Regulated association of protein kinase B/Akt with breast tumor kinase (Q24314300)

negative regulation of protein tyrosine kinase activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

6

Carol A Lange

Carol A

Lange

1 reference

20 April 2024

Ping Zhang

1

Ping

Zhang

1 reference

20 April 2024

Julie Hanson Ostrander

2

Julie Hanson

Ostrander

1 reference

20 April 2024

Emily J Faivre

3

Emily J

Faivre

1 reference

20 April 2024

Abby Olsen

4

Abby

Olsen

1 reference

20 April 2024

Daniel Fitzsimmons

5

Daniel

Journal of Biological Chemistry

Fitzsimmons

1 reference

20 April 2024

language of work or name

English

0 references

publication date

21 January 2005

0 references

published in

0 references

volume

280

0 references

page(s)

1982-91

0 references

issue

3

0 references

cites work

Brk, a breast tumor-derived non-receptor protein-tyrosine kinase, sensitizes mammary epithelial cells to epidermal growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Use of RNA interference to validate Brk as a novel therapeutic target in breast cancer: Brk promotes breast carcinoma cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Brk, Srm, Frk, and Src42A Form a Distinct Family of Intracellular Src-Like Tyrosine Kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

A role for the epithelial-cell-specific tyrosine kinase Sik during keratinocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

General effect of Sam68 on Rev/Rex regulated expression of complex retroviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Sam68 enhances the cytoplasmic utilization of intron-containing RNA and is functionally regulated by the nuclear kinase Sik/BRK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

A novel adaptor-like protein which is a substrate for the non-receptor tyrosine kinase, BRK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Akt activation by growth factors is a multiple-step process: the role of the PH domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Interaction between Src and a C-terminal proline-rich motif of Akt is required for Akt activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Solution structure and backbone dynamics of the non-receptor protein-tyrosine kinase-6 Src homology 2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Convergence of progesterone and epidermal growth factor signaling in breast cancer. Potentiation of mitogen-activated protein kinase pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Activation of human pp60c-src

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Role of the Brk SH3 domain in substrate recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Unravelling the activation mechanisms of protein kinase B/Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

The Brk protein tyrosine kinase as a therapeutic target in cancer: opportunities and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

p19ARF directly and differentially controls the functions of c-Myc independently of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

Identification of tyrosine kinases overexpressed in head and neck cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

BRK tyrosine kinase expression in a high proportion of human breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

7 January 2021

Convergence of progesterone with growth factor and cytokine signaling in breast cancer. Progesterone receptors regulate signal transducers and activators of transcription expression and activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

7 January 2021

A matter of life and cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

7 January 2021

The many forks in FOXO's road

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412038200

7 January 2021