RIG-I/MDA5/MAVS are required to signal a protective IFN response in rotavirus-infected intestinal epithelium (Q24321688)

Gene Ontology release 2020-05-02

1 reference

GOA release 2020-03-11

negative regulation of RIG-I signaling pathway

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GOA release 2020-03-11

author name string

Alexis H Broquet

1

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Yoshihiro Hirata

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Christopher S McAllister

3

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Martin F Kagnoff

Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

4

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language of work or name

English

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publication date

1 February 2011

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published in

Journal of Immunology

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volume

186

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page(s)

1618-26

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issue

3

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cites work

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PACT, a double-stranded RNA binding protein acts as a positive regulator for type I interferon gene induced by Newcastle disease virus.

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Rotavirus proteins: structure and assembly

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Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

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Pathogen recognition and innate immunity

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Recognition of viruses by cytoplasmic sensors

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Transcriptional signaling by double-stranded RNA: role of TLR3.

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Cell type-specific involvement of RIG-I in antiviral response

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The specific and essential role of MAVS in antiviral innate immune responses

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Commensal gut bacteria: mechanisms of immune modulation

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CARD games between virus and host get a new player

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VISA is an adapter protein required for virus-triggered IFN-beta signaling

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Toll-like receptors and RNA helicases: two parallel ways to trigger antiviral responses

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The interferon response circuit: induction and suppression by pathogenic viruses

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Interferon gamma and interleukin 1, but not interferon alfa, inhibit rotavirus entry into human intestinal cell lines

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Coupling of rotavirus genome replication and capsid assembly.

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The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors

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Interactions between rotavirus and gastrointestinal cells

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Man the barrier! Strategic defences in the intestinal mucosa

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The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.

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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

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Innate immune recognition of viral infection

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The double-stranded-RNA-binding motif: interference and much more

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Viruses causing gastroenteritis

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Rotavirus nonstructural protein 1 subverts innate immune response by inducing degradation of IFN regulatory factor 3

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Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2

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LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

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Mechanism of intraparticle synthesis of the rotavirus double-stranded RNA genome.

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Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

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The role of interferons in rotavirus infections and protection.

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Lack of a Role for Type I and Type II Interferons in the Resolution of Rotavirus-Induced Diarrhea and Infection in Mice

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7 January 2021

Rotavirus and reovirus modulation of the interferon response

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7 January 2021

Viral sensors: diversity in pathogen recognition

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7 January 2021

5'-Triphosphate RNA is the ligand for RIG-I

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7 January 2021

RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

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Signal integration via PKR.

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Sensing of viral infection and activation of innate immunity by toll-like receptor 3

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Antiviral actions of interferons

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Clearance of Citrobacter rodentium requires B cells but not secretory immunoglobulin A (IgA) or IgM antibodies.

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7 January 2021

Rotavirus infection is not associated with small intestinal fluid secretion in the adult mouse.

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7 January 2021

Role of interferon in homologous and heterologous rotavirus infection in the intestines and extraintestinal organs of suckling mice

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7 January 2021

Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

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Rotavirus infection enhances lipopolysaccharide-induced intussusception in a mouse model

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Establishment and Maintenance of the Innate Antiviral Response to West Nile Virus Involves both RIG-I and MDA5 Signaling through IPS-1

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7 January 2021

RNA- and virus-independent inhibition of antiviral signaling by RNA helicase LGP2

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7 January 2021

Hsp70 negatively controls rotavirus protein bioavailability in caco-2 cells infected by the rotavirus RF strain

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Role of interferon regulatory factor 3 in type I interferon responses in rotavirus-infected dendritic cells and fibroblasts

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Impaired antiviral response and alpha/beta interferon induction in mice lacking beta interferon.

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Pathogenesis of intestinal and systemic rotavirus infection

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Characterization of homologous and heterologous rotavirus-specific T-cell responses in infant and adult mice.

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Cytopathogenesis and inhibition of host gene expression by RNA viruses

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Production of MDC/CCL22 by human intestinal epithelial cells

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Microbial-epithelial cell crosstalk during inflammation: the host response

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Replication and Transcription of the Rotavirus Genome

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Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

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Subcellular localization of Toll-like receptor 3 in human dendritic cells

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Protein kinase R mediates intestinal epithelial gene remodeling in response to double-stranded RNA and live rotavirus

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.1002862

7 January 2021

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

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The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

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Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses

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Recognition of double-stranded RNA by TLR3 induces severe small intestinal injury in mice

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Activation of innate immune defense mechanisms by signaling through RIG-I/IPS-1 in intestinal epithelial cells

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https://api.crossref.org/works/10.4049%2FJIMMUNOL.1002862

7 January 2021