protein kinase as an apoptotic effector: a new face of death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Mutants of the RNA-dependent protein kinase (PKR) lacking double-stranded RNA binding domain I can act as transdominant inhibitors and induce malignant transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Essential role for the dsRNA-dependent protein kinase PKR in innate immunity to viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

The murine double-stranded RNA-dependent protein kinase PKR is required for resistance to vesicular stomatitis virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Proteins binding to duplexed RNA: one motif, multiple functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Structural organization of the human gene (PKR) encoding an interferon-inducible RNA-dependent protein kinase (PKR) and differences from its mouse homolog

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Mechanism of interferon action: structure of the mouse PKR gene encoding the interferon-inducible RNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

The murine PKR tumor suppressor gene is rearranged in a lymphocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

A diminished activation capacity of the interferon-inducible protein kinase PKR in human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Structural features of adenovirus 2 virus-associated RNA required for binding to the protein kinase DAI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Double-stranded-RNA-dependent protein kinase and TAR RNA-binding protein form homo- and heterodimers in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Functional characterization of the RNA-binding domain and motif of the double-stranded RNA-dependent protein kinase DAI (PKR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Mammalian eukaryotic initiation factor 2 alpha kinases functionally substitute for GCN2 protein kinase in the GCN4 translational control mechanism of yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Structural requirements for double-stranded RNA binding, dimerization, and activation of the human eIF-2 alpha kinase DAI in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Regulation of the protein kinase PKR by the vaccinia virus pseudosubstrate inhibitor K3L is dependent on residues conserved between the K3L protein and the PKR substrate eIF2alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

The interferon-inducible protein kinase PKR modulates the transcriptional activation of immunoglobulin kappa gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Functional characterization of and cooperation between the double-stranded RNA-binding motifs of the protein kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Genomic features of human PKR: alternative splicing and a polymorphic CGG repeat in the 5'-untranslated region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Double-stranded (ds) RNA binding and not dimerization correlates with the activation of the dsRNA-dependent protein kinase (PKR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Nuclear localization of the interferon-inducible protein kinase PKR in human cells and transfected mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Ultrastructural localization of interferon-inducible double-stranded RNA-activated enzymes in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Nuclear factor-90 of activated T-cells: A double-stranded RNA-binding protein and substrate for the double-stranded RNA-dependent protein kinase, PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

The double-stranded RNA-binding protein X1rbpa promotes RNA strand annealing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

A cis-acting element in the 3'-untranslated region of human TNF-alpha mRNA renders splicing dependent on the activation of protein kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M008140200

21 January 2018

Identifiers

DOI

10.1074/JBC.M008140200

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